Discovery of an inhibitor of a transcription factor using small molecule microarrays and diversity-oriented synthesis.
about
Diversity-oriented synthetic strategies applied to cancer chemical biology and drug discoveryExpanding the number of 'druggable' targets: non-enzymes and protein-protein interactionsThe p53 pathway as a target in cancer therapeutics: obstacles and promiseOncogenomics and the development of new cancer therapiesDesign and synthesis of new bicyclic diketopiperazines as scaffolds for receptor probes of structurally diverse functionality.Protein "fingerprinting" in complex mixtures with peptoid microarrays.Diversity-oriented synthesis: exploring the intersections between chemistry and biology.Protein and small molecule microarrays: powerful tools for high-throughput proteomics.Targeted delivery of multifunctional magnetic nanoparticles.Small-molecule microarrays as tools in ligand discovery.Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries.Robust and systematic drug screening method using chemical arrays and the protein library: identification of novel inhibitors of carbonic anhydrase II.Combination chemical geneticsSmall molecule microarrays of RNA-focused peptoids help identify inhibitors of a pathogenic group I intronDiscovering ligands for a microRNA precursor with peptoid microarrays.Macromolecular scaffolds for immobilizing small molecule microarrays in label-free detection of protein-ligand interactions on solid support.Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic HedgehogSmall molecule microarrays enable the discovery of compounds that bind the Alzheimer's Aβ peptide and reduce its cytotoxicity.Diversity-oriented synthesis of macrocyclic peptidomimetics.Role of natural product diversity in chemical biology.Small molecule microarrays: the first decade and beyond.Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles.A HaloTag-based small molecule microarray screening methodology with increased sensitivity and multiplex capabilities.Identification of biologically active, HIV TAR RNA-binding small molecules using small molecule microarrays.Immunomodulation strategies for preventing vascular disease of the brain and heart: workshop summary.Suppression of the FOXM1 transcriptional programme via novel small molecule inhibitionProteins from an unevolved library of de novo designed sequences bind a range of small molecules.A liquid array platform for the multiplexed analysis of synthetic molecule-protein interactions.Recent discoveries and applications involving small-molecule microarraysA complex task? Direct modulation of transcription factors with small molecules.Genetic and proteomic approaches to identify cancer drug targets.Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression.Small molecule inhibition of FOXM1: How to bring a novel compound into genomic contextDiscovery of RNA Binding Small Molecules Using Small Molecule Microarrays.Developing Spindlin1 small-molecule inhibitors by using protein microarrays.Screening and synthesis: high throughput technologies applied to parasitology.Beauty is skin deep: a surface monolayer perspective on nanoparticle interactions with cells and bio-macromolecules.Enantioselective synthesis on the solid phase.Solid-phase assays for small molecule screening using sol-gel entrapped proteins.Highly enantioselective dearomatizing formal [3+3] cycloaddition reactions of N-acyliminopyridinium ylides with electrophilic enol carbene intermediates.
P2860
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P2860
Discovery of an inhibitor of a transcription factor using small molecule microarrays and diversity-oriented synthesis.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Discovery of an inhibitor of a ...... diversity-oriented synthesis.
@ast
Discovery of an inhibitor of a ...... diversity-oriented synthesis.
@en
type
label
Discovery of an inhibitor of a ...... diversity-oriented synthesis.
@ast
Discovery of an inhibitor of a ...... diversity-oriented synthesis.
@en
prefLabel
Discovery of an inhibitor of a ...... diversity-oriented synthesis.
@ast
Discovery of an inhibitor of a ...... diversity-oriented synthesis.
@en
P2093
P356
P1476
Discovery of an inhibitor of a ...... diversity-oriented synthesis.
@en
P2093
Alykhan F Shamji
Angela N Koehler
Stuart L Schreiber
P304
P356
10.1021/JA0352698
P407
P577
2003-07-01T00:00:00Z