Chemically induced renal tubule tumors in the laboratory rat and mouse: review of the NCI/NTP database and categorization of renal carcinogens based on mechanistic information.
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Ochratoxin A: 50 Years of ResearchMechanisms of chemical carcinogenesis in the kidneysModulation of key regulators of mitosis linked to chromosomal instability is an early event in ochratoxin A carcinogenicityDeriving a data-based interspecies assessment factor using the NOAEL and the benchmark dose approach.Histological investigation of diagnostically challenging tubule profiles in advanced chronic progressive nephropathy (CPN) in the fischer 344 RaT.A data-based assessment of alternative strategies for identification of potential human cancer hazards.Molecular characterization of preneoplastic lesions provides insight on the development of renal tumors.Spontaneous occurrence of a distinctive renal tubule tumor phenotype in rat carcinogenicity studies conducted by the national toxicology programAssociation of advanced chronic progressive nephropathy (CPN) with renal tubule tumors and precursor hyperplasia in control F344 rats from two-year carcinogenicity studies.A pilot study of nuclear instability in archived renal and upper urinary tract tumours with putative ochratoxin aetiology.alpha 2u-globulin nephropathy and renal tumors in national toxicology program studiesHealth risk assessment of ochratoxin A for all age-sex strata in a market economyRenal Cell Carcinomas in Vinylidene Chloride-exposed Male B6C3F1 Mice Are Characterized by Oxidative Stress and TP53 Pathway Dysregulation.Maternal-Fetal Cancer Risk Assessment of Ochratoxin A during Pregnancy.Hydroquinone: an evaluation of the human risks from its carcinogenic and mutagenic properties.Binding of ochratoxin A to a urinary globulin: a new concept to account for gender difference in rat nephrocarcinogenic responses.Toxicity and carcinogenicity of methyl isobutyl ketone in F344N rats and B6C3F1 mice following 2-year inhalation exposure.A comparison of rat chronic progressive nephropathy with human renal disease-implications for human risk assessment.Ochratoxin A and aristolochic acid involvement in nephropathies and associated urothelial tract tumours.Ochratoxin a and mitotic disruption: mode of action analysis of renal tumor formation by ochratoxin A.Human health screening level risk assessments of tertiary-butyl acetate (TBAC): calculated acute and chronic reference concentration (RfC) and Hazard Quotient (HQ) values based on toxicity and exposure scenario evaluations.Risk assessments for chronic exposure of children and prospective parents to ethylbenzene (CAS No. 100-41-4).Successful integration of nonclinical and clinical findings in interpreting the clinical relevance of rodent neoplasia with a new chemical entity.Mycotoxins as human carcinogens-the IARC Monographs classification.Ochratoxin A: apoptosis and aberrant exit from mitosis due to perturbation of microtubule dynamics?Nonclinical safety of the sodium-glucose cotransporter 2 inhibitor empagliflozin.Expression patterns of cell cycle proteins in the livers of rats treated with hepatocarcinogens for 28 days.An extensive epidemiological investigation of a kidney cancer cluster in a chemical plant: what have we learned?A Predominant Oxidative Renal Metabolite of Empagliflozin in Male Mice Is Cytotoxic in Mouse Renal Tubular Cells but not Genotoxic.Chronic progressive nephropathy in male F344 rats in 90-day toxicity studies: its occurrence and association with renal tubule tumors in subsequent 2-year bioassays.Early onset of spontaneous renal preneoplastic and neoplastic lesions in young conventional rats in toxicity studies.Renal tumors in male rats following long-term administration of bazedoxifene, a tissue-selective estrogen receptor modulator.14C-labeled pulegone and metabolites binding to alpha2u-globulin in kidneys of male F-344 rats.Cellular distribution of cell cycle-related molecules in the renal tubules of rats treated with renal carcinogens for 28 days: relationship between cell cycle aberration and carcinogenesis.Toxicity of the mycotoxin ochratoxin A in the light of recent data
P2860
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P2860
Chemically induced renal tubule tumors in the laboratory rat and mouse: review of the NCI/NTP database and categorization of renal carcinogens based on mechanistic information.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Chemically induced renal tubul ...... ed on mechanistic information.
@ast
Chemically induced renal tubul ...... ed on mechanistic information.
@en
type
label
Chemically induced renal tubul ...... ed on mechanistic information.
@ast
Chemically induced renal tubul ...... ed on mechanistic information.
@en
prefLabel
Chemically induced renal tubul ...... ed on mechanistic information.
@ast
Chemically induced renal tubul ...... ed on mechanistic information.
@en
P2860
P1476
Chemically induced renal tubul ...... ed on mechanistic information.
@en
P2093
Edward A Lock
Gordon C Hard
P2860
P304
P356
10.1080/10408440490265210
P407
P577
2004-05-01T00:00:00Z