Herpes simplex virus immediate early infected-cell polypeptide 4 binds to DNA and promotes transcription
about
Expression of varicella-zoster virus and herpes simplex virus in normal human trigeminal gangliaHost cell proteins bind to the cis-acting site required for virion-mediated induction of herpes simplex virus 1 alpha genesHerpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAsMutational analysis of varicella-zoster virus major immediate-early protein IE62.Proteomic analysis of the herpes simplex virus 1 virion protein 16 transactivator protein in infected cellsRepression of the herpes simplex virus 1 alpha 4 gene by its gene product (ICP4) within the context of the viral genome is conditioned by the distance and stereoaxial alignment of the ICP4 DNA binding site relative to the TATA boxLive covisualization of competing adeno-associated virus and herpes simplex virus type 1 DNA replication: molecular mechanisms of interaction.Transcriptional targeting of herpes simplex virus for cell-specific replication.Codons 262 to 490 from the herpes simplex virus ICP4 gene are sufficient to encode a sequence-specific DNA binding protein.Nucleotides within both proximal and distal parts of the consensus sequence are important for specific DNA recognition by the herpes simplex virus regulatory protein ICP4.The interaction of ICP4 with cell/infected-cell factors and its state of phosphorylation modulate differential recognition of leader sequences in herpes simplex virus DNA.Association of herpes simplex virus regulatory protein ICP4 with sequences spanning the ICP4 gene transcription initiation site.Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptidesGuanylylation and adenylylation of the alpha regulatory proteins of herpes simplex virus require a viral beta or gamma functionA second-site revertant of a defective herpes simplex virus ICP4 protein with restored regulatory activities and impaired DNA-binding propertiesAdenovirus E1A protein activates transcription of the E1A gene subsequent to transcription complex formation.Differences in the poly(ADP-ribosyl)ation patterns of ICP4, the herpes simplex virus major regulatory protein, in infected cells and in isolated nuclei.The ICP4 binding sites in the herpes simplex virus type 1 glycoprotein D (gD) promoter are not essential for efficient gD transcription during virus infectionHerpes simplex viruses with mutations in the gene encoding ICP0 are defective in gene expression.Mutational analysis of the ICP4 binding sites in the 5' transcribed noncoding domains of the herpes simplex virus 1 UL 49.5 gamma 2 geneICP4, the major regulatory protein of herpes simplex virus, shares features common to GTP-binding proteins and is adenylated and guanylated.Characterization of the DNA-binding properties of herpes simplex virus regulatory protein ICP4Functional relevance of specific interactions between herpes simplex virus type 1 ICP4 and sequences from the promoter-regulatory domain of the viral thymidine kinase gene.Regulation of cellular genes transduced by herpes simplex virus.ICP4-binding sites in the promoter and coding regions of the herpes simplex virus gD gene contribute to activation of in vitro transcription by ICP4Varicella-zoster virus infection of adult rat sensory neurons in vitro.DNA binding and gene regulation by the herpes simplex virus type 1 protein ICP4 and involvement of the TATA element.The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule.Differentiation and DNA contact points of host proteins binding at the cis site for virion-mediated induction of alpha genes of herpes simplex virus 1.Regulation of transcription in vitro from herpes simplex virus genes.The herpes simplex virus type 1 alpha protein ICP27 can act as a trans-repressor or a trans-activator in combination with ICP4 and ICP0.Role for DNA-protein interaction in activation of the herpes simplex virus glycoprotein D gene.Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4.Stages in the nuclear association of the herpes simplex virus transcriptional activator protein ICP4.Binding of the pseudorabies virus immediate-early protein to single-stranded DNA.Nucleotide sequence and temporal expression of a baculovirus regulatory geneExpression of a cellular gene cloned in herpes simplex virus: rabbit beta-globin is regulated as an early viral gene in infected fibroblasts.Requirements for activation of the herpes simplex virus glycoprotein C promoter in vitro by the viral regulatory protein ICP4.The initiator element in a herpes simplex virus type 1 late-gene promoter enhances activation by ICP4, resulting in abundant late-gene expressionRecruitment of herpes simplex virus type 1 transcriptional regulatory protein ICP4 into foci juxtaposed to ND10 in live, infected cells.
