The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans
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Pathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional crosstalk, and signaling addictionStructure of an Fab–Protease Complex Reveals a Highly Specific Non-canonical Mechanism of InhibitionIdentification of five serum protein markers for detection of ovarian cancer by antibody arraysHepatocyte growth factor-like protein is a positive regulator of early mammary gland ductal morphogenesisPredicting cancer involvement of genes from heterogeneous data.Apoptotic regulation of epithelial cellular extrusionPositional scanning synthetic combinatorial libraries for substrate profiling.Genetic and epigenetic somatic alterations in head and neck squamous cell carcinomas are globally coordinated but not locally targeted.The Ron receptor tyrosine kinase positively regulates angiogenic chemokine production in prostate cancer cellsStimulation of angiogenesis resulting from cooperation between macrophages and MDA-MB-231 breast cancer cells: proposed molecular mechanism and effect of tetrathiomolybdate.Tumor detection by imaging proteolytic activityRegulation of macrophage arginase expression and tumor growth by the Ron receptor tyrosine kinaseThe Ron receptor tyrosine kinase activates c-Abl to promote cell proliferation through tyrosine phosphorylation of PCNA in breast cancerA personalized committee classification approach to improving prediction of breast cancer metastasis.Met-related receptor tyrosine kinase Ron in tumor growth and metastasis.Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo.Ron receptor tyrosine kinase activation confers resistance to tamoxifen in breast cancer cell linesMost random gene expression signatures are significantly associated with breast cancer outcome.Diversity of matriptase expression level and function in breast cancer.Deletion or insertion in the first immunoglobulin-plexin-transcription (IPT) domain differentially regulates expression and tumorigenic activities of RON receptor Tyrosine Kinase.RON is not a prognostic marker for resectable pancreatic cancer.Phosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers.Matriptase and MET are prominently expressed at the site of bone metastasis in renal cell carcinoma: immunohistochemical analysis.Lessons in signaling and tumorigenesis from polyomavirus middle T antigen.Virtual screening and pharmacophore design for a novel theoretical inhibitor of macrophage stimulating factor as a metastatic agent.β-Catenin is required for Ron receptor-induced mammary tumorigenesisThe monoclonal antibody Zt/f2 targeting RON receptor tyrosine kinase as potential therapeutics against tumor growth-mediated by colon cancer cells.RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma.The epidermal growth factor receptor (EGFR) is proteolytically modified by the Matriptase-Prostasin serine protease cascade in cultured epithelial cells.Short-Form Ron Promotes Spontaneous Breast Cancer Metastasis through Interaction with Phosphoinositide 3-Kinase.Conditional deletion of β-catenin in mammary epithelial cells of Ron receptor, Mst1r, overexpressing mice alters mammary tumorigenesis.Vitamin D3-dependent VDR signaling delays ron-mediated breast tumorigenesis through suppression of β-catenin activity.HGFL supports mammary tumorigenesis by enhancing tumor cell intrinsic survival and influencing macrophage and T-cell responses.Preclinical Efficacy of Ron Kinase Inhibitors Alone and in Combination with PI3K Inhibitors for Treatment of sfRon-Expressing Breast Cancer Patient-Derived Xenografts.Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell CapacityTumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages.Ron tyrosine kinase receptor synergises with EGFR to confer adverse features in head and neck squamous cell carcinoma.The RON receptor tyrosine kinase promotes MSP-independent cell spreading and survival in breast epithelial cells.Clinical prognostic value of DNA methylation in hepatoblastoma: Four novel tumor suppressor candidates.Macrophages, more than just scavengers: their role in breast development and cancer.
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P2860
The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The macrophage-stimulating pro ...... dicts poor prognosis in humans
@ast
The macrophage-stimulating pro ...... dicts poor prognosis in humans
@en
type
label
The macrophage-stimulating pro ...... dicts poor prognosis in humans
@ast
The macrophage-stimulating pro ...... dicts poor prognosis in humans
@en
prefLabel
The macrophage-stimulating pro ...... dicts poor prognosis in humans
@ast
The macrophage-stimulating pro ...... dicts poor prognosis in humans
@en
P2093
P2860
P356
P1476
The macrophage-stimulating pro ...... dicts poor prognosis in humans
@en
P2093
Alana L Welm
Bruce H Hasegawa
Carmen Taylor
Dimitry S A Nuyten
J Michael Bishop
Julie B Sneddon
P2860
P304
P356
10.1073/PNAS.0702095104
P407
P577
2007-04-24T00:00:00Z