Trans-SNARE complex assembly and yeast vacuole membrane fusion.
about
The Secret Life of Tethers: The Role of Tethering Factors in SNARE Complex RegulationMembrane trafficking and phagosome maturation during the clearance of apoptotic cellsThe V-ATPase proteolipid cylinder promotes the lipid-mixing stage of SNARE-dependent fusion of yeast vacuoles.Reconstituted membrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperonesPhosphoinositides and SNARE chaperones synergistically assemble and remodel SNARE complexes for membrane fusionHOPS prevents the disassembly of trans-SNARE complexes by Sec17p/Sec18p during membrane fusionThe Exocyst Subunit Sec6 Interacts with Assembled Exocytic SNARE ComplexesPhosphatidic Acid Sequesters Sec18p from cis-SNARE Complexes to Inhibit PrimingHOPS proofreads the trans-SNARE complex for yeast vacuole fusionThe yeast ATP-binding cassette (ABC) transporter Ycf1p enhances the recruitment of the soluble SNARE Vam7p to vacuoles for efficient membrane fusion.The Central Polybasic Region of the Soluble SNARE (Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor) Vam7 Affects Binding to Phosphatidylinositol 3-Phosphate by the PX (Phox Homology) Domain.Yeast lipin 1 orthologue pah1p regulates vacuole homeostasis and membrane fusion.Role of Rab GTPases in membrane traffic and cell physiologyIn vitro assay using engineered yeast vacuoles for neuronal SNARE-mediated membrane fusion.Membranes linked by trans-SNARE complexes require lipids prone to non-bilayer structure for progression to fusion.HOPS interacts with Apl5 at the vacuole membrane and is required for consumption of AP-3 transport vesicles.HOPS initiates vacuole docking by tethering membranes before trans-SNARE complex assembly.Class IA phosphatidylinositol 3-kinase p110α regulates phagosome maturation.LegC3, an effector protein from Legionella pneumophila, inhibits homotypic yeast vacuole fusion in vivo and in vitroVibrio effector protein VopQ inhibits fusion of V-ATPase-containing membranes.The Vps39-like TRAP1 is an effector of Rab5 and likely the missing Vps3 subunit of human CORVETSec17 can trigger fusion of trans-SNARE paired membranes without Sec18.Vacuolar SNARE protein transmembrane domains serve as nonspecific membrane anchors with unequal roles in lipid mixing.SNAREs support atlastin-mediated homotypic ER fusion in Saccharomyces cerevisiaeAssays of vacuole fusion resolve the stages of docking, lipid mixing, and content mixingExcess vacuolar SNAREs drive lysis and Rab bypass fusionImpairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33A(D251E) mutation.Sec18p and Vam7p remodel trans-SNARE complexes to permit a lipid-anchored R-SNARE to support yeast vacuole fusion.Docking of liposomes to planar surfaces mediated by trans-SNARE complexesThe yeast vacuolar ABC transporter Ybt1p regulates membrane fusion through Ca2+ transport modulationThe lipid composition and physical properties of the yeast vacuole affect the hemifusion-fusion transition.Capture and release of partially zipped trans-SNARE complexes on intact organelles.The yeast lysosome-like vacuole: endpoint and crossroadsMembrane lysis during biological membrane fusion: collateral damage by misregulated fusion machines.Minimal membrane docking requirements revealed by reconstitution of Rab GTPase-dependent membrane fusion from purified components.CAPS drives trans-SNARE complex formation and membrane fusion through syntaxin interactionsHOPS catalyzes the interdependent assembly of each vacuolar SNARE into a SNARE complex.New links between vesicle coats and Rab-mediated vesicle targeting.Tethering complexes in the endocytic pathway: CORVET and HOPS.The membrane domain of vacuolar H(+)ATPase: a crucial player in neurotransmitter exocytotic release.
P2860
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P2860
Trans-SNARE complex assembly and yeast vacuole membrane fusion.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Trans-SNARE complex assembly and yeast vacuole membrane fusion.
@ast
Trans-SNARE complex assembly and yeast vacuole membrane fusion.
@en
type
label
Trans-SNARE complex assembly and yeast vacuole membrane fusion.
@ast
Trans-SNARE complex assembly and yeast vacuole membrane fusion.
@en
prefLabel
Trans-SNARE complex assembly and yeast vacuole membrane fusion.
@ast
Trans-SNARE complex assembly and yeast vacuole membrane fusion.
@en
P2860
P356
P1476
Trans-SNARE complex assembly and yeast vacuole membrane fusion
@en
P2093
William T Wickner
P2860
P304
P356
10.1073/PNAS.0702290104
P407
P577
2007-05-14T00:00:00Z