Thrombin induces endothelial cell growth via both a proteolytic and a non-proteolytic pathway.
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Thrombin stimulates fibroblast procollagen production via proteolytic activation of protease-activated receptor 1Secretion without GolgiOvarian cancer, the coagulation pathway, and inflammationFrom principle to practice: bridging the gap in patient profilingActivation of pro-(matrix metalloproteinase-2) (pro-MMP-2) by thrombin is membrane-type-MMP-dependent in human umbilical vein endothelial cells and generates a distinct 63 kDa active speciesProtease-activated receptor-4: a novel mechanism of inflammatory pain modulationExogenous thrombin delivery promotes collateral capillary arterialization and tissue reperfusion in the murine spinotrapezius muscle ischemia model.Vascular protease receptors: integrating haemostasis and endothelial cell functions.PAR1-dependent COX-2/PGE2 production contributes to cell proliferation via EP2 receptors in primary human cardiomyocytesThe hemostatic system and angiogenesis in malignancy.Protease-activated receptor (PAR)-independent growth and pro-inflammatory actions of thrombin on human cultured airway smooth muscle.Drotrecogin alfa (activated): a novel therapeutic strategy for severe sepsis.Novel cross-talk between three cardiovascular regulators: thrombin cleavage fragment of Jagged1 induces fibroblast growth factor 1 expression and releaseCancer and Thrombosis: The Platelet Perspective.Pathologies at the nexus of blood coagulation and inflammation: thrombin in hemostasis, cancer, and beyondEpistatic effects of multiple receptor genes on pathophysiology of asthma - its limits and potential for clinical application.Protease-activated receptor 4: a critical participator in inflammatory response.Intimal hyperplasia following vascular injury is not inhibited by an antisense thrombin receptor oligodeoxynucleotide.Effector protease receptor 1 mediates the mitogenic activity of factor Xa for vascular smooth muscle cells in vitro and in vivo.Thrombin and TNF-alpha/IL-1beta synergistically induce fibroblast-mediated collagen gel degradation.PAR1-dependent and independent increases in COX-2 and PGE2 in human colonic myofibroblasts stimulated by thrombin.Cultured rat glomerular epithelial cells show gene expression and production of transforming growth factor-beta: expression is enhanced by thrombin.Galpha12 stimulates c-Jun NH2-terminal kinase through the small G proteins Ras and Rac.Pro- and anti-inflammatory actions of thrombin: a distinct role for proteinase-activated receptor-1 (PAR1).Thrombin has a bimodal effect on glioma cell growth.Synergistic actions of a thrombin-derived synthetic peptide and a thrombin receptor-activating peptide in stimulating fibroblast mitogenesis.Protease-activated receptors as therapeutic targets in visceral pain.Thrombin cleaves the high molecular weight forms of basic fibroblast growth factor (FGF-2): a novel mechanism for the control of FGF-2 and thrombin activity.Proteinase-activated receptor-1 agonists attenuate nociception in response to noxious stimuli.Shear stress-induced release of basic fibroblast growth factor from endothelial cells is mediated by matrix interaction via integrin alpha(v)beta3.Thrombin induces angiogenesis and vascular endothelial growth factor expression in human endothelial cells: possible relevance to HIF-1alpha.The non-proteolytically active thrombin peptide TP508 stimulates angiogenic sprouting.
P2860
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P2860
Thrombin induces endothelial cell growth via both a proteolytic and a non-proteolytic pathway.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Thrombin induces endothelial c ...... and a non-proteolytic pathway.
@en
Thrombin induces endothelial c ...... and a non-proteolytic pathway.
@nl
type
label
Thrombin induces endothelial c ...... and a non-proteolytic pathway.
@en
Thrombin induces endothelial c ...... and a non-proteolytic pathway.
@nl
prefLabel
Thrombin induces endothelial c ...... and a non-proteolytic pathway.
@en
Thrombin induces endothelial c ...... and a non-proteolytic pathway.
@nl
P2093
P2860
P356
P1433
P1476
Thrombin induces endothelial c ...... and a non-proteolytic pathway.
@en
P2093
P2860
P304
P356
10.1042/BJ3030227
P407
P478
303 ( Pt 1)
P577
1994-10-01T00:00:00Z