Role of Insulin in the Regulation of Proprotein Convertase Subtilisin/Kexin Type 9. - Wikidata - awgldk - TriplyDB

Role of Insulin in the Regulation of Proprotein Convertase Subtilisin/Kexin Type 9.

Role of Insulin in the Regulation of Proprotein Convertase Subtilisin/Kexin Type 9.

http://www.wikidata.org/entity/Q35794774

about

Physiological and therapeutic regulation of PCSK9 activity in cardiovascular disease.Design and rationale of the ODYSSEY DM-DYSLIPIDEMIA trial: lipid-lowering efficacy and safety of alirocumab in individuals with type 2 diabetes and mixed dyslipidaemia at high cardiovascular risk.PCSK9 inhibitors - from discovery of a single mutation to a groundbreaking therapy of lipid disorders in one decade.The enigmatic role of sortilin in lipoprotein metabolism.Effect of Leptin Replacement on PCSK9 in ob/ob Mice and Female Lipodystrophic Patients.Translational and Therapeutic Approaches to the Understanding and Treatment of Dyslipidemia Impact of Diabetes Mellitus.Lowering serum lipids via PCSK9-targeting drugs: current advances and future perspectives.PCSK9 targets important for lipid metabolism Calorically restricted diets decrease PCSK9 in overweight adolescents.Proprotein convertase subtilisin/kexin type 9 (PCSK9) and metabolic syndrome: insights on insulin resistance, inflammation, and atherogenic dyslipidemia.Obesity and type 2 diabetes are associated with elevated PCSK9 levels in young women.Targeting low-density lipoprotein cholesterol with PCSK9 inhibitors.Analysis of the association between plasma PCSK9 and Lp(a) in Han Chinese.PCSK9 signaling pathways and their potential importance in clinical practice.Plasma proprotein-convertase-subtilisin/kexin type 9 (PCSK9) and cardiovascular events in type 2 diabetes.PCSK9 Is Increased in Youth With Type 1 Diabetes.Circulating PCSK9 levels and 2-hPG are positively correlated in metabolic diseases in a Chinese Han population.Highlighting Diabetes Mellitus: The Epidemic Continues.Glycaemic control influences the relationship between plasma PCSK9 and LDL cholesterol in type 1 diabetes.Liraglutide downregulates hepatic LDL receptor and PCSK9 expression in HepG2 cells and db/db mice through a HNF-1a dependent mechanism.Hepatocellular carcinoma-associated hypercholesterolemia: involvement of proprotein-convertase-subtilisin-kexin type-9 (PCSK9)

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Role of Insulin in the Regulation of Proprotein Convertase Subtilisin/Kexin Type 9.

http://www.wikidata.org/entity/Q35794774

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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Role of Insulin in the Regulation of Proprotein Convertase Subtilisin/Kexin Type 9.

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Role of Insulin in the Regulation of Proprotein Convertase Subtilisin/Kexin Type 9.

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Role of Insulin in the Regulation of Proprotein Convertase Subtilisin/Kexin Type 9.

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Role of Insulin in the Regulation of Proprotein Convertase Subtilisin/Kexin Type 9.

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ATVBAHA.115.305688

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Arteriosclerosis, Thrombosis, and Vascular Biology

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Role of Insulin in the Regulation of Proprotein Convertase Subtilisin/Kexin Type 9

@en

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Alisha V Ling

http://www.w3.org/2001/XMLSchema#string

Dong-Ju Shin

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Ji Miao

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Jingwen Liu

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Mark J Graham

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Praveen V Manthena

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Rosanne M Crooke

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Sudha B Biddinger

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P2860

Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory element-binding protein 1c

The PCSK9 decade

LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor

Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

Importance of proprotein convertase subtilisin/kexin type 9 in the hormonal and dietary regulation of rat liver low-density lipoprotein receptors

Sequence variations in PCSK9, low LDL, and protection against coronary heart disease

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus.

Fasting reduces plasma proprotein convertase, subtilisin/kexin type 9 and cholesterol biosynthesis in humans.

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1589-1596

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scholarly article

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10.1161/ATVBAHA.115.305688

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7

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35

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2015-05-28T00:00:00Z

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26023080

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4484737

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