The Hippo-YAP pathway: new connections between regulation of organ size and cancer. - Wikidata - awgldk - TriplyDB

The Hippo-YAP pathway: new connections between regulation of organ size and cancer.

The Hippo-YAP pathway: new connections between regulation of organ size and cancer.

http://www.wikidata.org/entity/Q35811415

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PTPN14 is required for the density-dependent control of YAP1 Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction Angiomotin-like proteins associate with and negatively regulate YAP1 The tumor suppressor RASSF1A prevents dephosphorylation of the mammalian STE20-like kinases MST1 and MST2.α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1 Structural and functional analysis of the YAP-binding domain of human TEAD2 Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors Regulation of TAZ in cancer The MST/Hippo Pathway and Cell Death: A Non-Canonical Affair Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development A critical role for NF2 and the Hippo pathway in branching morphogenesis Structural basis of YAP recognition by TEAD4 in the Hippo pathway Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer Hippo/YAP pathway for targeted therapy DLG5 in cell polarity maintenance and cancer development Alteration of TEAD1 expression levels confers apoptotic resistance through the transcriptional up-regulation of Livin The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version Interaction with the Yes-associated protein (YAP) allows TEAD1 to positively regulate NAIP expression Ablation of Rassf2 induces bone defects and subsequent haematopoietic anomalies in mice Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver The related transcriptional enhancer factor-1 isoform, TEAD4(216), can repress vascular endothelial growth factor expression in mammalian cells Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components.Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway.Mutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.Junctional music that the nucleus hears: cell-cell contact signaling and the modulation of gene activity.The Hippo signaling pathway in stem cell biology and cancer Yap1 protein regulates vascular smooth muscle cell phenotypic switch by interaction with myocardin.Genetic control of programmed cell death during animal development.Liver-specific ablation of integrin-linked kinase in mice results in enhanced and prolonged cell proliferation and hepatomegaly after phenobarbital administration.YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway.The biomolecular era for thoracic surgeons: the example of the ESTS Biology Club.LATS2 is de-methylated and overexpressed in nasopharyngeal carcinoma and predicts poor prognosis.Deletion of yes-associated protein (YAP) specifically in cardiac and vascular smooth muscle cells reveals a crucial role for YAP in mouse cardiovascular development.Involvement of members of the cadherin superfamily in cancer Loss of Bicc1 impairs tubulomorphogenesis of cultured IMCD cells by disrupting E-cadherin-based cell-cell adhesion.Prognostic impact of TAZ and β-catenin expression in adenocarcinoma of the esophagogastric junction.KRAS and YAP1 converge to regulate EMT and tumor survival Taz-tead1 links cell-cell contact to zeb1 expression, proliferation, and dedifferentiation in retinal pigment epithelial cells

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The Hippo-YAP pathway: new connections between regulation of organ size and cancer.

http://www.wikidata.org/entity/Q35811415

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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The Hippo-YAP pathway: new connections between regulation of organ size and cancer.

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The Hippo-YAP pathway: new connections between regulation of organ size and cancer.

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The Hippo-YAP pathway: new connections between regulation of organ size and cancer.

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J.CEB.2008.10.001

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Current Opinion in Cell Biology

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The Hippo-YAP pathway: new connections between regulation of organ size and cancer.

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Bin Zhao

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Kun-Liang Guan

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Qun-Ying Lei

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P2860

Molecular interactions between Vestigial and Scalloped promote wing formation in Drosophila

TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

Physical interaction with Yes-associated protein enhances p73 transcriptional activity

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation

Tumor suppressor LATS1 is a negative regulator of oncogene YAP

TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation

Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage

TAZ, a transcriptional modulator of mesenchymal stem cell differentiation

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