Anaesthetic potencies of primary alkanols: implications for the molecular dimensions of the anaesthetic site
about
General anaesthetic actions on ligand-gated ion channelsThe Role of Multiple Hydrogen-Bonding Groups in Specific Alcohol Binding Sites in Proteins: Insights from Structural Studies of LUSHStraight-chain alcohols exhibit a cutoff in potency for the inhibition of recombinant glutamate receptor subunitsG-protein-coupled inwardly rectifying potassium channels are targets of alcohol actionVolatile anesthetics affect the morphology of rat glioma C6 cells via RhoA, ERK, and Akt activationMechanisms of inhibition of CaV3.1 T-type calcium current by aliphatic alcoholsMechanisms of inhibition of T-type calcium current in the reticular thalamic neurons by 1-octanol: implication of the protein kinase C pathwayA transmembrane site determines sensitivity of neuronal nicotinic acetylcholine receptors to general anesthetics.Direct antagonism of ethanol's effects on GABA(A) receptors by increased atmospheric pressure.Different distribution of fluorinated anesthetics and nonanesthetics in model membrane: a 19F NMR study.Molecular targets and mechanisms for ethanol action in glycine receptorsTrans-unsaturated lipid dynamics: modulation of dielaidoylphosphatidylcholine acyl chain motion by ethanolAcetylcholine and alcohol sensitivity of neuronal nicotinic acetylcholine receptors: mutations in transmembrane domains.p-Trifluoromethyldiazirinyl-etomidate: a potent photoreactive general anesthetic derivative of etomidate that is selective for ligand-gated cationic ion channels.Structural basis for alcohol modulation of a pentameric ligand-gated ion channelAlcohol's effects on lipid bilayer properties.Butanol isomers exert distinct effects on voltage-gated calcium channel currents and thus catecholamine secretion in adrenal chromaffin cells.The TM2 6' position of GABA(A) receptors mediates alcohol inhibitionCharacterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols.Effects of 5-HT uptake inhibitors, agonists and antagonists on the burying of harmless objects by mice; a putative test for anxiolytic agents.Enhancement of homomeric glycine receptor function by long-chain alcohols and anaestheticsProbing the molecular dimensions of general anaesthetic target sites in tadpoles (Xenopus laevis) and model systems using cycloalcoholsMolecular properties important for inhaled anesthetic action on human 5-HT3A receptors.Modulation of human 5-hydroxytryptamine type 3AB receptors by volatile anesthetics and n-alcohols.Molecular features of an alcohol binding site in a neuronal potassium channel.Identification of an alcohol binding site in the first cysteine-rich domain of protein kinase Cdeltap-(4-Azipentyl)propofol: a potent photoreactive general anesthetic derivative of propofol.Slowly inactivating component of Na+ current in peri-somatic region of hippocampal CA1 pyramidal neuronsn-Alcohols inhibit voltage-gated Na+ channels expressed in Xenopus oocytes.Functional characterization of neurotransmitter activation and modulation in a nematode model ligand-gated ion channel.Anesthetic-like modulation of receptor function by surfactants: a test of the interfacial theory of anesthesiaEthanol's molecular targetsIdentification of a fluorescent general anesthetic, 1-aminoanthracene.Modulation of the general anesthetic sensitivity of a protein: a transition between two forms of firefly luciferase.Mutations of gamma-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor?Seeking structural specificity: direct modulation of pentameric ligand-gated ion channels by alcohols and general anesthetics.Alcohol-binding sites in distinct brain proteins: the quest for atomic level resolution.Is there a specific receptor for anesthetics? Contrary effects of alcohols and fatty acids on phase transition and bioluminescence of firefly luciferase.Mapping General Anesthetic Sites in Heteromeric γ-Aminobutyric Acid Type A Receptors Reveals a Potential For Targeting Receptor Subtypes.Differential effects of ethanol on glycine uptake mediated by the recombinant GLYT1 and GLYT2 glycine transporters.
