CD4/CD8-lineage differentiation in the thymus: from nuclear effectors to membrane signals.
about
Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signalingGATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiationThemis, a T cell-specific protein important for late thymocyte developmentInterferon-gamma and interleukin-4 reciprocally regulate CD8 expression in CD8+ T cellsGlobal mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cellsExpression of the SNARE protein SNAP-23 is essential for cell survivalATP-dependent chromatin remodeling in T cellsDistinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cellsPresenilins regulate alphabeta T cell development by modulating TCR signalingLKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selectionThe transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gammaThe transcription factor Ets1 is important for CD4 repression and Runx3 up-regulation during CD8 T cell differentiation in the thymus.Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development.Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors.T-cell signaling regulated by the Tec family kinase, Itk.TCF1 and beta-catenin regulate T cell development and functionDevelopment of CD4+ T cells expressing a nominally MHC class I-restricted T cell receptor by two different mechanisms.Groucho/transducin-like Enhancer-of-split (TLE)-dependent and -independent transcriptional regulation by Runx3.Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice.The NF-κB1 transcription factor prevents the intrathymic development of CD8 T cells with memory propertiesThe general transcription factor TAF7 is essential for embryonic development but not essential for the survival or differentiation of mature T cells.Hematopoiesis and thymic apoptosis are not affected by the loss of Cdk2.The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes.Nucleoprotein structure of the CD4 locus: implications for the mechanisms underlying CD4 regulation during T cell developmentBeta-catenin expression enhances IL-7 receptor signaling in thymocytes during positive selection.Beta-catenin regulates positive selection of thymocytes but not lineage commitment.c-Rel: shaping CD4 regulatory T cell development in unexpected ways.TAF7: traffic controller in transcription initiation.What Happens in the Thymus Does Not Stay in the Thymus: How T Cells Recycle the CD4+-CD8+ Lineage Commitment Transcriptional Circuitry To Control Their Function.Cellular and molecular requirements for the selection of in vitro-generated CD8 T cells reveal a role for NotchCD44 expression positively correlates with Foxp3 expression and suppressive function of CD4+ Treg cells.Fighting Viral Infections and Virus-Driven Tumors with Cytotoxic CD4+ T Cells.NK cell development, homeostasis and function: parallels with CD8⁺ T cells.NF-κB subunit specificity in hemopoiesis.Diverse T-cell differentiation potentials of human fetal thymus, fetal liver, cord blood and adult bone marrow CD34 cells on lentiviral Delta-like-1-modified mouse stromal cells.Noncanonical mode of ERK action controls alternative αβ and γδ T cell lineage fates.Differential chromatin looping regulates CD4 expression in immature thymocytes.c-Myb regulates lineage choice in developing thymocytes via its target gene Gata3.SAP protein-dependent natural killer T-like cells regulate the development of CD8(+) T cells with innate lymphocyte characteristics.Thpok-independent repression of Runx3 by Gata3 during CD4+ T-cell differentiation in the thymus.
P2860
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P2860
CD4/CD8-lineage differentiation in the thymus: from nuclear effectors to membrane signals.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
CD4/CD8-lineage differentiatio ...... effectors to membrane signals.
@ast
CD4/CD8-lineage differentiatio ...... effectors to membrane signals.
@en
type
label
CD4/CD8-lineage differentiatio ...... effectors to membrane signals.
@ast
CD4/CD8-lineage differentiatio ...... effectors to membrane signals.
@en
prefLabel
CD4/CD8-lineage differentiatio ...... effectors to membrane signals.
@ast
CD4/CD8-lineage differentiatio ...... effectors to membrane signals.
@en
P2860
P356
P1476
CD4/CD8-lineage differentiatio ...... effectors to membrane signals.
@en
P2093
Rémy Bosselut
P2860
P2888
P304
P356
10.1038/NRI1392
P577
2004-07-01T00:00:00Z
P6179
1036642850