Polymorphisms of the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study.
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Chibby promotes adipocyte differentiation through inhibition of beta-catenin signalingThe obesity of boneBone and the regulation of global energy balanceWnt-Lrp5 signaling regulates fatty acid metabolism in the osteoblast.Islet specific Wnt activation in human type II diabetes.Oxidative stress: Biomarkers and novel therapeutic pathways.New strategies for Alzheimer's disease and cognitive impairment.Genetic predisposition for femoral neck stress fractures in military conscripts.Dose-dependent effect of estrogen suppresses the osteo-adipogenic transdifferentiation of osteoblasts via canonical Wnt signaling pathway.Diabetes mellitus: channeling care through cellular discoveryReplication study of candidate genes/loci associated with osteoporosis based on genome-wide screening.SOST and DKK: Antagonists of LRP Family Signaling as Targets for Treating Bone Disease.Wnt1 neuroprotection translates into improved neurological function during oxidant stress and cerebral ischemia through AKT1 and mitochondrial apoptotic pathways.Polymorphisms of the tumor necrosis factor-alpha receptor 2 gene are associated with obesity phenotypes among 405 Caucasian nuclear families.Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.Novel avenues of drug discovery and biomarkers for diabetes mellitus.The impact of LRP5 polymorphism (rs556442) on calcium homeostasis, bone mineral density, and body composition in Iranian children.Association of Canonical Wnt/β-Catenin Pathway and Type 2 Diabetes: Genetic Epidemiological Study in Han Chinese.Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5).Genome wide association study: searching for genes underlying body mass index in the ChineseDefective Wnt Signaling: A Potential Contributor to Cardiometabolic Disease?The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspectiveNovel directions for diabetes mellitus drug discoverySecond-generation antisense oligonucleotides against β-catenin protect mice against diet-induced hepatic steatosis and hepatic and peripheral insulin resistance.Triple play: promoting neurovascular longevity with nicotinamide, WNT, and erythropoietin in diabetes mellitus.The Wnt signaling pathway: aging gracefully as a protectionist?Erythropoietin: elucidating new cellular targets that broaden therapeutic strategiesMechanistic insights into diabetes mellitus and oxidative stressErythropoietin and oxidative stress.Wnt/beta-catenin signaling in adipogenesis and metabolism.Adipose- and muscle-derived Wnts trigger pancreatic β-cell adaptation to systemic insulin resistanceVascular injury during elevated glucose can be mitigated by erythropoietin and Wnt signaling.Association of LRP5 gene polymorphism with type 2 diabetes mellitus and osteoporosis in postmenopausal women.No association between LRP5 gene polymorphisms and bone and obesity phenotypes in Chinese male-offspring nuclear families.WNT signaling: an emerging mediator of cancer cell metabolism?The influence of Leucine-rich amelogenin peptide on MSC fate by inducing Wnt10b expression.Activation of canonical wingless-type MMTV integration site family (Wnt) signaling in mature adipocytes increases beta-catenin levels and leads to cell dedifferentiation and insulin resistance.Association of type 2 diabetes mellitus with the interaction between low-density lipoprotein receptor-related protein 5 (LRP5) polymorphisms and overweight and obesity in rural Chinese adults.Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism.COL18A1 is highly expressed during human adipocyte differentiation and the SNP c.1136C > T in its "frizzled" motif is associated with obesity in diabetes type 2 patients.
P2860
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P2860
Polymorphisms of the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with obesity phenotypes in a large family-based association study.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Polymorphisms of the low-densi ...... amily-based association study.
@ast
Polymorphisms of the low-densi ...... amily-based association study.
@en
type
label
Polymorphisms of the low-densi ...... amily-based association study.
@ast
Polymorphisms of the low-densi ...... amily-based association study.
@en
prefLabel
Polymorphisms of the low-densi ...... amily-based association study.
@ast
Polymorphisms of the low-densi ...... amily-based association study.
@en
P2093
P2860
P356
P1476
Polymorphisms of the low-densi ...... amily-based association study.
@en
P2093
Dong-hai Xiong
Lan-juan Zhao
Robert R Recker
Yan-fang Guo
P2860
P304
P356
10.1136/JMG.2006.041715
P407
P577
2006-05-24T00:00:00Z