Duplex DNA catalyzes the chemical rearrangement of a malondialdehyde deoxyguanosine adduct.
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Polyamines stimulate the formation of mutagenic 1,N2-propanodeoxyguanosine adducts from acetaldehydePyrimido[1,2-a]-purin-10(3H)-one, M1G, is less prone to artifact than base oxidation.3′-Intercalation of a N 2 -dG 1 R - trans - anti -Benzo[ c ]phenanthrene DNA Adduct in an Iterated (CG) 3 RepeatInsertion of dNTPs Opposite the 1, N 2 -Propanodeoxyguanosine Adduct by Sulfolobus solfataricus P2 DNA Polymerase IV † ‡Structural and Functional Analysis of Sulfolobus solfataricus Y-Family DNA Polymerase Dpo4-Catalyzed Bypass of the Malondialdehyde−Deoxyguanosine Adduct ,Structure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4: GUANINE N2,N2-DIMETHYL SUBSTITUTION PRODUCES INACTIVE AND MISCODING POLYMERASE COMPLEXESRing-Opening of the γ-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4Removal of oxygen free-radical-induced 5',8-purine cyclodeoxynucleosides from DNA by the nucleotide excision-repair pathway in human cellsNMR characterization of a DNA duplex containing the major acrolein-derived deoxyguanosine adduct gamma -OH-1,-N2-propano-2'-deoxyguanosine.Substituents on quinone methides strongly modulate formation and stability of their nucleophilic adducts.Creating context for the use of DNA adduct data in cancer risk assessment: II. Overview of methods of identification and quantitation of DNA damage.The 8,5'-cyclopurine-2'-deoxynucleosides: candidate neurodegenerative DNA lesions in xeroderma pigmentosum, and unique probes of transcription and nucleotide excision repair.Induction of frameshift and base pair substitution mutations by the major DNA adduct of the endogenous carcinogen malondialdehyde.Oxyradicals and DNA damage.Malondialdehyde adducts in DNA arrest transcription by T7 RNA polymerase and mammalian RNA polymerase II.Human DNA polymerase iota promotes replication through a ring-closed minor-groove adduct that adopts a syn conformation in DNA.Mechanism of repair of acrolein- and malondialdehyde-derived exocyclic guanine adducts by the α-ketoglutarate/Fe(II) dioxygenase AlkBReplication past a trans-4-hydroxynonenal minor-groove adduct by the sequential action of human DNA polymerases iota and kappa.Arrest of human mitochondrial RNA polymerase transcription by the biological aldehyde adduct of DNA, M1dG.Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein.Micromolar concentrations of hydrogen peroxide induce oxidative DNA lesions more efficiently than millimolar concentrations in mammalian cells.Reactive species and DNA damage in chronic inflammation: reconciling chemical mechanisms and biological fates.Inflammation and cancer: chemical approaches to mechanisms, imaging, and treatment.Vitamin E protects against lipid peroxidation and rescues tumorigenic phenotypes in cowden/cowden-like patient-derived lymphoblast cells with germline SDHx variants.Chemical structure and properties of interstrand cross-links formed by reaction of guanine residues with abasic sites in duplex DNAThe case for 8,5'-cyclopurine-2'-deoxynucleosides as endogenous DNA lesions that cause neurodegeneration in xeroderma pigmentosum.Site-specific synthesis of oligonucleotides containing malondialdehyde adducts of deoxyguanosine and deoxyadenosine via a postsynthetic modification strategy.The modulation of topoisomerase I-mediated DNA cleavage and the induction of DNA-topoisomerase I crosslinks by crotonaldehyde-derived DNA adducts.Stereospecific formation of interstrand carbinolamine DNA cross-links by crotonaldehyde- and acetaldehyde-derived alpha-CH3-gamma-OH-1,N2-propano-2'-deoxyguanosine adducts in the 5'-CpG-3' sequenceFormation of DNA-protein cross-links between gamma-hydroxypropanodeoxyguanosine and EcoRIChemical properties of oxopropenyl adducts of purine and pyrimidine nucleosides and their reactivity toward amino acid cross-link formation.Bulge migration of the malondialdehyde OPdG DNA adduct when placed opposite a two-base deletion in the (CpG)3 frameshift hotspot of the Salmonella typhimurium hisD3052 gene.Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.Replication, repair, and translesion polymerase bypass of N⁶-oxopropenyl-2'-deoxyadenosine.Chemistry and structural biology of DNA damage and biological consequencesOxidative stress--implications, source and its prevention.Acetaldehyde and the genome: beyond nuclear DNA adducts and carcinogenesis.Oxidative stress and mitochondrial dysfunction-linked neurodegenerative disorders.Molecular Mechanisms of Acetaldehyde-Mediated Carcinogenesis in Squamous Epithelium.Spectroscopic characterization of interstrand carbinolamine cross-links formed in the 5'-CpG-3' sequence by the acrolein-derived gamma-OH-1,N2-propano-2'-deoxyguanosine DNA adduct.
P2860
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P2860
Duplex DNA catalyzes the chemical rearrangement of a malondialdehyde deoxyguanosine adduct.
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Duplex DNA catalyzes the chemi ...... ldehyde deoxyguanosine adduct.
@ast
Duplex DNA catalyzes the chemi ...... ldehyde deoxyguanosine adduct.
@en
type
label
Duplex DNA catalyzes the chemi ...... ldehyde deoxyguanosine adduct.
@ast
Duplex DNA catalyzes the chemi ...... ldehyde deoxyguanosine adduct.
@en
prefLabel
Duplex DNA catalyzes the chemi ...... ldehyde deoxyguanosine adduct.
@ast
Duplex DNA catalyzes the chemi ...... ldehyde deoxyguanosine adduct.
@en
P2093
P2860
P356
P1476
Duplex DNA catalyzes the chemi ...... ldehyde deoxyguanosine adduct.
@en
P2093
J P Weisenseel
L J Marnett
N C Schnetz-Boutaud
P2860
P304
P356
10.1073/PNAS.96.12.6615
P407
P577
1999-06-01T00:00:00Z