The modulation of topoisomerase I-mediated DNA cleavage and the induction of DNA-topoisomerase I crosslinks by crotonaldehyde-derived DNA adducts.
about
Biochemical characterization of human tyrosyl-DNA phosphodiesterase 2 (TDP2/TTRAP): a Mg(2+)/Mn(2+)-dependent phosphodiesterase specific for the repair of topoisomerase cleavage complexesGenome-wide analysis of novel splice variants induced by topoisomerase I poisoning shows preferential occurrence in genes encoding splicing factors.Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2).γ-Hydroxy-1,N2-propano-2'-deoxyguanosine DNA adduct conjugates the N-terminal amine of the KWKK peptide via a carbinolamine linkage.Identification of novel PARP inhibitors using a cell-based TDP1 inhibitory assay in a quantitative high-throughput screening platform.Biochemical assays for the discovery of TDP1 inhibitorsMus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes.Expression profiling identifies epoxy anthraquinone derivative as a DNA topoisomerase inhibitor.Transcription poisoning by Topoisomerase I is controlled by gene length, splice sites, and miR-142-3pChemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.DNA cleavage assay for the identification of topoisomerase I inhibitors.
P2860
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P2860
The modulation of topoisomerase I-mediated DNA cleavage and the induction of DNA-topoisomerase I crosslinks by crotonaldehyde-derived DNA adducts.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The modulation of topoisomeras ...... naldehyde-derived DNA adducts.
@ast
The modulation of topoisomeras ...... naldehyde-derived DNA adducts.
@en
type
label
The modulation of topoisomeras ...... naldehyde-derived DNA adducts.
@ast
The modulation of topoisomeras ...... naldehyde-derived DNA adducts.
@en
prefLabel
The modulation of topoisomeras ...... naldehyde-derived DNA adducts.
@ast
The modulation of topoisomeras ...... naldehyde-derived DNA adducts.
@en
P2093
P2860
P356
P1476
The modulation of topoisomeras ...... naldehyde-derived DNA adducts.
@en
P2093
Albena Kozekova
Carmelo J Rizzo
Michael P Stone
Thomas S Dexheimer
P2860
P304
P356
10.1093/NAR/GKN334
P407
P50
P577
2008-06-10T00:00:00Z