A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
about
GPCR oligomers in pharmacology and signalingMolecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) couplingActivation and allosteric modulation of a muscarinic acetylcholine receptorAdenosine A(2A) receptors assemble into higher-order oligomers at the plasma membraneDopamine D2 receptors form higher order oligomers at physiological expression levelsEmerging roles for the FSH receptor adapter protein APPL1 and overlap of a putative 14-3-3τ interaction domain with a canonical G-protein interaction siteIdentification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A·mGlu2) receptor heteromerization and its psychoactive behavioral functionStructural model of ligand-G protein-coupled receptor (GPCR) complex based on experimental double mutant cycle data: MT7 snake toxin bound to dimeric hM1 muscarinic receptorStructure of a nanobody-stabilized active state of the β(2) adrenoceptorStructure and function of an irreversible agonist-β(2) adrenoceptor complexDistinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein couplingAllostery at G protein-coupled receptor homo- and heteromers: uncharted pharmacological landscapesCrystal structure of the β2 adrenergic receptor-Gs protein complexConstitutive dimerization of the G-protein coupled receptor, neurotensin receptor 1, reconstituted into phospholipid bilayersBuilding a new conceptual framework for receptor heteromersCell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerizationHigh-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptorBasic Pharmacological and Structural Evidence for Class A G-Protein-Coupled Receptor HeteromerizationOpportunities for functional selectivity in GPCR antibodiesQuaternary structure of a G-protein-coupled receptor heterotetramer in complex with Gi and Gs.Communication over the network of binary switches regulates the activation of A2A adenosine receptorDimeric Arrangement of the Parathyroid Hormone Receptor and a Structural Mechanism for Ligand-induced DissociationN-Terminal T4 Lysozyme Fusion Facilitates Crystallization of a G Protein Coupled ReceptorAdrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobodyEvidence for Follicle-stimulating Hormone Receptor as a Functional TrimerCovalent agonists for studying G protein-coupled receptor activationNanobody stabilization of G protein-coupled receptor conformational states.Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding PairMembrane-Mediated Oligomerization of G Protein Coupled Receptors and Its Implications for GPCR FunctionA new mechanism of allostery in a G protein-coupled receptor dimerOligomer size of the serotonin 5-hydroxytryptamine 2C (5-HT2C) receptor revealed by fluorescence correlation spectroscopy with photon counting histogram analysis: evidence for homodimers without monomers or tetramersIsolation, characterization, and stability of discretely-sized nanolipoprotein particles assembled with apolipophorin-IIICharacterization of de novo synthesized GPCRs supported in nanolipoprotein discsConformational antibody binding to a native, cell-free expressed GPCR in block copolymer membranesFunctional Stability of the Human Kappa Opioid Receptor Reconstituted in Nanodiscs Revealed by a Time-Resolved Scintillation Proximity AssayThe oligomeric state sets GABA(B) receptor signalling efficacyModulation of the interaction between neurotensin receptor NTS1 and Gq protein by lipidAdenosine receptors as drug targets--what are the challenges?Binding of amyloid beta peptide to beta2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivityActivation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes.
P2860
Q21198901-4631CFEA-699C-4A5C-B327-B75CE210E80AQ24300492-E04A79B3-E59E-4A9C-9EF2-C09054FE2723Q24308061-6F434185-450D-4B34-8C6F-FBCE6C181984Q24315105-27D434F8-BC27-4D4E-9A97-1954BCC99249Q24318766-3BC16C1C-CD7A-4C6C-B5A8-D1796AD91BD8Q24337429-4B3326A9-6619-4C54-B0DA-368D5EEBEF3AQ24594672-BB973327-B4EA-4E54-B849-A0BBBB95EA48Q24595276-1F6A6163-5FDF-4446-92B5-1692B990A109Q24597139-D41A03DB-AFD9-4C1C-B386-260434B3AD32Q24620291-F65EC698-11D9-42E8-98D2-C0BB4E7195F2Q24624255-D168F63B-1AD4-4962-AEC8-51B15582D067Q24633877-936E9863-D73F-46F1-887C-1F918065CD70Q24635327-A8FCF452-E66E-4D02-9379-B6D8E7A7E4B3Q24644172-96E66C49-F063-411B-B2BF-9700C592CF7DQ24644975-00D7D16C-F487-4525-8C2E-CDB78E595E53Q24653438-74B010C6-A7BC-44AA-9C3E-6BA29E1C71B3Q24657484-4F24E0D2-5F7D-4B62-9CC1-5607EF9EC851Q26749791-C5D3CE1B-2901-4C85-9E0B-DC0FC202E93BQ26859602-B58ABA79-9EC0-49EE-AB91-9D56D8069D77Q27305013-1804F9D6-F5E6-458F-8F25-AAB0523D6247Q27320028-BB684973-F048-46C9-9461-22022B365ABEQ27659967-EA00555C-84A5-4961-BE99-2EE5C4F8CAD6Q27674422-301C4090-E202-466E-AC4B-332C730F637DQ27680016-7F821CE9-8B28-4E74-A6CC-21D888E76736Q27682749-71834C04-8199-4415-9553-43FD6EC2C764Q27684620-53873571-DDAD-4EF7-BBAC-27F3743B50DEQ27690729-D8D25409-A61C-42F8-9F10-6713A2A963B3Q27702255-FC42172C-BFA8-4EEB-94FC-43BC31B1835AQ28072820-3CABF4D2-2B9B-4286-B0CA-BEA7E544C5EEQ28245604-0C401B32-F265-4B90-95A8-3EF79D674380Q28266794-1AADEB84-BC0D-4E25-A2A8-C39195D757EEQ28474859-CCB5A4B9-BF8C-478D-9F16-02F26BE3A7C8Q28484130-637083C0-C9F5-43E1-A8C9-882986622485Q28543955-9646A472-290A-4223-9EA8-849BB4AA416FQ28551129-A97170C5-891F-47DD-9C6F-138672EC2F01Q28570219-0D908648-944B-46D3-ACCC-4ADAD0393EDBQ28584277-8D11A472-9D21-4C4F-9C0C-EB0D067A9C33Q29346491-5BB327D8-161F-49C3-9DBC-32CAEC214F23Q30175692-B7C8C185-612B-4CCA-ACA3-95EA15CBB414Q30364526-BA273E2E-C8F1-4D16-A861-52DAF7A4736A
P2860
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A monomeric G protein-coupled ...... iently activates its G protein
@ast
A monomeric G protein-coupled ...... iently activates its G protein
@en
type
label
A monomeric G protein-coupled ...... iently activates its G protein
@ast
A monomeric G protein-coupled ...... iently activates its G protein
@en
prefLabel
A monomeric G protein-coupled ...... iently activates its G protein
@ast
A monomeric G protein-coupled ...... iently activates its G protein
@en
P2093
P2860
P356
P1476
A monomeric G protein-coupled ...... iently activates its G protein
@en
P2093
Matthew R Whorton
Richard N Zare
Roger K Sunahara
Søren G F Rasmussen
P2860
P304
P356
10.1073/PNAS.0611448104
P407
P577
2007-04-23T00:00:00Z