Direct involvement of breast tumor fibroblasts in the modulation of tamoxifen sensitivity
about
Breast Cancer-Associated Fibroblasts: Where We Are and Where We Need to GoA recapitulative three-dimensional model of breast carcinoma requires perfusion for multi-week growthTumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretionTamoxifen induces pleiotrophic changes in mammary stroma resulting in extracellular matrix that suppresses transformed phenotypesBreast tumour stroma is a prognostic indicator and target for therapy.Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivityCD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors.Responsiveness to PI3K and MEK inhibitors in breast cancer. Use of a 3D culture system to study pathways related to hormone independence in mice.Mesenchymal stem cells contribute to the chemoresistance of hepatocellular carcinoma cells in inflammatory environment by inducing autophagy.Primary cilia are decreased in breast cancer: analysis of a collection of human breast cancer cell lines and tissuesMalignant stroma increases luminal breast cancer cell proliferation and angiogenesis through platelet-derived growth factor signalingLow ERK phosphorylation in cancer-associated fibroblasts is associated with tamoxifen resistance in pre-menopausal breast cancer.Stromal expression of β-arrestin-1 predicts clinical outcome and tamoxifen response in breast cancer.Vascular endothelial growth factor reduces tamoxifen efficacy and promotes metastatic colonization and desmoplasia in breast tumorsCancer-associated fibroblasts induce high mobility group box 1 and contribute to resistance to doxorubicin in breast cancer cells.Stromal cells in tumor microenvironment and breast cancerExtensive rewiring of epithelial-stromal co-expression networks in breast cancerAnti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells.Physical Intimacy of Breast Cancer Cells with Mesenchymal Stem Cells Elicits Trastuzumab Resistance through Src ActivationHumanized anti-hepatocyte growth factor (HGF) antibody suppresses innate irinotecan (CPT-11) resistance induced by fibroblast-derived HGF.Stromal cells promote anti-estrogen resistance of breast cancer cells through an insulin-like growth factor binding protein 5 (IGFBP5)/B-cell leukemia/lymphoma 3 (Bcl-3) axisTamoxifen Action in ER-Negative Breast Cancer.Hierarchical paracrine interaction of breast cancer associated fibroblasts with cancer cells via hMAPK-microRNAs to drive ER-negative breast cancer phenotype.The tumor microenvironment modulates tamoxifen resistance in breast cancer: a role for soluble stromal factors and fibronectin through β1 integrin.Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer.Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin.High expression of stromal PDGFRβ is associated with reduced benefit of tamoxifen in breast cancerProteomic profiling of the tumor microenvironment: recent insights and the search for biomarkers.DNA methylome profiling beyond promoters - taking an epigenetic snapshot of the breast tumor microenvironment.Breast cancer complexity: implications of intratumoral heterogeneity in clinical management.Creating chemotherapeutic-resistant breast cancer cell lines: advances and future perspectives.Cancer-associated fibroblasts induce trastuzumab resistance in HER2 positive breast cancer cells.Breast tumor stroma: A driving force in the development of resistance to therapies.Letrozole-induced functional changes in carcinoma-associated fibroblasts and their influence on breast cancer cell biology.Advanced cell culture techniques for cancer drug discovery.Modeling colon adenocarcinomas in vitro a 3D co-culture system induces cancer-relevant pathways upon tumor cell and stromal fibroblast interaction.Fusion between cancer cells and myofibroblasts is involved in osteosarcoma.Primary breast tumor-derived cellular models: characterization of tumorigenic, metastatic, and cancer-associated fibroblasts in dissociated tumor (DT) cultures.Glioma cells escaped from cytotoxicity of temozolomide and vincristine by communicating with human astrocytes.TP53-inducible Glycolysis and Apoptosis Regulator (TIGAR) Metabolically Reprograms Carcinoma and Stromal Cells in Breast Cancer.
P2860
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P2860
Direct involvement of breast tumor fibroblasts in the modulation of tamoxifen sensitivity
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Direct involvement of breast tumor fibroblasts in the modulation of tamoxifen sensitivity
@ast
Direct involvement of breast tumor fibroblasts in the modulation of tamoxifen sensitivity
@en
type
label
Direct involvement of breast tumor fibroblasts in the modulation of tamoxifen sensitivity
@ast
Direct involvement of breast tumor fibroblasts in the modulation of tamoxifen sensitivity
@en
prefLabel
Direct involvement of breast tumor fibroblasts in the modulation of tamoxifen sensitivity
@ast
Direct involvement of breast tumor fibroblasts in the modulation of tamoxifen sensitivity
@en
P2093
P2860
P1476
Direct involvement of breast tumor fibroblasts in the modulation of tamoxifen sensitivity
@en
P2093
Kathryn A Carolin
Larry Tait
Malathy P V Shekhar
Steven Santner
P2860
P304
P356
10.2353/AJPATH.2007.061004
P407
P577
2007-05-01T00:00:00Z