Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation. - Wikidata - awgldk - TriplyDB

Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation.

Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation.

http://www.wikidata.org/entity/Q35808753

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Heterogeneity of white adipose tissue: molecular basis and clinical implications Skeletal Muscle Mitochondrial Bioenergetics and Morphology in High Fat Diet Induced Obesity and Insulin Resistance: Focus on Dietary Fat Source Alzheimer's disease and insulin resistance: translating basic science into clinical applications Consumption of distinct dietary lipids during early pregnancy differentially modulates the expression of microRNAs in mothers and offspring Hepatoprotective role of Sestrin2 against chronic ER stress A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches c-Jun N-terminal kinase mediates mouse liver injury through a novel Sab (SH3BP5)-dependent pathway leading to inactivation of intramitochondrial Src.AMPK-independent inhibition of human macrophage ER stress response by AICAR.Mechanisms of inflammatory responses in obese adipose tissue.Lipid metabolites as metabolic messengers in inter-organ communication.Insulin signaling, resistance, and the metabolic syndrome: insights from mouse models into disease mechanisms.Mechanisms of Liver Injury in Non-Alcoholic Steatohepatitis Trihydrophobin 1 phosphorylation by c-Src regulates MAPK/ERK signaling and cell migration CD14 deficiency impacts glucose homeostasis in mice through altered adrenal tone.A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose tissue inflammation in obesity Alteration of EGFR spatiotemporal dynamics suppresses signal transduction.Role of the mixed-lineage protein kinase pathway in the metabolic stress response to obesity.A gp130-Src-YAP module links inflammation to epithelial regeneration.Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion Unsaturated fatty acids induce non-canonical autophagy.Differential hepatotoxicity of dietary and DNL-derived palmitate in the methionine-choline-deficient model of steatohepatitis.Molecular targets of omega 3 and conjugated linoleic Fatty acids - "micromanaging" cellular response.The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance.p38 MAPK Is Activated but Does Not Play a Key Role during Apoptosis Induction by Saturated Fatty Acid in Human Pancreatic β-Cells.Cell death and cell death responses in liver disease: mechanisms and clinical relevance Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.The inflammation highway: metabolism accelerates inflammatory traffic in obesity.Critical role for mixed-lineage kinase 3 in acetaminophen-induced hepatotoxicity.PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications.Fatty acids from diet and microbiota regulate energy metabolism Group X Secreted Phospholipase A2 Releases ω3 Polyunsaturated Fatty Acids, Suppresses Colitis, and Promotes Sperm Fertility Granulocyte colony-stimulating factor (G-CSF): A saturated fatty acid-induced myokine with insulin-desensitizing properties in humans.Inhibitory effects of omega-3 fatty acids on injury-induced epidermal growth factor receptor transactivation contribute to delayed wound healing.Proteome-wide alterations on adipose tissue from obese patients as age-, diabetes- and gender-specific hallmarks Eicosanoids in metabolic syndrome.Hepatic oleate regulates liver stress response partially through PGC-1α during high-carbohydrate feeding.Dual Roles of Group IID Phospholipase A2 in Inflammation and Cancer Diet-induced obesity mediated by the JNK/DIO2 signal transduction pathway LXRs regulate ER stress and inflammation through dynamic modulation of membrane phospholipid composition.MLK3 promotes metabolic dysfunction induced by saturated fatty acid-enriched diet

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P2860

Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation.

http://www.wikidata.org/entity/Q35808753

description

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Saturated fatty acids induce c ...... ns, leading to JNK activation.

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Eek-Joong Park

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Giovanni Solinas

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Monica Chen

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Ning Li

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Ryan G Holzer

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P2860

GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects

Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism

The challenge of lipid rafts

The concept of lipid domains in membranes

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity

CSK: a protein-tyrosine kinase involved in regulation of src family kinases

The membrane targeting and spatial activation of Src, Yes and Fyn is influenced by palmitoylation and distinct RhoB/RhoD endosome requirements

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

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