TREM2 is associated with increased risk for Alzheimer's disease in African Americans.
about
TREM2 in CNS homeostasis and neurodegenerative diseasemicroRNA-Based Biomarkers and the Diagnosis of Alzheimer's DiseaseAfrican American exome sequencing identifies potential risk variants at Alzheimer disease lociExpression and processing analyses of wild type and p.R47H TREM2 variant in Alzheimer's disease brains.Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2).Resequencing analysis of five Mendelian genes and the top genes from genome-wide association studies in Parkinson's Disease.Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status.Neuropathologic differences by race from the National Alzheimer's Coordinating CenterLRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways.Soluble TREM2 induces inflammatory responses and enhances microglial survival.TREM2 in Neurodegenerative Diseases.TREM2-Ligand Interactions in Health and Disease.Novel susceptibility loci for Alzheimer's disease.Proteomics as an innovative tool to investigate frontotemporal disorders.Identification of a rare coding variant in TREM2 in a Chinese individual with Alzheimer's diseaseFrom Common to Rare Variants: The Genetic Component of Alzheimer Disease.Neuroinflammation in Neurodegenerative Disorders-a Review.Functional Roles of the Interaction of APP and Lipoprotein Receptors.Alzheimer's Disease: Biomarkers in the Genome, Blood, and Cerebrospinal Fluid.Microglia-Mediated Neuroprotection, TREM2, and Alzheimer's Disease: Evidence From Optical Imaging.Race modifies the relationship between cognition and Alzheimer's disease cerebrospinal fluid biomarkers.Intracellular trafficking of TREM2 is regulated by presenilin 1.The role of astrocytes in amyloid production and Alzheimer's disease.Assessment of the Genetic Architecture of Alzheimer's Disease Risk in Rate of Memory Decline.Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation.Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2).Pleiotropic Effects of Variants in Dementia Genes in Parkinson Disease.TREM2 regulates innate immunity in Alzheimer's disease.High-affinity interactions and signal transduction between Aβ oligomers and TREM2Inflammation as a central mechanism in Alzheimer's disease
P2860
Q26785919-83B6903F-6DC8-44B0-8AF5-747EBD472526Q26798619-1132F4D4-7081-4C71-AAED-F54A51FE556BQ33608441-616159CF-DCC0-4362-90BB-2CF020EE503FQ36204253-553ABC4D-C9AF-4645-802A-98382AD2E2E0Q36283527-85806775-78C2-4B59-94D7-594CD377B39BQ36815405-7892D51B-2374-48F7-A6AB-DF1D51737877Q36901561-85F116CC-CBBB-4F94-A209-EBA3A9C9A6F5Q36995445-B3DA9EA5-59A5-4CC9-96F3-C817E8E18EA8Q37487912-1BC00504-44BA-426C-8A6A-2A9743BA1703Q38402630-EE6ADDAE-40F1-4166-860C-1E7D5F0B1D09Q38646212-8837C401-5083-4D8D-A01E-D07A2800F1BAQ38692159-5357A82D-5961-407A-8ADB-7D0B2A37C566Q38801607-1BFC824B-6F8B-490E-8EE0-52859B1E641DQ38802995-EDD13414-0967-4C9D-BB5B-7943BF349947Q38855278-FE47E17F-266D-40A7-A8C3-96A3386C2614Q39047085-E1F7FB9C-7686-4020-9316-DF32D7DB8E3DQ39173756-EF9D98CB-982F-4935-9AB3-6E75B02C8A68Q39180867-669232F2-DB38-4CFB-A84C-7F2DFE71BD0CQ39217840-64CF1C5A-68AA-4A50-B566-2C6E564A2A90Q46598391-0AA912A4-AEE0-4B69-8C06-A32B50495EDDQ46805247-B0A6C88D-1491-4F54-A983-3B4B27D335D3Q47151761-B23DC99B-A43B-48B5-A323-15207132127AQ47296419-86FEDDB8-78E8-4638-9500-AE3E2BE0C1CBQ50534616-E9BC699C-7D62-4166-88FF-AE6D16C79019Q51573853-9E4CDF00-98BF-4515-876B-EE1E5ED55A66Q51758945-93B73F97-D5B4-4788-92F8-8C4396760034Q53397478-3AC03DC5-C5FB-4911-8D53-1E64CE597463Q55158988-9FBB84F6-92A5-45F3-9031-6558EF6D46C8Q57809898-792AE9A1-D843-4C91-83E2-B1031989794AQ58555818-4E6813FA-A9E0-41CF-B051-29CA2F88169E
P2860
TREM2 is associated with increased risk for Alzheimer's disease in African Americans.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
TREM2 is associated with increased risk for Alzheimer's disease in African Americans.
@ast
TREM2 is associated with increased risk for Alzheimer's disease in African Americans.
@en
type
label
TREM2 is associated with increased risk for Alzheimer's disease in African Americans.
@ast
TREM2 is associated with increased risk for Alzheimer's disease in African Americans.
@en
prefLabel
TREM2 is associated with increased risk for Alzheimer's disease in African Americans.
@ast
TREM2 is associated with increased risk for Alzheimer's disease in African Americans.
@en
P2093
P2860
P50
P1476
TREM2 is associated with increased risk for Alzheimer's disease in African Americans.
@en
P2093
Allan I Levey
Carlos Cruchaga
David Carrell
Dwani Patel
Hugh Hendrie
James J Lah
Jill Murrell
Michaela Kachadoorian
Minerva M Carrasquillo
Neill R Graff-Radford
P2860
P2888
P356
10.1186/S13024-015-0016-9
P407
P50
P577
2015-04-10T00:00:00Z
P5875
P6179
1049435583