Amsacrine as a topoisomerase II poison: importance of drug-DNA interactions.
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On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugsSynthesis, DNA Binding, and Antiproliferative Activity of Novel Acridine-Thiosemicarbazone DerivativesA synthetic lethal approach for compound and target identification in Staphylococcus aureusIdentification of compounds that modulate retinol signaling using a cell-based qHTS assay.New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway.Epimerization of green tea catechins during brewing does not affect the ability to poison human type II topoisomerases.A "Double-Edged" Scaffold: Antitumor Power within the Antibacterial Quinolone.Cestrum nocturnum Flower Extracts Attenuate Proliferation and Induce Apoptosis in Malignant Cells through Inducing DNA Damage and Inhibiting Topoisomerase II Activity.Acridine and its derivatives: a patent review (2009 - 2013).New thiazacridine agents: Synthesis, physical and chemical characterization, and in vitro anticancer evaluation.An overview of quinoline as a privileged scaffold in cancer drug discovery.Amsacrine-induced apoptosis of human leukemia U937 cells is mediated by the inhibition of AKT- and ERK-induced stabilization of MCL1.Chemical Genetic Screen Identifies Natural Products that Modulate Centriole Number.Novel trifluoromethylated 9-amino-3,4-dihydroacridin-1(2H)-ones act as covalent poisons of human topoisomerase IIα.Pericyclic rearrangements of N-heterocyclic carbenes of indazole to substituted 9-aminoacridines.Imidazoles as potential anticancer agents
P2860
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P2860
Amsacrine as a topoisomerase II poison: importance of drug-DNA interactions.
description
2012 nî lūn-bûn
@nan
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
@zh-cn
name
Amsacrine as a topoisomerase II poison: importance of drug-DNA interactions.
@ast
Amsacrine as a topoisomerase II poison: importance of drug-DNA interactions.
@en
type
label
Amsacrine as a topoisomerase II poison: importance of drug-DNA interactions.
@ast
Amsacrine as a topoisomerase II poison: importance of drug-DNA interactions.
@en
prefLabel
Amsacrine as a topoisomerase II poison: importance of drug-DNA interactions.
@ast
Amsacrine as a topoisomerase II poison: importance of drug-DNA interactions.
@en
P2093
P2860
P356
P1433
P1476
Amsacrine as a topoisomerase II poison: importance of drug-DNA interactions.
@en
P2093
Adam C Ketron
David E Graves
Neil Osheroff
William A Denny
P2860
P304
P356
10.1021/BI201159B
P407
P577
2012-02-10T00:00:00Z