Activation of the human beta-globin promoter in K562 cells by DNA sequences 5' to the fetal gamma- or embryonic zeta-globin genes.

Activation of the human beta-globin promoter in K562 cells by DNA sequences 5' to the fetal gamma- or embryonic zeta-globin genes.

Item
http://www.wikidata.org/entity/Q35576874
Identification of a stage selector element in the human gamma-globin gene promoter that fosters preferential interaction with the 5' HS2 enhancer when in competition with the beta-promoter.Sequences downstream of the erythroid promoter are required for high level expression of the human alpha-spectrin gene.Enhancers increase the probability but not the level of gene expression.Functional profile of the human fetal gamma-globin gene upstream promoter region.Nuclear protein factors and erythroid transcription of the human A gamma-globin geneA 46 base pair enhancer sequence within the locus activating region is required for induced expression of the gamma-globin gene during erythroid differentiation.The human beta-globin gene contains multiple regulatory regions: identification of one promoter and two downstream enhancers.Roles of fetal G gamma-globin promoter elements and the adult beta-globin 3' enhancer in the stage-specific expression of globin genes.Functional erythroid promoters created by interaction of the transcription factor GATA-1 with CACCC and AP-1/NFE-2 elements.Inducibility of the HS II enhancer depends on binding of an erythroid specific nuclear protein.A naturally occurring gamma globin gene mutation enhances SP1 binding activity.Mutations in two regions upstream of the A gamma globin gene canonical promoter affect gene expression.Efficient integration of short interspersed element-flanked foreign DNA via homologous recombination.
P2860

Activation of the human beta-globin promoter in K562 cells by DNA sequences 5' to the fetal gamma- or embryonic zeta-globin genes.

Item
http://www.wikidata.org/entity/Q35576874
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
Activation of the human beta-g ...... r embryonic zeta-globin genes.
@ast
Activation of the human beta-g ...... r embryonic zeta-globin genes.
@en
type
label
Activation of the human beta-g ...... r embryonic zeta-globin genes.
@ast
Activation of the human beta-g ...... r embryonic zeta-globin genes.
@en
prefLabel
Activation of the human beta-g ...... r embryonic zeta-globin genes.
@ast
Activation of the human beta-g ...... r embryonic zeta-globin genes.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Activation of the human beta-g ...... r embryonic zeta-globin genes.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932