Detection of genomic amplification of the human telomerase gene (TERC) in cytologic specimens as a genetic test for the diagnosis of cervical dysplasia
about
Genomic amplification of the human telomerase gene (TERC) in pap smears predicts the development of cervical cancerThe consequences of chromosomal aneuploidy on the transcriptome of cancer cellsIncreased gene copy numbers at chromosome 20q are frequent in both squamous cell carcinomas and adenocarcinomas of the cervix3q26 amplification is an effective negative triage test for LSIL: a historical prospective studyHigh-resolution genomic profiling of human papillomavirus-associated vulval neoplasia.Gene amplification of EGFR and its clinical significance in various cervical (lesions) lesions using cytology and FISHIncrease in viral load, viral integration, and gain of telomerase genes during uterine cervical carcinogenesis can be simultaneously assessed by the HPV 16/18 MLPA-assay.Detection of TERC amplification in cervical epithelial cells for the diagnosis of high-grade cervical lesions and invasive cancer: a multicenter study in China.A comprehensive continuous-time model for the appearance of CGH signal due to chromosomal missegregations during mitosis.Expression of the p53 target Wig-1 is associated with HPV status and patient survival in cervical carcinomaIntegrated genomic and transcriptional profiling identifies chromosomal loci with altered gene expression in cervical cancerThe significant diagnostic value of human telomerase RNA component (hTERC) gene detection in high-grade cervical lesions and invasive cancer.c-myc copy number gain is a powerful prognosticator of disease outcome in cervical dysplasiaCircadian regulation of molecular, dietary, and metabolic signaling mechanisms of human breast cancer growth by the nocturnal melatonin signal and the consequences of its disruption by light at night.Advanced molecular cytogenetics in human and mouseGenomic amplification patterns of human telomerase RNA gene and C-MYC in liquid-based cytological specimens used for the detection of high-grade cervical intraepithelial neoplasiaChromosomal biomarkers for detection of human papillomavirus associated genomic instability in epithelial cells of cervical cytology specimensMET and PTEN gene copy numbers and Ki-67 protein expression associate with pathologic complete response in ERBB2-positive breast carcinoma patients treated with neoadjuvant trastuzumab-based therapy.Single-cell genetic analysis of ductal carcinoma in situ and invasive breast cancer reveals enormous tumor heterogeneity yet conserved genomic imbalances and gain of MYC during progression.The detection of hTERC amplification using fluorescence in situ hybridization in the diagnosis and prognosis of cervical intraepithelial neoplasia: a case control study.Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer.Molecular cytogenetics of mouse models of breast cancerSignificance of micronucleus in cervical intraepithelial lesions and carcinoma.Frequent gain of the human telomerase gene TERC at 3q26 in cervical adenocarcinomas.The use of genetic markers to identify lung cancer in fine needle aspiration samples.Detention of HPV L1 Capsid Protein and hTERC Gene in Screening of Cervical CancerIncreased copy number of the TERT and TERC telomerase subunit genes in cancer cells.Chromosomal gains measured in cytology samples from women with abnormal cervical cancer screening results.Detection of genomic amplification of the human telomerase gene TERC, a potential marker for triage of women with HPV-positive, abnormal Pap smears.Fluorescence in situ hybridization markers for prediction of cervical lymph node metastases.The current position and the future perspectives of cervical cancer screening.FHACT: the FISH-based HPV-associated cancer test that detects nonrandom gain at four genomic loci as biomarkers of disease progression.Telomerase and the process of cervical carcinogenesis.Determination of malignant potential of cervical intraepithelial neoplasia.Management of high-risk HPV-positive women for detection of cervical (pre)cancer.Gene dosage alterations revealed by cDNA microarray analysis in cervical cancer: identification of candidate amplified and overexpressed genes.Multiple forms of genetic instability within a 2-Mb chromosomal segment of 3q26.3-q27 are associated with development of esophageal adenocarcinoma.Amplification of specific chromosomal regions assessed by fluorescent in situ hybridization on Pap smears to be added as screening tool for identifying women at risk of progressing to cervical cancer.Comparative study of the cervista and hybrid capture 2 methods in detecting high-risk human papillomavirus in cervical lesions.Genomic integration of oncogenic HPV and gain of the human telomerase gene TERC at 3q26 are strongly associated events in the progression of uterine cervical dysplasia to invasive cancer.
P2860
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P2860
Detection of genomic amplification of the human telomerase gene (TERC) in cytologic specimens as a genetic test for the diagnosis of cervical dysplasia
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Detection of genomic amplifica ...... iagnosis of cervical dysplasia
@ast
Detection of genomic amplifica ...... iagnosis of cervical dysplasia
@en
type
label
Detection of genomic amplifica ...... iagnosis of cervical dysplasia
@ast
Detection of genomic amplifica ...... iagnosis of cervical dysplasia
@en
prefLabel
Detection of genomic amplifica ...... iagnosis of cervical dysplasia
@ast
Detection of genomic amplifica ...... iagnosis of cervical dysplasia
@en
P2093
P2860
P1476
Detection of genomic amplifica ...... iagnosis of cervical dysplasia
@en
P2093
Frances H Burroughs
Kerstin Heselmeyer-Haddad
Kim Wilber
Larry E Morrison
Mark E Sherman
Nadia Chaudhri
Nicole White
Philip E Castle
Thomas Ried
P2860
P304
P356
10.1016/S0002-9440(10)63498-0
P407
P577
2003-10-01T00:00:00Z