Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.
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The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementiaGenetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation updateLRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stressThe H50Q mutation enhances α-synuclein aggregation, secretion, and toxicityRedistribution of DAT/α-synuclein complexes visualized by "in situ" proximity ligation assay in transgenic mice modelling early Parkinson's diseaseAlpha-synuclein and polyunsaturated fatty acids promote clathrin-mediated endocytosis and synaptic vesicle recyclingResidual structure, backbone dynamics, and interactions within the synuclein familyNUB1 suppresses the formation of Lewy body-like inclusions by proteasomal degradation of synphilin-1Dorfin localizes to the ubiquitylated inclusions in Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, and amyotrophic lateral sclerosisPropagation of prions causing synucleinopathies in cultured cellsSystematic mutagenesis of α-synuclein reveals distinct sequence requirements for physiological and pathological activitiesDynamic structural flexibility of α-synucleinPhysicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)Glia and alpha-synuclein in neurodegeneration: A complex interactionThe benefits of humanized yeast models to study Parkinson's diseasePathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body diseaseC-Terminal Tyrosine Residue Modifications Modulate the Protective Phosphorylation of Serine 129 of α-Synuclein in a Yeast Model of Parkinson's Disease.More than a Rumor Spreads in Parkinson's DiseaseThe contribution of alpha synuclein to neuronal survival and function - Implications for Parkinson's diseaseSerotonin 1A Receptors on Astrocytes as a Potential Target for the Treatment of Parkinson's DiseaseDistinct α-synuclein strains differentially promote tau inclusions in neuronsThe aetiology of idiopathic Parkinson's diseaseEnvironmental exposures and gene regulation in disease etiologyDisease-toxicant interactions in Parkinson's disease neuropathologyNeurotoxicity of the Parkinson Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish EmbryosPathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic miceClustering of alpha-synuclein on supported lipid bilayers: role of anionic lipid, protein, and divalent ion concentrationThe Solution Structure and Dynamics of Full-length Human Cerebral Dopamine Neurotrophic Factor and Its Neuroprotective Role against α-Synuclein Oligomers.Clearance and phosphorylation of alpha-synuclein are inhibited in methionine sulfoxide reductase a null yeast cells.Widespread alterations of alpha-synuclein in multiple system atrophyα-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies.Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice.At low concentrations, 3,4-dihydroxyphenylacetic acid (DOPAC) binds non-covalently to alpha-synuclein and prevents its fibrillationEvaluation of alpha-synuclein immunohistochemical methods used by invited expertsProfile of cognitive impairment in Parkinson's diseaseNovel antibody capture assay for paraffin-embedded tissue detects wide-ranging amyloid beta and paired helical filament-tau accumulation in cognitively normal older adults.A Novel Microfluidic Cell Co-culture Platform for the Study of the Molecular Mechanisms of Parkinson's Disease and Other SynucleinopathiesCo-expression of truncated and full-length tau induces severe neurotoxicityIsolation of a human single chain antibody fragment against oligomeric alpha-synuclein that inhibits aggregation and prevents alpha-synuclein-induced toxicityCathepsin D is the main lysosomal enzyme involved in the degradation of alpha-synuclein and generation of its carboxy-terminally truncated species.
P2860
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P2860
Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Aggregation of alpha-synuclein ...... and dementia with Lewy bodies.
@ast
Aggregation of alpha-synuclein ...... and dementia with Lewy bodies.
@en
type
label
Aggregation of alpha-synuclein ...... and dementia with Lewy bodies.
@ast
Aggregation of alpha-synuclein ...... and dementia with Lewy bodies.
@en
prefLabel
Aggregation of alpha-synuclein ...... and dementia with Lewy bodies.
@ast
Aggregation of alpha-synuclein ...... and dementia with Lewy bodies.
@en
P2093
P2860
P921
P1476
Aggregation of alpha-synuclein ...... and dementia with Lewy bodies
@en
P2093
Iwatsubo T
Trojanowski JQ
P2860
P304
P407
P577
1998-04-01T00:00:00Z