Induction of drug metabolism: the role of nuclear receptors.
about
The evolution of drug-activated nuclear receptors: one ancestral gene diverged into two xenosensor genes in mammalsTandem machine learning for the identification of genes regulated by transcription factors.BIPAD: a web server for modeling bipartite sequence elements.Possible drug-drug interaction in dogs and cats resulted from alteration in drug metabolism: A mini reviewPolyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related DiseasesRole of pregnane X receptor in chemotherapeutic treatmentModulation of xenobiotic receptors by steroidsPhenobarbital induces alterations in the proteome of hepatocytes and mesenchymal cells of rat liversStructural and Functional Analysis of the Human Nuclear Xenobiotic Receptor PXR in Complex with RXRαAccess Path to the Ligand Binding Pocket May Play a Role in Xenobiotics Selection by AhRThe Alterations in the Expression and Function of P-Glycoprotein in Vitamin A-Deficient Rats as well as the Effect of Drug Disposition in VivoCytosolic sulfotransferase 1A3 is induced by dopamine and protects neuronal cells from dopamine toxicity: role of D1 receptor-N-methyl-D-aspartate receptor couplingActive nuclear receptors exhibit highly correlated AF-2 domain motionsPharmacogenomic and clinical data link non-pharmacokinetic metabolic dysregulation to drug side effect pathogenesisCytochrome P450 CYP2 genes in the common cormorant: Evolutionary relationships with 130 diapsid CYP2 clan sequences and chemical effects on their expressionSexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR).The transcriptional regulation of the human CYP2C genesEffects of hepatic drug-metabolizing enzyme induction on clinical pathology parameters in animals and man.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Identification and developmental expression of the full complement of Cytochrome P450 genes in ZebrafishRetinoid X receptor-alpha-dependent transactivation by a naturally occurring structural variant of human constitutive androstane receptor (NR1I3).Development of a common carp (Cyprinus carpio) pregnane X receptor (cPXR) transactivation reporter assay and its activation by azole fungicides and pharmaceutical chemicals.Pregnane X receptor suppresses proliferation and tumourigenicity of colon cancer cells.Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolism, Intermediary Metabolism, and Cell Proliferation.Caenorhabditis elegans metabolic gene regulatory networks govern the cellular economy.Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.Pregnane X receptor and constitutive androstane receptor at the crossroads of drug metabolism and energy metabolism.Cytochrome P450 and xenobiotic receptor humanized mice.Cytochrome P450 regulation: the interplay between its heme and apoprotein moieties in synthesis, assembly, repair, and disposal.Sucralose, a synthetic organochlorine sweetener: overview of biological issuesXenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.Dose separation does not overcome the pharmacokinetic interaction between fosamprenavir and lopinavir/ritonavirIdentification of pregnane X receptor ligands using time-resolved fluorescence resonance energy transfer and quantitative high-throughput screening.Identification of gene co-expression clusters in liver tissues from multiple porcine populations with high and low backfat androstenone phenotype.SOX11 identified by target gene evaluation of miRNAs differentially expressed in focal and non-focal brain tissue of therapy-resistant epilepsy patientsPrediction of gestational age-dependent induction of in vivo hepatic CYP3A activity based on HepaRG cells and human hepatocytes.In the regulation of cytochrome P450 genes, phenobarbital targets LKB1 for necessary activation of AMP-activated protein kinaseStress- (and diet-) related regulation of hepatic nuclear receptors and its relevance for ABC-transporter functions.Xenobiotic- and vitamin D-responsive induction of the steroid/bile acid-sulfotransferase Sult2A1 in young and old mice: the role of a gene enhancer in the liver chromatin.Pharmacogenetics - five decades of therapeutic lessons from genetic diversity.
P2860
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P2860
Induction of drug metabolism: the role of nuclear receptors.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Induction of drug metabolism: the role of nuclear receptors.
@ast
Induction of drug metabolism: the role of nuclear receptors.
@en
type
label
Induction of drug metabolism: the role of nuclear receptors.
@ast
Induction of drug metabolism: the role of nuclear receptors.
@en
prefLabel
Induction of drug metabolism: the role of nuclear receptors.
@ast
Induction of drug metabolism: the role of nuclear receptors.
@en
P356
P1476
Induction of drug metabolism: the role of nuclear receptors
@en
P2093
Urs A Meyer
P304
P356
10.1124/PR.55.4.2
P577
2003-12-01T00:00:00Z