The central melanocortin system and the integration of short- and long-term regulators of energy homeostasis.
about
The melanocortin system and energy balanceDesign, synthesis and biological evaluation of ligands selective for the melanocortin-3 receptorStructure-activity relationships of cyclic lactam analogues of alpha-melanocyte-stimulating hormone (alpha-MSH) targeting the human melanocortin-3 receptorGastrointestinal hormones regulating appetiteBalancing ovulation and anovulation: integration of the reproductive and energy balance axes by neuropeptidesNeuroendocrine regulation of appetitive ingestive behaviorA novel melanocortin-4 receptor mutation MC4R-P272L associated with severe obesity has increased propensity to be ubiquitinated in the ER in the face of correct foldingControl of energy balance by hypothalamic gene circuitry involving two nuclear receptors, neuron-derived orphan receptor 1 and glucocorticoid receptorA pharmacologically active monoclonal antibody against the human melanocortin-4 receptor: effectiveness after peripheral and central administrationWeight-independent effects of roux-en-Y gastric bypass on glucose homeostasis via melanocortin-4 receptors in mice and humans.Injection of Urocortin 3 into the ventromedial hypothalamus modulates feeding, blood glucose levels, and hypothalamic POMC gene expression but not the HPA axis.The hypophagic response to heat stress is not mediated by GPR109A or peripheral β-OH butyrateCritical role of arcuate Y4 receptors and the melanocortin system in pancreatic polypeptide-induced reduction in food intake in mice.Expression of ankyrin repeat and suppressor of cytokine signaling box protein 4 (Asb-4) in proopiomelanocortin neurons of the arcuate nucleus of mice produces a hyperphagic, lean phenotypeNPY neuron-specific Y2 receptors regulate adipose tissue and trabecular bone but not cortical bone homeostasis in miceNeuroendocrine circuits governing energy balance and stress regulation: functional overlap and therapeutic implicationsA potential role for hypothalamomedullary POMC projections in leptin-induced suppression of food intake.Effect of centrally administered C75, a fatty acid synthase inhibitor, on ghrelin secretion and its downstream effectsAn intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorptionMice with altered serotonin 2C receptor RNA editing display characteristics of Prader-Willi syndrome.Pro-opiomelanocortin gene transfer to the nucleus of the solitary track but not arcuate nucleus ameliorates chronic diet-induced obesityCorticosterone regulates synaptic input organization of POMC and NPY/AgRP neurons in adult miceThe CNS glucagon-like peptide-2 receptor in the control of energy balance and glucose homeostasisGlucocorticoids exacerbate obesity and insulin resistance in neuron-specific proopiomelanocortin-deficient mice.Identification of POMC exonic variants associated with substance dependence and body mass indexMelanocortin-4 receptor mutations and polymorphisms do not affect weight loss after bariatric surgery.Solid-phase peptide head-to-side chain cyclodimerization: discovery of C(2)-symmetric cyclic lactam hybrid α-melanocyte-stimulating hormone (MSH)/agouti-signaling protein (ASIP) analogues with potent activities at the human melanocortin receptorsAcute and repeated restraint differentially activate orexigenic pathways in the rat hypothalamus.Development of cyclic gamma-MSH analogues with selective hMC3R agonist and hMC3R/hMC5R antagonist activities.The alternative stimulatory G protein alpha-subunit XLalphas is a critical regulator of energy and glucose metabolism and sympathetic nerve activity in adult micemu-Opioid receptor stimulation in the nucleus accumbens elevates fatty tastant intake by increasing palatability and suppressing satiety signals.Effects of macrocycle size and rigidity on melanocortin receptor-1 and -5 selectivity in cyclic lactam alpha-melanocyte-stimulating hormone analogs.Gut hormones in the control of appetite.Brain-adipose tissue neural crosstalkThe melanocortin-4 receptor: physiology, pharmacology, and pathophysiology.Expression of fourteen novel obesity-related genes in Zucker diabetic fatty rats.Systematic Backbone Conformational Constraints on a Cyclic Melanotropin Ligand Leads to Highly Selective Ligands for Multiple Melanocortin Receptors.Leptin amplifies the action of thyrotropin-releasing hormone in the solitary nucleus: an in vitro calcium imaging study.Thematic review series: adipocyte biology. Sympathetic and sensory innervation of white adipose tissue.Melanocortin-4 receptor mRNA expressed in sympathetic outflow neurons to brown adipose tissue: neuroanatomical and functional evidence.
P2860
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P2860
The central melanocortin system and the integration of short- and long-term regulators of energy homeostasis.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The central melanocortin syste ...... ulators of energy homeostasis.
@ast
The central melanocortin syste ...... ulators of energy homeostasis.
@en
type
label
The central melanocortin syste ...... ulators of energy homeostasis.
@ast
The central melanocortin syste ...... ulators of energy homeostasis.
@en
prefLabel
The central melanocortin syste ...... ulators of energy homeostasis.
@ast
The central melanocortin syste ...... ulators of energy homeostasis.
@en
P356
P1433
P1476
The central melanocortin syste ...... ulators of energy homeostasis.
@en
P2093
Roger D Cone
P304
P356
10.1210/RP.59.1.395
P577
2004-01-01T00:00:00Z