P2860
Q33565001-853FF428-407D-4B0C-99AA-8F94E33DA51EQ34584409-4659C8C3-6280-4363-AA50-877C476143E6Q34608970-CA45C948-6FBD-4F2D-A74C-6CF5985B9B66Q34746607-984D6D88-E49A-4A98-B67E-69F2DB659C77Q35586902-F31C3B17-918A-455D-B21C-F2FD3F0F9BB1Q35839047-44012F6D-7590-46FD-BEC2-24CDEFCB864FQ35857328-CF60A540-58E0-4491-8D60-C9E2DE112A34Q35887944-6742A4C5-FC85-404F-88FB-72D77ED9E332Q35907591-A5E2872A-6271-423C-82A8-BC890724CFA6Q35912368-EA02B444-748C-490A-A8D2-08B1B11ED9ADQ35921488-4E7655B7-F986-41D8-94E3-AC1A25F97172Q35941818-FF6332AD-20DE-4B04-9D85-BD876E2CD8FEQ36129181-D9069CA9-D3FF-4B93-B2C7-C4CAB31C004BQ36649833-F1F9CA91-51A1-4EB9-9BB8-D9B053D5172BQ36680161-901B33CD-9A91-4A8D-A7B3-98D55194BAA9Q36683439-4BDA5825-91FA-412D-B3BF-37227A131C87Q36684984-EA265DA9-39DC-40BC-ACA6-8ABE89055E9AQ36690288-69CB2926-3BAB-4ECD-91E9-CECA7FEFE9DFQ36697408-F3CA1FEB-1120-4BE8-B606-2E33011FD5ACQ36700188-2D33193E-18C5-4BFB-A3D3-81826AD10CC6Q36701500-FABDC816-A490-4E97-8BDD-6428864AC4A9Q36780682-EC855199-1682-48E5-9394-D68C72711AD5Q36806832-B79C180C-52B8-4D83-8544-BE67A621F333Q36827203-73071427-5045-49AF-982D-A4DD555459C9Q36828066-77A84256-C4E3-42A1-927F-D7BCB16D2392Q36829560-CB9DF07D-851C-4879-AC19-BC51F7DACFFAQ36830332-80E19D7D-A3A6-43D8-9F27-D60C5CFE06B5Q36831496-04A809C2-37AB-4475-ABF7-7077737A023EQ36865840-FB3D3CF4-7DC0-4670-91B8-9B2C68439038Q36870295-F63F9753-500A-4ED6-AAE4-C6221EF3689AQ36873481-F5D21573-0A4C-4DC2-B881-4C0648190DBFQ36874001-8D59B275-0ACF-4B87-A466-3159A35CCF91Q36875525-FCF5085E-8D0C-47E1-94F6-2123A939D2A2Q36884278-2BA474A0-628D-4323-8635-2A829AC1B831Q36888717-63786CAA-CED9-4803-B370-ECD3A9AD8A29Q36889543-8B47081A-D108-4BF0-ADBC-99BE19A2AA69Q36915558-ACD6A513-E60F-4011-96CF-43A10591D787Q38301836-88E65D0E-A3D0-4429-8198-68872E00FE57Q39682517-DFE91700-C902-44D9-A02B-117A06D34E4CQ39732581-185AB081-36EC-4CAE-B9BB-084723A7DA25
P2860
Herpes simplex virus immediate early infected-cell polypeptide 4 binds to DNA and promotes transcription
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Herpes simplex virus immediate ...... DNA and promotes transcription
@ast
Herpes simplex virus immediate ...... DNA and promotes transcription
@en
type
label
Herpes simplex virus immediate ...... DNA and promotes transcription
@ast
Herpes simplex virus immediate ...... DNA and promotes transcription
@en
prefLabel
Herpes simplex virus immediate ...... DNA and promotes transcription
@ast
Herpes simplex virus immediate ...... DNA and promotes transcription
@en
P2093
P2860
P356
P1476
Herpes simplex virus immediate ...... DNA and promotes transcription
@en
P2093
P2860
P304
P356
10.1073/PNAS.83.11.4016
P407
P577
1986-06-01T00:00:00Z