Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.
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DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88Calcium phosphate nanoparticles-based systems for siRNA deliverySmelling the roses and seeing the light: gene therapy for ciliopathiesMechanisms of age-related macular degenerationProtection of retina by αB crystallin in sodium iodate induced retinal degenerationProgress toward in vivo use of siRNAs-IIAlu mobile elements: from junk DNA to genomic gemsEffects of Pathogenic Variations in the Human Rhodopsin Gene (hRHO) on the Predicted Accessibility for a Lead Candidate Ribozyme.The Immune System and AMDHistamine H4 receptor as a new therapeutic target for choroidal neovascularization in age-related macular degenerationA novel protective role for the innate immunity Toll-Like Receptor 3 (TLR3) in the retina via Stat3HTRA1 (high temperature requirement A serine peptidase 1) gene is transcriptionally regulated by insertion/deletion nucleotides located at the 3' end of the ARMS2 (age-related maculopathy susceptibility 2) gene in patients with age-related macular dDevelopment of gene therapy for treatment of age-related macular degeneration.Plasma-activated medium suppresses choroidal neovascularization in mice: a new therapeutic concept for age-related macular degeneration.Association of toll-like receptor 3 polymorphism rs3775291 with age-related macular degeneration: a systematic review and meta-analysisPhotoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal.Retinal pigment epithelium (RPE) exosomes contain signaling phosphoproteins affected by oxidative stress.Identification of age-related macular degeneration related genes by applying shortest path algorithm in protein-protein interaction network.Immunology of age-related macular degenerationIn vitro and in vivo efficacy of SYL040012, a novel siRNA compound for treatment of glaucoma.RNA interference trigger variants: getting the most out of RNA for RNA interference-based therapeuticsGene therapy in animal models of autosomal dominant retinitis pigmentosaNovel siRNA delivery strategy: a new "strand" in CNS translational medicine?Small RNA drugs for prion disease: a new frontier.Small-interfering RNAs (siRNAs) as a promising tool for ocular therapy.Activated Retinal Pigment Epithelium, an Optical Coherence Tomography Biomarker for Progression in Age-Related Macular Degeneration.Adeno-associated virus type 8 vector-mediated expression of siRNA targeting vascular endothelial growth factor efficiently inhibits neovascularization in a murine choroidal neovascularization modelDiscriminating self from non-self in nucleic acid sensing.Genome editing: the breakthrough technology for inherited retinal disease?Toll-like receptor 3 signalling mediates angiogenic response upon shock wave treatment of ischaemic muscle.Toll-like receptor 3 (TLR3) protects retinal pigmented epithelium (RPE) cells from oxidative stress through a STAT3-dependent mechanism.Gene expression regulation in retinal pigment epithelial cells induced by viral RNA and viral/bacterial DNA.Inhibition of choroidal fibrovascular membrane formation by new class of RNA interference therapeutic agent targeting periostin.Therapeutic Effect of Novel Single-Stranded RNAi Agent Targeting Periostin in Eyes with Retinal NeovascularizationThe retinal pigment epithelium (RPE) induces FasL and reduces iNOS and Cox2 in primary monocytes.Allele-specific siRNA silencing for the common keratin 12 founder mutation in Meesmann epithelial corneal dystrophy.cGAS drives noncanonical-inflammasome activation in age-related macular degeneration.Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway.Stimulation of TLR3 triggers release of lysosomal ATP in astrocytes and epithelial cells that requires TRPML1 channels.
P2860
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P2860
Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.
@ast
Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.
@en
type
label
Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.
@ast
Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.
@en
prefLabel
Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.
@ast
Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.
@en
P2093
P2860
P356
P1433
P1476
Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3.
@en
P2093
Alexander D Blandford
Balamurali K Ambati
Benjamin J Fowler
Bradley D Gelfand
Hiroki Kaneko
Hiroko Terasaki
Jayakrishna Ambati
Judit Z Baffi
Mark E Kleinman
Mineo Kondo
P2860
P304
P356
10.1038/MT.2011.212
P577
2011-10-11T00:00:00Z