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Role of Receptor Tyrosine Kinase Signaling in Renal FibrosisEGFR signaling in renal fibrosisA novel role for c-Myc in G protein-coupled receptor kinase 4 (GRK4) transcriptional regulation in human kidney proximal tubule cells.Central role of the exchange factor GEF-H1 in TNF-α-induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells.Epidermal growth factor receptor inhibition slows progression of diabetic nephropathy in association with a decrease in endoplasmic reticulum stress and an increase in autophagyEGFR inhibition attenuates diabetic nephropathy through decreasing ROS and endoplasmic reticulum stress.Epidermal Growth Factor Receptor Transactivation: Mechanisms, Pathophysiology, and Potential Therapies in the Cardiovascular SystemBlocking the class I histone deacetylase ameliorates renal fibrosis and inhibits renal fibroblast activation via modulating TGF-beta and EGFR signalingProtein-bound uremic toxins induce tissue remodeling by targeting the EGF receptorVascular induction of a disintegrin and metalloprotease 17 by angiotensin II through hypoxia inducible factor 1α.EGF receptor deletion in podocytes attenuates diabetic nephropathy.Role of epidermal growth factor receptor and endoplasmic reticulum stress in vascular remodeling induced by angiotensin II.Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury.Characterization of a Decapentapletic Gene (AccDpp) from Apis cerana cerana and Its Possible Involvement in Development and Response to Oxidative Stress.PTEN loss defines a TGF-β-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis.Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injurySimultaneous deletion of Bax and Bak is required to prevent apoptosis and interstitial fibrosis in obstructive nephropathyPredicting diabetes mellitus genes via protein-protein interaction and protein subcellular localization information.EGF Receptor Inhibition Alleviates Hyperuricemic Nephropathy.Role of epidermal growth factor receptor in acute and chronic kidney injury.The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling PathwaysEarly growth response genes signaling supports strong paracrine capability of mesenchymal stem cells.mVps34 deletion in podocytes causes glomerulosclerosis by disrupting intracellular vesicle trafficking.Blocking rpS6 Phosphorylation Exacerbates Tsc1 Deletion-Induced Kidney GrowthSrc inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis.Interaction of the EGF Receptor and the Hippo Pathway in the Diabetic Kidney.Sustained activation of EGFR triggers renal fibrogenesis after acute kidney injury.Epidermal growth factors in the kidney and relationship to hypertension.HDAC inhibitors in kidney development and disease.ADAM17 substrate release in proximal tubule drives kidney fibrosisEGFR mediates hyperlipidemia-induced renal injury via regulating inflammation and oxidative stress: the detrimental role and mechanism of EGFR activation.Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling.Survivin mediates renal proximal tubule recovery from AKI.Kidney-specific transposon-mediated gene transfer in vivo.An update on the pathomechanisms and future therapies of Alport syndrome.Molecular targets for treatment of kidney fibrosis.Understanding the origin, activation and regulation of matrix-producing myofibroblasts for treatment of fibrotic disease.Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1.Renal allograft fibrosis: biology and therapeutic targets.Novel EGFR inhibitors attenuate cardiac hypertrophy induced by angiotensin II.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
EGFR signaling promotes TGFβ-dependent renal fibrosis
@ast
EGFR signaling promotes TGFβ-dependent renal fibrosis
@en
type
label
EGFR signaling promotes TGFβ-dependent renal fibrosis
@ast
EGFR signaling promotes TGFβ-dependent renal fibrosis
@en
prefLabel
EGFR signaling promotes TGFβ-dependent renal fibrosis
@ast
EGFR signaling promotes TGFβ-dependent renal fibrosis
@en
P2093
P2860
P356
P1476
EGFR signaling promotes TGFβ-dependent renal fibrosis
@en
P2093
David Plieth
Eric G Neilson
Jian-Kang Chen
Jianchun Chen
Kojiro Nagai
Mingqi Tan
Raymond C Harris
Tang-Cheng Lee
P2860
P304
P356
10.1681/ASN.2011070645
P577
2011-11-17T00:00:00Z