P2860
Q24595524-DB42FC37-C06A-439B-A811-EADD849630DDQ27649736-E4484F3A-D2D2-46B2-9435-0F5BEA25959EQ28367866-A88B63C1-83C0-44C9-A424-AED09F9D7DE8Q28376789-004828C5-F794-4AEB-885B-B5047F5935EDQ28578598-0DD3C9E7-F77F-4ED7-AF92-A57185889308Q30431664-BEB10E3E-0F0E-4A9A-A15F-FDDC67F0E13DQ30433716-E80704D0-C420-46C2-917B-9C4CB97443B7Q31446928-6C46FC0B-42A0-4775-AC05-25005B80E660Q33488071-48225C7C-FB76-471D-B95E-CF7D8015A92AQ33915268-94585AB4-C112-4F17-8EAD-50CC07DDE5DBQ33936421-B8D1F4FE-F0D6-4738-92C8-8A9327F62F02Q34019858-12774F23-D5BA-4CC5-927B-E36A1B0ACB92Q34530041-0A39DED1-563B-42AE-A1D5-FC8D8843D2CDQ35052026-D6EBC52A-6BA4-4C6D-AE8B-E66F2CA5C269Q35122953-78A32494-4945-4CAB-8A52-4B1E5F34A571Q35218338-B5A699AE-B5B9-4990-867A-D84F8A1E792CQ35294357-784A3290-A7B4-4788-8F66-364803F486A5Q35688528-F90C0A8A-AF0F-4D92-8DF2-19DA4B0D1810Q35688558-2F4E090E-E5B4-45C6-8B02-B10E279A7DF8Q35871873-8F484A72-EF7B-477A-A2DD-7D379064A7B8Q35884602-1B201AA8-2B8D-4D2B-84BF-8FA719BCEB7CQ35888584-7FD91AAE-E79E-40CC-86A6-20C093772484Q35942648-A7FA0F4B-552B-41B3-AF86-8890C364DA81Q35993002-87C8304D-D3C2-43DE-8C6A-CEC211C3019DQ36417172-7702D0CD-5010-4D37-A9A0-3C338C03D7F2Q36458611-9AAAB43B-38B8-4187-B8C8-5D8905DD0FD8Q36634576-762D8580-0B8B-45CB-A25A-8CB0BD6B9055Q36700341-D744DBDC-5345-4CCF-890E-19BE54CBA65EQ36953656-D29DB941-F4CB-490F-B5A2-CEA896B2E06FQ37075331-CD54230A-1C52-42C8-B9BF-BF5DEA66FB18Q37157447-FB51A52F-A5A0-4778-966B-2A3F51CB2B01Q37165668-513CC1E5-0C9E-41D4-A6C3-6D81712B2203Q37167655-5A6BC496-A649-4780-8E5E-D9835568EA77Q37360976-83949575-5261-449A-9812-68295E6C267AQ37438358-C76DC3E9-5275-4A57-9023-552A66808E10Q37680855-FAC15EB0-9FA5-419D-A351-4135420BBDDCQ37890000-283FF7BB-85A9-46D5-9C21-D08E78230701Q38550955-810FB630-FF07-46D4-9D0E-15461CF7A457Q38831924-3B944485-7939-438D-A716-C428A70872FCQ40899175-7E84DF60-85E0-4DDA-8C01-C162C7190A4E
P2860
Anaesthetic potencies of primary alkanols: implications for the molecular dimensions of the anaesthetic site
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Anaesthetic potencies of prima ...... nsions of the anaesthetic site
@ast
Anaesthetic potencies of prima ...... nsions of the anaesthetic site
@en
type
label
Anaesthetic potencies of prima ...... nsions of the anaesthetic site
@ast
Anaesthetic potencies of prima ...... nsions of the anaesthetic site
@en
prefLabel
Anaesthetic potencies of prima ...... nsions of the anaesthetic site
@ast
Anaesthetic potencies of prima ...... nsions of the anaesthetic site
@en
P2093
P2860
P1476
Anaesthetic potencies of prima ...... nsions of the anaesthetic site
@en
P2093
J K Alifimoff
K W Miller
L L Firestone
P2860
P356
10.1111/J.1476-5381.1989.TB11777.X
P407
P577
1989-01-01T00:00:00Z