Mapping General Anesthetic Sites in Heteromeric γ-Aminobutyric Acid Type A Receptors Reveals a Potential For Targeting Receptor Subtypes. - Wikidata - awgldk - TriplyDB

Mapping General Anesthetic Sites in Heteromeric γ-Aminobutyric Acid Type A Receptors Reveals a Potential For Targeting Receptor Subtypes.

Mapping General Anesthetic Sites in Heteromeric γ-Aminobutyric Acid Type A Receptors Reveals a Potential For Targeting Receptor Subtypes.

http://www.wikidata.org/entity/Q38831924

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Association of Polymorphisms in Pharmacogenetic Candidate Genes with Propofol Susceptibility.The protective effects of propofol against CoCl2-induced HT22 cell hypoxia injury via PP2A/CAMKIIα/nNOS pathway.Conditions that Stabilize Membrane Domains Also Antagonize n-Alcohol Anesthesia Functional sites for anesthetics in GABAA receptors.Tryptophan and Cysteine Mutations in M1 Helices of α1β3γ2L γ-Aminobutyric Acid Type A Receptors Indicate Distinct Intersubunit Sites for Four Intravenous Anesthetics and One Orphan Site.Alphaxalone Binds in Inner Transmembrane β+-α- Interfaces of α1β3γ2 γ-Aminobutyric Acid Type A Receptors.Comparison of αβδ and αβγ GABAA receptors: Allosteric modulation and identification of subunit arrangement by site-selective general anesthetics.High-level production and purification in a functional state of an extrasynaptic gamma-aminobutyric acid type A receptor containing α4β3δ subunits.Recent progress on the molecular pharmacology of propofol.GABAA receptor: Positive and negative allosteric modulators.

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P2860

Mapping General Anesthetic Sites in Heteromeric γ-Aminobutyric Acid Type A Receptors Reveals a Potential For Targeting Receptor Subtypes.

http://www.wikidata.org/entity/Q38831924

description

2016 nî lūn-bûn

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Mapping General Anesthetic Sit ...... r Targeting Receptor Subtypes.

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Mapping General Anesthetic Sit ...... r Targeting Receptor Subtypes.

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Mapping General Anesthetic Sit ...... r Targeting Receptor Subtypes.

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Anesthesia & Analgesia

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Mapping General Anesthetic Sit ...... r Targeting Receptor Subtypes.

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Keith W Miller

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Stuart A Forman

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P2860

GABA A receptors: subtypes provide diversity of function and pharmacology

International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update

The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid

Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptors

Crystal structure of a human GABAA receptor

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

Principles of activation and permeation in an anion-selective Cys-loop receptor

Structure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine

Multisite Binding of a General Anesthetic to the Prokaryotic Pentameric Erwinia chrysanthemi Ligand-gated Ion Channel (ELIC)

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1263-1273

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