alpha-synuclein promotes mitochondrial deficit and oxidative stress
about
alpha-Synuclein and neuronal cell deathThe role of oxidative stress in Parkinson's diseaseNeuroprotective and anti-inflammatory properties of a coffee component in the MPTP model of Parkinson's diseasemicroRNAs: Emerging Targets Regulating Oxidative Stress in the Models of Parkinson's DiseaseParkinson's Disease: The Mitochondria-Iron LinkThe Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative DiseasesNeuronal response in Alzheimer's and Parkinson's disease: the effect of toxic proteins on intracellular pathwaysNovel subcellular localization for α-synuclein: possible functional consequencesExploring myelin dysfunction in multiple system atrophyPathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body diseaseCommon defects of mitochondria and iron in neurodegeneration and diabetes (MIND): a paradigm worth exploringC-Terminal Tyrosine Residue Modifications Modulate the Protective Phosphorylation of Serine 129 of α-Synuclein in a Yeast Model of Parkinson's Disease.The phosphorylation of α-synuclein: development and implication for the mechanism and therapy of the Parkinson's diseaseExtracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegansDegradative organelles containing mislocalized alpha-and beta-synuclein proliferate in presenilin-1 null neuronsTotal and mitochondrial nitrosative stress, decreased brain-derived neurotrophic factor (BDNF) levels and glutamate uptake, and evidence of endoplasmic reticulum stress in the hippocampus of vitamin A-treated ratsPGC-1{alpha} and PGC-1{beta} regulate mitochondrial density in neuronsDisease-toxicant interactions in Parkinson's disease neuropathologyA mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicineMitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by ParkinClearance and phosphorylation of alpha-synuclein are inhibited in methionine sulfoxide reductase a null yeast cells.New insights into mitochondrial structure during cell death.Mitochondrial permeability transition pore regulates Parkinson's disease development in mutant α-synuclein transgenic mice.alpha-Synuclein affects the MAPK pathway and accelerates cell death.Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protectionIdentification of novel proteins affected by rotenone in mitochondria of dopaminergic cellsGenes associated with Parkinson syndrome.Mitochondrial DNA and primary mitochondrial dysfunction in Parkinson's disease.Insights into the effects of alpha-synuclein expression and proteasome inhibition on glutathione metabolism through a dynamic in silico model of Parkinson's disease: validation by cell culture data.Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein.The transgenic overexpression of alpha-synuclein and not its related pathology associates with complex I inhibition.Reduced expression of peroxisome-proliferator activated receptor gamma coactivator-1alpha enhances alpha-synuclein oligomerization and down regulates AKT/GSK3beta signaling pathway in human neuronal cells that inducibly express alpha-synuclein.Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases.Mitochondrial dysfunction in the striatum of aged chronic mouse model of Parkinson's disease.Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's diseasebeta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease.Regulation of Weibel-Palade body exocytosis by alpha-synuclein in endothelial cells.Soluble, prefibrillar α-synuclein oligomers promote complex I-dependent, Ca2+-induced mitochondrial dysfunction.Genetic factors and manganese-induced neurotoxicity.Baicalein reduces E46K alpha-synuclein aggregation in vitro and protects cells against E46K alpha-synuclein toxicity in cell models of familiar Parkinsonism.
P2860
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P2860
alpha-synuclein promotes mitochondrial deficit and oxidative stress
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
alpha-synuclein promotes mitochondrial deficit and oxidative stress
@ast
alpha-synuclein promotes mitochondrial deficit and oxidative stress
@en
type
label
alpha-synuclein promotes mitochondrial deficit and oxidative stress
@ast
alpha-synuclein promotes mitochondrial deficit and oxidative stress
@en
prefLabel
alpha-synuclein promotes mitochondrial deficit and oxidative stress
@ast
alpha-synuclein promotes mitochondrial deficit and oxidative stress
@en
P2093
P2860
P1476
alpha-synuclein promotes mitochondrial deficit and oxidative stress
@en
P2093
E Rockenstein
M Hashimoto
T Takenouchi
P2860
P304
P356
10.1016/S0002-9440(10)64553-1
P407
P577
2000-08-01T00:00:00Z