Transforming gene from human stomach cancers and a noncancerous portion of stomach mucosa
about
Genomic sequence of hst, a transforming gene encoding a protein homologous to fibroblast growth factors and the int-2-encoded proteinMolecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion propertyIdentification of the CAB2/hCOS16 gene required for the repair of DNA double-strand breaks on a core amplified region of the 17q12 locus in breast and gastric cancersInhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3BFibroblast growth factor receptor-4 shows novel features in genomic structure, ligand binding and signal transductioncDNA sequence of human transforming gene hst and identification of the coding sequence required for transforming activityMxi1 mutations in human neurofibrosarcomasK-sam, an amplified gene in stomach cancer, is a member of the heparin-binding growth factor receptor genesExtending the family table: Insights from beyond vertebrates into the regulation of embryonic development by FGFsLoss of heterozygosity on chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung.Establishment of a highly sensitive and specific exon-trapping systemAdenovirus-mediated transfer of HST-1/FGF-4 gene protects mice from lethal irradiation.Effective prevention of thrombocytopenia in mice using adenovirus-mediated transfer of HST-1 (FGF-4) geneAdenovirus-mediated transfer of the HST-1 (FGF4) gene induces increased levels of platelet count in vivo.Human HST1 (HSTF1) gene maps to chromosome band 11q13 and coamplifies with the INT2 gene in human cancerAngiogenesis in the development of head and neck cancer and its inhibition by chemopreventive agents.The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors.The role of oncogenes in chemical carcinogenesisRole of proto-oncogene activation in carcinogenesis.The mouse homologue of hst/k-FGF: sequence, genome organization and location relative to int-2Mutation and expression of the p51 gene in human lung cancerGrowth factors in the gastrointestinal tractAIDS-associated Kaposi's sarcoma-derived cells in long-term culture express and synthesize smooth muscle alpha-actinAssociation of INT2/HST1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosisPossible dissociation of the heparin-binding and mitogenic activities of heparin-binding (acidic fibroblast) growth factor-1 from its receptor-binding activities by site-directed mutagenesis of a single lysine residue.Hst-1 (FGF-4) antisense oligonucleotides block murine limb development.A truncated K-sam product lacking the distal carboxyl-terminal portion provides a reduced level of autophosphorylation and greater resistance against induction of differentiationA retrovirus carrying the K-fgf oncogene induces diffuse meningeal tumors and soft-tissue fibrosarcomas.Expression of the K-fgf proto-oncogene is controlled by 3' regulatory elements which are specific for embryonal carcinoma cellsFibroblast growth factors, old kids on the new block.K-sam gene encodes secreted as well as transmembrane receptor tyrosine kinasePleiotropic function of FGF-4: its role in development and stem cells.Heparin-binding secretory transforming gene (hst) facilitates rat lactotrope cell tumorigenesis and induces prolactin gene transcription.Molecular pathology of the fibroblast growth factor family.The TPR-MET oncogenic rearrangement is present and expressed in human gastric carcinoma and precursor lesions.Growth factors as active participants in carcinogenesis: a perspective.Gene expression in prolactinomas: a systematic review.Expression and activation of the K-fgf oncogene.Fibroblasts induce expression of FGF4 in ovarian cancer stem-like cells/cancer-initiating cells and upregulate their tumor initiation capacity.FGF3/FGF4 amplification and multiple lung metastases in responders to sorafenib in hepatocellular carcinoma.
P2860
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P2860
Transforming gene from human stomach cancers and a noncancerous portion of stomach mucosa
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Transforming gene from human stomach cancers and a noncancerous portion of stomach mucosa
@ast
Transforming gene from human stomach cancers and a noncancerous portion of stomach mucosa
@en
type
label
Transforming gene from human stomach cancers and a noncancerous portion of stomach mucosa
@ast
Transforming gene from human stomach cancers and a noncancerous portion of stomach mucosa
@en
prefLabel
Transforming gene from human stomach cancers and a noncancerous portion of stomach mucosa
@ast
Transforming gene from human stomach cancers and a noncancerous portion of stomach mucosa
@en
P2093
P2860
P356
P1476
Transforming gene from human stomach cancers and a noncancerous portion of stomach mucosa
@en
P2093
Matsukawa S
Sakamoto H
Sekiguchi M
Sugimura T
P2860
P304
P356
10.1073/PNAS.83.11.3997
P407
P577
1986-06-01T00:00:00Z