Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia.
about
Turning receptors on and off with intracellular pepducins: new insights into G-protein-coupled receptor drug developmentThe tumor microenvironment shapes hallmarks of mature B-cell malignancies.Allosteric Activation of a G Protein-coupled Receptor with Cell-penetrating Receptor MimeticsInhibition of CXCR4 by LY2624587, a Fully Humanized Anti-CXCR4 Antibody Induces Apoptosis of Hematologic MalignanciesA rare fraction of drug-resistant follicular lymphoma cancer stem cells interacts with follicular dendritic cells to maintain tumourigenic potentialStromal cell contribution to human follicular lymphoma pathogenesis.Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein.Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphomaDynamic Interactions Between Cancer Stem Cells And Their Stromal Partners.Homeostatic chemokines guide lymphoma cells to tumor growth-promoting niches within secondary lymphoid organs.Cell penetration: scope and limitations by the application of cell-penetrating peptides.Intracellular delivery of nanocarriers and targeting to subcellular organelles.CXCR4 expression enhances diffuse large B cell lymphoma dissemination and decreases patient survival.Regulation of the Melanocortin-Sensitive Adenylate Cyclase System by N-Acylated Peptide 71-82 of Type 4 Melanocortin Receptor.Pepducins and Other Lipidated Peptides as Mechanistic Probes and Therapeutics.Reversal of murine alcoholic steatohepatitis by pepducin-based functional blockade of interleukin-8 receptorsGlobal gene expression changes of in vitro stimulated human transformed germinal centre B cells as surrogate for oncogenic pathway activation in individual aggressive B cell lymphomasThe CXCR4 antagonist plerixafor enhances the effect of rituximab in diffuse large B-cell lymphoma cell lines.Cancer stem cell and stromal microenvironmentThe role of G protein-coupled receptors in lymphoid malignancies.Junctional Adhesion Molecule-A Is Highly Expressed on Human Hematopoietic Repopulating Cells and Associates with the Key Hematopoietic Chemokine Receptor CXCR4.Phase I dose-escalation study of F50067, a humanized anti-CXCR4 monoclonal antibody alone and in combination with lenalidomide and low-dose dexamethasone, in relapsed or refractory multiple myeloma.Comparison of interleukin-2-inducible kinase (ITK) inhibitors and potential for combination therapies for T-cell lymphoma
P2860
Q27024397-2732B877-0941-4908-9895-86225C6D5EE1Q27687567-AC066647-D721-4A4E-AA6F-AE5D070B301DQ35860717-5D83D404-1C9B-4646-B97F-9C1E0B22BB51Q35949372-E40183A7-DF52-42E4-945F-AC20CCA84E72Q36028412-263B2185-F9E6-440A-8B64-7EFD7C031F3DQ36208267-78E48262-9624-4995-8813-590FDD0429A2Q37421226-72CEAC2D-33B4-4083-AB8E-0FDFCEC1A1B5Q37427684-EB005670-2CEE-429C-8A26-B305835FCDDCQ37641700-1AA0A9E0-51D9-4F39-A68A-A8CDE7395819Q38009278-7AF9C364-0DCC-4AB6-AC58-B7D41EA288C7Q38238902-174C4C67-281F-4180-8324-8BB2176A0217Q38584491-E5EE35B2-A040-43C8-BE97-99CCC65888A6Q38955569-AB444358-A187-4C06-AADB-D9DF9CA0029CQ40290455-97B317E6-D261-47B0-AAD4-3675F975A7ACQ40405065-70888BA7-C3DF-4E81-9805-E300F41F6F56Q41151392-81CC92F8-7C43-4ACF-9735-BB94A21FAD94Q42005623-0F626037-E90A-41BA-A605-65C69DBF9944Q42006192-0A737FAB-4057-40F0-B852-9B33C97A14DAQ42540118-B73E7506-0413-4A99-9A76-81357A9132BDQ47960121-E0163004-391B-4E6C-B13D-2C2EF829AB3FQ52885254-4C9B8E3A-800E-4186-AFA5-C5DF9E028FDFQ55059834-146225FC-4D82-4048-B239-2740D1307DBEQ58705889-586A7431-27BB-4F92-92DF-08E82F5E92F6
P2860
Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia.
@ast
Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia.
@en
type
label
Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia.
@ast
Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia.
@en
prefLabel
Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia.
@ast
Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia.
@en
P2093
P2860
P1433
P1476
Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia.
@en
P2093
Andreas K Klein
Athan Kuliopulos
Katie O'Callaghan
Kellie Sprague
Lidija Covic
Mo-Ying Hsieh
Nga Nguyen
Nicole C Kaneider
Richard A Van Etten
P2860
P304
P356
10.1182/BLOOD-2011-04-347518
P407
P577
2011-12-20T00:00:00Z