Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene - Wikidata - awgldk - TriplyDB

Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene

Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene

http://www.wikidata.org/entity/Q35760833

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ICP0 prevents RNase L-independent rRNA cleavage in herpes simplex virus type 1-infected cells Identification of interferon-stimulated gene 15 as an antiviral molecule during Sindbis virus infection in vivo.Antiviral actions of interferons Alpha interferon induces distinct translational control programs to suppress hepatitis C virus RNA replication Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action Complete sequence and comparative analysis of the genome of herpes B virus (Cercopithecine herpesvirus 1) from a rhesus monkey Herpes simplex virus-infected cell protein 0 blocks the silencing of viral DNA by dissociating histone deacetylases from the CoREST-REST complex Viral encounters with 2',5'-oligoadenylate synthetase and RNase L during the interferon antiviral response Inhibition of Transcription and Translation in Sindbis Virus-Infected Cells Interferon-inducible antiviral effectors The role of RNAi and microRNAs in animal virus replication and antiviral immunity An Evolutionary View of the Arms Race between Protein Kinase R and Large DNA Viruses The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses The virome in mammalian physiology and disease Proteinase 2Apro Is Essential for Enterovirus Replication in Type I Interferon-Treated Cells Autophagy in health and disease: a double-edged sword Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory Neurons Evasion of cellular antiviral responses by human cytomegalovirus TRS1 and IRS1 Altered expression of antiviral cytokine mRNAs associated with cyclophosphamide's enhancement of viral oncolysis Herpes simplex type I (HSV-1) infection of the nervous system: is an immune response a good thing?West Nile virus inhibits the signal transduction pathway of alpha interferon.Distinctive roles for 2',5'-oligoadenylate synthetases and double-stranded RNA-dependent protein kinase R in the in vivo antiviral effect of an adenoviral vector expressing murine IFN-beta.Interferon-beta suppresses herpes simplex virus type 1 replication in trigeminal ganglion cells through an RNase L-dependent pathway AlaArg motif in the carboxyl terminus of the gamma(1)34.5 protein of herpes simplex virus type 1 is required for the formation of a high-molecular-weight complex that dephosphorylates eIF-2alpha.A herpes simplex virus type 1 gamma34.5 second-site suppressor mutant that exhibits enhanced growth in cultured glioblastoma cells is severely attenuated in animals A mutation in the latency-related gene of bovine herpesvirus 1 leads to impaired ocular shedding in acutely infected calves.Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway Recent progress in herpes simplex virus immunobiology and vaccine research Low TRBP levels support an innate human immunodeficiency virus type 1 resistance in astrocytes by enhancing the PKR antiviral response.Intrinsic innate immunity fails to control herpes simplex virus and vesicular stomatitis virus replication in sensory neurons and fibroblasts.Up to four distinct polypeptides are produced from the γ34.5 open reading frame of herpes simplex virus 2 Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1 Second-site mutation outside of the U(S)10-12 domain of Deltagamma(1)34.5 herpes simplex virus 1 recombinant blocks the shutoff of protein synthesis induced by activated protein kinase R and partially restores neurovirulence.Complementation of vaccinia virus lacking the double-stranded RNA-binding protein gene E3L by human cytomegalovirus A mutation in the latency-related gene of bovine herpesvirus 1 disrupts the latency reactivation cycle in calves.The antiviral efficacy of the murine alpha-1 interferon transgene against ocular herpes simplex virus type 1 requires the presence of CD4(+), alpha/beta T-cell receptor-positive T lymphocytes with the capacity to produce gamma interferon Signals that dictate nuclear, nucleolar, and cytoplasmic shuttling of the gamma(1)34.5 protein of herpes simplex virus type 1 Alpha/Beta interferon and gamma interferon synergize to inhibit the replication of herpes simplex virus type 1.Noninvasive bioluminescence imaging of herpes simplex virus type 1 infection and therapy in living mice.

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P2860

Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene

http://www.wikidata.org/entity/Q35760833

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2000 nî lūn-bûn

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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2000年论文

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2000年论文

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name

Specific phenotypic restoratio ...... kout of a host resistance gene

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Specific phenotypic restoratio ...... kout of a host resistance gene

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Specific phenotypic restoratio ...... kout of a host resistance gene

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Specific phenotypic restoratio ...... kout of a host resistance gene

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Specific phenotypic restoratio ...... kout of a host resistance gene

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Specific phenotypic restoratio ...... kout of a host resistance gene

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Specific phenotypic restoratio ...... kout of a host resistance gene

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P2093

B R Williams

http://www.w3.org/2001/XMLSchema#string

D A Leib

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H W Virgin

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M A Machalek

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R H Silverman

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P2860

Functional role of type I and type II interferons in antiviral defense

How cells respond to interferons

Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

Association of a M(r) 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor eIF-2 alpha and premature shutoff of protein synthesis after infection with gamma 134.5- mutants of her

Replication of herpes simplex virus type 1 within trigeminal ganglia is required for high frequency but not high viral genome copy number latency.

Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB

Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L

Sphingolipid functions in Saccharomyces cerevisiae: comparison to mammals.

Herpes simplex virus 1 gamma(1)34.5 gene function, which blocks the host response to infection, maps in the homologous domain of the genes expressed during growth arrest and DNA damage.

Replication, establishment of latency, and induced reactivation of herpes simplex virus gamma 1 34.5 deletion mutants in rodent models.

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6097-6101

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scholarly article

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10.1073/PNAS.100415697

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11

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97

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2000-05-01T00:00:00Z

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12515512

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10801979

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P932

18564

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