Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.
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Calmodulin protects Aurora B on the midbody to regulate the fidelity of cytokinesis.Kif2a depletion generates chromosome segregation and pole coalescence defects in animal caps and inhibits gastrulation of the Xenopus embryo.Evidence of colorectal cancer-associated mutation in MCAK: a computational report.Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells.Ras transformation uncouples the kinesin-coordinated cellular nutrient responseIntegrity of p53 associated pathways determines induction of apoptosis of tumor cells resistant to Aurora-A kinase inhibitorsNew Insights into the Coupling between Microtubule Depolymerization and ATP Hydrolysis by Kinesin-13 Protein Kif2C.Signaling-dependent phosphorylation of mitotic centromere-associated kinesin regulates microtubule depolymerization and its centrosomal localizationFBXW7 is involved in Aurora B degradation.NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity.Intracellular targets for a phosphotyrosine peptidomimetic include the mitotic kinesin, MCAKBeyond taxol: microtubule-based treatment of disease and injury of the nervous system.GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK.Kif2a regulates spindle organization and cell cycle progression in meiotic oocytes.Oncogenic role of kinesin proteins and targeting kinesin therapy.Battle of the eternal rivals: restoring functional p53 and inhibiting Polo-like kinase 1 as cancer therapy.Functional analysis of phosphorylation of the mitotic centromere-associated kinesin by Aurora B kinase in human tumor cellsMicrotubule-based force generation.Polo-like kinase 1 regulates the stability of the mitotic centromere-associated kinesin in mitosis.EGFR/MEK/ERK/CDK5-dependent integrin-independent FAK phosphorylated on serine 732 contributes to microtubule depolymerization and mitosis in tumor cells.RNA-binding protein RBM8A (Y14) and MAGOH localize to centrosome in human A549 cells.Peloruside A is a microtubule-stabilizing agent with exceptional anti-migratory properties in human endothelial cellsThe activity regulation of the mitotic centromere-associated kinesin by Polo-like kinase 1Regulating PLK1 dynamics by Cullin3/KLHL22-mediated ubiquitylation.Tumor suppressor protein p53-mediated repression of human mitotic centromere-associated kinesin gene expression is exerted via down-regulation of Sp1 level.Bioinformatics analysis of SRSF1-controlled gene networks in colorectal cancer.Targeting SxIP-EB1 interaction: An integrated approach to the discovery of small molecule modulators of dynamic binding sites.Kinesin superfamily: roles in breast cancer, patient prognosis and therapeutics.Network integration of multi-tumour omics data suggests novel targeting strategies
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P2860
Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.
@ast
Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.
@en
type
label
Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.
@ast
Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.
@en
prefLabel
Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.
@ast
Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.
@en
P2093
P2860
P921
P356
P1433
P1476
Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target
@en
P2093
Frank Louwen
Juping Yuan
Mourad Sanhaji
P2860
P304
P356
10.18632/ONCOTARGET.416
P407
P5008
P577
2011-12-01T00:00:00Z