Guanylylation and adenylylation of the alpha regulatory proteins of herpes simplex virus require a viral beta or gamma function
about
Herpes simplex virus 1 regulatory protein ICP22 interacts with a new cell cycle-regulated factor and accumulates in a cell cycle-dependent fashion in infected cells.A novel cellular protein, p60, interacting with both herpes simplex virus 1 regulatory proteins ICP22 and ICP0 is modified in a cell-type-specific manner and Is recruited to the nucleus after infectionInfected cell protein 0 functional domains and their coordination in herpes simplex virus replicationPosttranslational processing of infected cell proteins 0 and 4 of herpes simplex virus 1 is sequential and reflects the subcellular compartment in which the proteins localizeCellular localization of the herpes simplex virus ICP0 protein dictates its ability to block IRF3-mediated innate immune responsesAssembly of infectious Herpes simplex virus type 1 virions in the absence of full-length VP22.The herpes simplex virus type 1 regulatory protein ICP27 is required for the prevention of apoptosis in infected human cells.Analysis of the phosphorylation sites of herpes simplex virus type 1 regulatory protein ICP27.Accumulation of herpes simplex virus type 1 early and leaky-late proteins correlates with apoptosis prevention in infected human HEp-2 cells.Herpes simplex virus ICP27 activation of stress kinases JNK and p38.Microtubule reorganization during herpes simplex virus type 1 infection facilitates the nuclear localization of VP22, a major virion tegument proteinHerpes simplex virus 1 alpha regulatory protein ICP0 functionally interacts with cellular transcription factor BMAL1.The cyclin-dependent kinase inhibitor roscovitine inhibits the transactivating activity and alters the posttranslational modification of herpes simplex virus type 1 ICP0.Mapping of functional regions in the amino-terminal portion of the herpes simplex virus ICP27 regulatory protein: importance of the leucine-rich nuclear export signal and RGG Box RNA-binding domain.NF-kappaB is required for apoptosis prevention during herpes simplex virus type 1 infectionSequence variation in the herpes simplex virus U(S)1 ocular virulence determinant.Role of ICP0 in the strategy of conquest of the host cell by herpes simplex virus 1The promoter and transcriptional unit of a novel herpes simplex virus 1 alpha gene are contained in, and encode a protein in frame with, the open reading frame of the alpha 22 geneAssociation of herpes simplex virus regulatory protein ICP22 with transcriptional complexes containing EAP, ICP4, RNA polymerase II, and viral DNA requires posttranslational modification by the U(L)13 proteinkinase.Casein kinase II specifically nucleotidylylates in vitro the amino acid sequence of the protein encoded by the alpha 22 gene of herpes simplex virus 1.Tyrosine phosphorylation of the herpes simplex virus type 1 regulatory protein ICP22 and a cellular protein which shares antigenic determinants with ICP22.Identification and characterization of the ICP22 protein of equine herpesvirus 1.Characterization of Marek's disease virus insertion and deletion mutants that lack US1 (ICP22 homolog), US10, and/or US2 and neighboring short-component open reading frames.Efficient quiescent infection of normal human diploid fibroblasts with wild-type herpes simplex virus type 1.Reconsideration of viral protein immunoblotting for differentiation of human herpes simplex viruses.The differential requirement for cyclin-dependent kinase activities distinguishes two functions of herpes simplex virus type 1 ICP0.Roles of p53 in herpes simplex virus 1 replication.Herpes simplex virus type 1 ICP0 protein does not accumulate in the nucleus of primary neurons in cultureHerpes simplex virus type 1 immediate-early gene expression is required for the induction of apoptosis in human epithelial HEp-2 cellsBroad-spectrum non-nucleoside inhibitors of human herpesvirusesA conserved carboxy-terminal domain in the major tegument structural protein VP22 facilitates virion packaging of a chimeric protein during productive herpes simplex virus 1 infection.
P2860
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P2860
Guanylylation and adenylylation of the alpha regulatory proteins of herpes simplex virus require a viral beta or gamma function
description
1993 nî lūn-bûn
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1993年の論文
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1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
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1993年论文
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1993年论文
@zh-cn
name
Guanylylation and adenylylatio ...... a viral beta or gamma function
@ast
Guanylylation and adenylylatio ...... a viral beta or gamma function
@en
type
label
Guanylylation and adenylylatio ...... a viral beta or gamma function
@ast
Guanylylation and adenylylatio ...... a viral beta or gamma function
@en
prefLabel
Guanylylation and adenylylatio ...... a viral beta or gamma function
@ast
Guanylylation and adenylylatio ...... a viral beta or gamma function
@en
P2860
P1433
P1476
Guanylylation and adenylylatio ...... a viral beta or gamma function
@en
P2093
P2860
P304
P407
P577
1993-07-01T00:00:00Z