Carrier-free cellular uptake and the gene-silencing activity of the lipophilic siRNAs is strongly affected by the length of the linker between siRNA and lipophilic group.
about
Visualization of self-delivering hydrophobically modified siRNA cellular internalization.Conjugation and Evaluation of Small Hydrophobic Molecules to Triazole-Linked siRNAs.TNF-α gene knockout in triple negative breast cancer cell line induces apoptosis.Overcoming doxorubicin resistance of cancer cells by Cas9-mediated gene disruption.Carrier-free Gene Silencing by Amphiphilic Nucleic Acid Conjugates in Differentiated Intestinal Cells.Cholesterol-Containing Nuclease-Resistant siRNA Accumulates in Tumors in a Carrier-free Mode and Silences MDR1 Gene.Bioconjugates for targeted delivery of therapeutic oligonucleotides.Oligonucleotide therapeutics: chemistry, delivery and clinical progress.Lipid-Drug Conjugate for Enhancing Drug Delivery.Covalent conjugation of oligonucleotides with cell-targeting ligands.Direct uptake of Antagomirs and efficient knockdown of miRNA in primary B and T lymphocytes.Chemical modifications of nucleic acid drugs and their delivery systems for gene-based therapy.In Vivo RNAi Efficacy of Palmitic Acid-Conjugated Dicer-Substrate siRNA in a Subcutaneous Tumor Mouse Model.Synthesis of a cholesteryl-HEG phosphoramidite derivative and its application to lipid-conjugates of the anti-HIV 5'TGGGAG³' Hotoda's sequence.Conjugation of DNA with Biomolecules and Nanoparticles
P2860
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P2860
Carrier-free cellular uptake and the gene-silencing activity of the lipophilic siRNAs is strongly affected by the length of the linker between siRNA and lipophilic group.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Carrier-free cellular uptake a ...... en siRNA and lipophilic group.
@ast
Carrier-free cellular uptake a ...... en siRNA and lipophilic group.
@en
type
label
Carrier-free cellular uptake a ...... en siRNA and lipophilic group.
@ast
Carrier-free cellular uptake a ...... en siRNA and lipophilic group.
@en
prefLabel
Carrier-free cellular uptake a ...... en siRNA and lipophilic group.
@ast
Carrier-free cellular uptake a ...... en siRNA and lipophilic group.
@en
P2093
P2860
P356
P1476
Carrier-free cellular uptake a ...... en siRNA and lipophilic group.
@en
P2093
Aliya G Venyaminova
Elena L Chernolovskaya
Iiya S Dovydenko
Ivan V Chernikov
Marina A Zenkova
Natalya S Petrova
P2860
P304
P356
10.1093/NAR/GKR1002
P407
P577
2011-11-10T00:00:00Z