Interferons induce tyrosine phosphorylation of the eIF2alpha kinase PKR through activation of Jak1 and Tyk2.
about
Protein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon responsePERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation.Baseline gene expression signatures in monocytes from multiple sclerosis patients treated with interferon-betaEndoplasmic reticulum stress in disorders of myelinating cells.West Nile virus infection does not induce PKR activation in rodent cells.Cooperative roles of fish protein kinase containing Z-DNA binding domains and double-stranded RNA-dependent protein kinase in interferon-mediated antiviral response.Association of chronic alcohol consumption and increased susceptibility to and pathogenic effects of pulmonary infection with respiratory syncytial virus in mice.The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development.MicroRNA regulation of mitochondrial and ER stress signaling pathways: implications for lipoprotein metabolism in metabolic syndrome.A piscine birnavirus induces inhibition of protein synthesis in CHSE-214 cells primarily through the induction of eIF2α phosphorylationThe non-steroidal anti-inflammatory drug indomethacin activates the eIF2α kinase PKR, causing a translational block in human colorectal cancer cells.Resistance to the proapoptotic effects of interferon-gamma on melanoma cells used in patient-specific dendritic cell immunotherapy is associated with improved overall survival.Tyrosine kinase 2 controls IL-1ß production at the translational level.Tumor suppression by PTEN requires the activation of the PKR-eIF2alpha phosphorylation pathwayInterferon-gamma bolsters CD95/Fas-mediated apoptosis of astroglioma cells.Modulation of the eukaryotic initiation factor 2 alpha-subunit kinase PERK by tyrosine phosphorylation.Proteomic analysis of filaggrin deficiency identifies molecular signatures characteristic of atopic eczema.
P2860
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P2860
Interferons induce tyrosine phosphorylation of the eIF2alpha kinase PKR through activation of Jak1 and Tyk2.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Interferons induce tyrosine ph ...... h activation of Jak1 and Tyk2.
@ast
Interferons induce tyrosine ph ...... h activation of Jak1 and Tyk2.
@en
type
label
Interferons induce tyrosine ph ...... h activation of Jak1 and Tyk2.
@ast
Interferons induce tyrosine ph ...... h activation of Jak1 and Tyk2.
@en
prefLabel
Interferons induce tyrosine ph ...... h activation of Jak1 and Tyk2.
@ast
Interferons induce tyrosine ph ...... h activation of Jak1 and Tyk2.
@en
P2093
P2860
P356
P1433
P1476
Interferons induce tyrosine ph ...... h activation of Jak1 and Tyk2.
@en
P2093
Andrew Hoi-Tao Wong
Antonis E Koromilas
Dionissios Baltzis
Jennifer F Raven
Qiaozhu Su
Suiyang Li
P2860
P304
P356
10.1038/SJ.EMBOR.7400891
P577
2007-02-09T00:00:00Z