Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization. - Wikidata - awgldk - TriplyDB

Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization.

Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization.

http://www.wikidata.org/entity/Q35720592

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Proteinase-activated receptor-2 mediated inhibition of TNFalpha-stimulated JNK activation - A novel paradigm for G(q/11) linked GPCRs Cowhage-evoked itch is mediated by a novel cysteine protease: a ligand of protease-activated receptors Cytoprotective-selective activated protein C therapy for ischaemic stroke Enteric bacterial proteases in inflammatory bowel disease- pathophysiology and clinical implications Crystal structures of murine thrombin in complex with the extracellular fragments of murine protease-activated receptors PAR3 and PAR4 Thrombin and vascular inflammation PAR-3 knockdown enhances adhesion rate of PANC-1 cells via increased expression of integrinαv and E-cadherin.Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis.Differential signaling by protease-activated receptors: implications for therapeutic targeting.The G protein betagamma subunit mediates reannealing of adherens junctions to reverse endothelial permeability increase by thrombin.Evaluation on potential contributions of protease activated receptors related mediators in allergic inflammation.Hyaluronic Acid binding protein 2 is a novel regulator of vascular integrity Modulation of expression of innate immunity markers CXCL5/ENA-78 and CCL20/MIP3alpha by protease-activated receptors (PARs) in human gingival epithelial cells Signal transduction by protease-activated receptors Thrombin regulates the metastatic potential of human rhabdomyosarcoma cells: distinct role of PAR1 and PAR3 signaling.The specific monomer/dimer equilibrium of the corticotropin-releasing factor receptor type 1 is established in the endoplasmic reticulum Inhibiting protease-activated receptor 4 limits myocardial ischemia/reperfusion injury in rat hearts by unmasking adenosine signaling.Allosteric modulation of protease-activated receptor signaling.Noncanonical PAR3 activation by factor Xa identifies a novel pathway for Tie2 activation and stabilization of vascular integrity.Calcium mobilization and protein kinase C activation downstream of protease activated receptor 4 (PAR4) is negatively regulated by PAR3 in mouse platelets Streptococcal SpeB cleaved PAR-1 suppresses ERK phosphorylation and blunts thrombin-induced platelet aggregation.Proteases display biased agonism at protease-activated receptors: location matters!Activated protein C: biased for translation.We can do it together: PAR1/PAR2 heterodimer signaling in VSMCs Characterization of thrombin-bound dabigatran effects on protease-activated receptor-1 expression and signaling in vitro.Modulation of protease-activated receptor expression by Porphyromonas gingivalis in human gingival epithelial cells.Allosteric Activation of a G Protein-coupled Receptor with Cell-penetrating Receptor Mimetics Mapping human protease-activated receptor 4 (PAR4) homodimer interface to transmembrane helix 4 Kallikrein 6 is a novel molecular trigger of reactive astrogliosis.Cathepsin K induces platelet dysfunction and affects cell signaling in breast cancer - molecularly distinct behavior of cathepsin K in breast cancer.Protease-activated receptor-1 cleaved at R46 mediates cytoprotective effects.Interface between hemostasis and adaptive immunity Diverse functional outcomes of Plasmodium falciparum ligation of EPCR: potential implications for malarial pathogenesis.Protease-activated receptors (PARs)--biology and role in cancer invasion and metastasis.Thrombin.Twist-mediated Epithelial-mesenchymal Transition Promotes Breast Tumor Cell Invasion via Inhibition of Hippo Pathway.A day in the life of a G protein-coupled receptor: the contribution to function of G protein-coupled receptor dimerization.Gastrointestinal roles for proteinase-activated receptors in health and disease.Mechanisms of anticoagulant and cytoprotective actions of the protein C pathway.Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more.

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P2860

Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization.

http://www.wikidata.org/entity/Q35720592

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization.

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Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization.

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type

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Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization.

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Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization.

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prefLabel

Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization.

@ast

Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization.

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Proceedings of the National Academy of Sciences of the United States of America

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Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization.

@en

P2093

Asrar B Malik

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Joseph N McLaughlin

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Myla M Patterson

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P2860

Protease-activated receptor 3 is a second thrombin receptor in humans

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

PAR3 is a cofactor for PAR4 activation by thrombin

Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

Cardiovascular responses mediated by protease-activated receptor-2 (PAR-2) and thrombin receptor (PAR-1) are distinguished in mice deficient in PAR-2 or PAR-1

Structure-based analysis of GPCR function: evidence for a novel pentameric assembly between the dimeric leukotriene B4 receptor BLT1 and the G-protein.

Requirement for Ca2+ signaling in the mechanism of thrombin-induced increase in endothelial permeability.

Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1.

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5662-5667

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