Primary structure of the gene encoding the bifunctional dihydrofolate reductase-thymidylate synthase of Leishmania major.
about
Antifolate drug selection results in duplication and rearrangement of chromosome 7 in Plasmodium chabaudiBacteriophage T4 genetic homologies with bacteria and eucaryotesEvolution of nuclear ribosomal RNAs in kinetoplastid protozoa: perspectives on the age and origins of parasitismAutoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthaseProbing the structure of Leishmania major DHFR TS and structure based virtual screening of peptide library for the identification of anti-leishmanial leads.Isolation of genes mediating resistance to inhibitors of nucleoside and ergosterol metabolism in Leishmania by overexpression/selection.Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 geneAmino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum.Molecular cloning and characterization of the immunologically protective surface glycoprotein GP46/M-2 of Leishmania amazonensis.Isolation and expression of the Pneumocystis carinii thymidylate synthase geneIsolation and expression of the Pneumocystis carinii dihydrofolate reductase gene.Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene.The roles of pteridine reductase 1 and dihydrofolate reductase-thymidylate synthase in pteridine metabolism in the protozoan parasite Leishmania major.Cloning and characterization of the thymidylate synthase gene from Lactococcus lactis subsp. lactis.Leishmania is not prone to develop resistance to tamoxifen.Nuclease mapping and DNA sequence analysis of transcripts from the dihydrofolate reductase-thymidylate synthase (R) region of Leishmania major.PTR1: a reductase mediating salvage of oxidized pteridines and methotrexate resistance in the protozoan parasite Leishmania major.Genetic dissection of pyrimidine biosynthesis and salvage in Leishmania donovani.The biology of Pneumocystis carinii.Sequence and S1 nuclease mapping of the 5' region of the dihydrofolate reductase-thymidylate synthase gene of Leishmania major.Cloning and characterization of a photolyase gene from the cyanobacterium Anacystis nidulans.Increased expression of LD1 genes transcribed by RNA polymerase I in Leishmania donovani as a result of duplication into the rRNA gene locus.Stable transfection of the human parasite Leishmania major delineates a 30-kilobase region sufficient for extrachromosomal replication and expressionTranscriptional mapping of the amplified region encoding the dihydrofolate reductase-thymidylate synthase of Leishmania major reveals a high density of transcripts, including overlapping and antisense RNAs.Amplified DNAs in laboratory stocks of Leishmania tarentolae: extrachromosomal circles structurally and functionally similar to the inverted-H-region amplification of methotrexate-resistant Leishmania major.Structure and expression of a tandem gene pair in Leishmania donovani that encodes a protein structurally homologous to eucaryotic cation-transporting ATPases.Essential protein-protein interactions between Plasmodium falciparum thymidylate synthase and dihydrofolate reductase domains.Folate metabolic pathways in LeishmaniaFrom crystal to compound: structure-based antimalarial drug discovery.Novel biochemical pathways in parasitic protozoa.Biomedical science and the third world. Under the volcano. Recent studies on thymidylate synthase.Selection against the dihydrofolate reductase-thymidylate synthase (DHFR-TS) locus as a probe of genetic alterations in Leishmania major.Sequence and analysis of chromosome I of the amitochondriate intracellular parasite Encephalitozoon cuniculi (Microspora)Sequence of the dihydrofolate reductase-thymidylate synthase (DHFR-TS) gene of Leishmania amazonensis.Characterization of the 'unusual' mobility of large circular DNAs in pulsed field-gradient electrophoresis.Molecular cloning and expression of adenosine kinase from Leishmania donovani: identification of unconventional P-loop motifAmplification of a new region of DNA in an unselected laboratory stock of L. tarentolae: the T region.Shotgun cloning and characterization of the thymidylate synthase-encoding gene from Mycobacterium bovis BCG.Characterization of quinonoid-dihydropteridine reductase (QDPR) from the lower eukaryote Leishmania major.The extremely halophilic archaeon Haloferax volcanii has two very different dihydrofolate reductases.
P2860
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P2860
Primary structure of the gene encoding the bifunctional dihydrofolate reductase-thymidylate synthase of Leishmania major.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Primary structure of the gene ...... synthase of Leishmania major.
@ast
Primary structure of the gene ...... synthase of Leishmania major.
@en
type
label
Primary structure of the gene ...... synthase of Leishmania major.
@ast
Primary structure of the gene ...... synthase of Leishmania major.
@en
prefLabel
Primary structure of the gene ...... synthase of Leishmania major.
@ast
Primary structure of the gene ...... synthase of Leishmania major.
@en
P2093
P2860
P356
P1476
Primary structure of the gene ...... synthase of Leishmania major.
@en
P2093
J S Cordingley
S M Beverley
T E Ellenberger
P2860
P304
P356
10.1073/PNAS.83.8.2584
P407
P577
1986-04-01T00:00:00Z