G protein-coupled receptor dimerization: function and ligand pharmacology.
about
Scalable rule-based modelling of allosteric proteins and biochemical networksThe orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerizationNuclear localization drives α1-adrenergic receptor oligomerization and signaling in cardiac myocytesLigand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cellsEvidence for a single heptahelical domain being turned on upon activation of a dimeric GPCRInternational Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapyAllostery at G protein-coupled receptor homo- and heteromers: uncharted pharmacological landscapesConstitutive dimerization of the G-protein coupled receptor, neurotensin receptor 1, reconstituted into phospholipid bilayersHigh-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor75 years of opioid research: the exciting but vain quest for the Holy GrailDo orphan G-protein-coupled receptors have ligand-independent functions? New insights from receptor heterodimersNon-traditional roles of G protein-coupled receptors in basic cell biologyVisualization and ligand-induced modulation of dopamine receptor dimerization at the single molecule level.Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells.Relationship of DFG16 to the Rim101p pH response pathway in Saccharomyces cerevisiae and Candida albicansOligomer size of the serotonin 5-hydroxytryptamine 2C (5-HT2C) receptor revealed by fluorescence correlation spectroscopy with photon counting histogram analysis: evidence for homodimers without monomers or tetramersCrosstalk between GABAB and mGlu1a receptors reveals new insight into GPCR signal integrationA Role for the Distal Carboxyl Tails in Generating the Novel Pharmacology and G Protein Activation Profile of and Opioid Receptor Hetero-oligomersActivation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes.D1-D2 dopamine receptor synergy promotes calcium signaling via multiple mechanisms.Electrostatically induced recruitment of membrane peptides into clusters requires ligand binding at both interfacesRequirements and ontology for a G protein-coupled receptor oligomerization knowledge base.Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit.Constitutive dimerization of human serotonin 5-HT4 receptors in living cells.Lipid raft-mediated regulation of G-protein coupled receptor signaling by ligands which influence receptor dimerization: a computational studyRANKL induces heterogeneous DC-STAMP(lo) and DC-STAMP(hi) osteoclast precursors of which the DC-STAMP(lo) precursors are the master fusogens.Synthesis and biological evaluation of bivalent ligands for the cannabinoid 1 receptor.PACAP-induced ERK activation in HEK cells expressing PAC1 receptors involves both receptor internalization and PKC signaling.Toward the Development of Bivalent Ligand Probes of Cannabinoid CB1 and Orexin OX1 Receptor Heterodimers.Dynamic models of G-protein coupled receptor dimers: indications of asymmetry in the rhodopsin dimer from molecular dynamics simulations in a POPC bilayer.The EP1 subtype of prostaglandin E2 receptor: role in keratinocyte differentiation and expression in non-melanoma skin cancer.A novel approach to quantify G-protein-coupled receptor dimerization equilibrium using bioluminescence resonance energy transferChaperoning G protein-coupled receptors: from cell biology to therapeuticsStructure and function of G protein-coupled receptors using NMR spectroscopy.Role of antibodies in developing drugs that target G-protein-coupled receptor dimers.Putative kappa opioid heteromers as targets for developing analgesics free of adverse effects.Physical and functional interaction between CB1 cannabinoid receptors and beta2-adrenoceptorsCrosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation.Programmable nanoscaffolds that control ligand display to a G-protein-coupled receptor in membranes to allow dissection of multivalent effects.N-naphthoyl-beta-naltrexamine (NNTA), a highly selective and potent activator of μ/kappa-opioid heteromers
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P2860
G protein-coupled receptor dimerization: function and ligand pharmacology.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
G protein-coupled receptor dimerization: function and ligand pharmacology.
@ast
G protein-coupled receptor dimerization: function and ligand pharmacology.
@en
type
label
G protein-coupled receptor dimerization: function and ligand pharmacology.
@ast
G protein-coupled receptor dimerization: function and ligand pharmacology.
@en
prefLabel
G protein-coupled receptor dimerization: function and ligand pharmacology.
@ast
G protein-coupled receptor dimerization: function and ligand pharmacology.
@en
P356
P1476
G protein-coupled receptor dimerization: function and ligand pharmacology.
@en
P2093
Graeme Milligan
P356
10.1124/MOL.104.000497.
P577
2004-07-01T00:00:00Z