Keap1-Nrf2 activation in the presence and absence of DJ-1.
about
DJ-1 induces thioredoxin 1 expression through the Nrf2 pathwayThe Nrf2/HO-1 Axis in Cancer Cell Growth and ChemoresistanceEmerging functional cross-talk between the Keap1-Nrf2 system and mitochondriaCross Talk between Two Antioxidant Systems, Thioredoxin and DJ-1: Consequences for CancerEmerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotectionMolecular basis for vulnerability to mitochondrial and oxidative stress in a neuroendocrine CRI-G1 cell lineDecreased DJ-1 leads to impaired Nrf2-regulated antioxidant defense and increased UV-A-induced apoptosis in corneal endothelial cells.DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress.The endotoxin-induced neuroinflammation model of Parkinson's disease.The role of cysteine oxidation in DJ-1 function and dysfunction.ATF3 protects pulmonary resident cells from acute and ventilator-induced lung injury by preventing Nrf2 degradation.Role of nuclear factor erythroid 2-related factor 2 in the oxidative stress-dependent hypertension associated with the depletion of DJ-1A DJ-1 Based Peptide Attenuates Dopaminergic Degeneration in Mice Models of Parkinson's Disease via Enhancing Nrf2.Loss of DJ-1 elicits retinal abnormalities, visual dysfunction, and increased oxidative stress in mice.Absence of DJ-1 causes age-related retinal abnormalities in association with increased oxidative stress.Thiol-redox signaling, dopaminergic cell death, and Parkinson's diseaseActivation of the Nrf2-ARE pathway by siRNA knockdown of Keap1 reduces oxidative stress and provides partial protection from MPTP-mediated neurotoxicity.Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model.NFE2L2 variations reduce antioxidant response in patients with Parkinson disease.SOD1 and DJ-1 converge at Nrf2 pathway: a clue for antioxidant therapeutic potential in neurodegenerationOverexpression of DJ-1 reduces oxidative stress and attenuates hypoxia/reoxygenation injury in NRK-52E cells exposed to high glucose.Tert-buthylhydroquinone pre-conditioning exerts dual effects in old female rats exposed to 3-nitropropionic acid.Antioxidant protection: A promising therapeutic intervention in neurodegenerative disease.Role of the Nrf2 signaling system in health and disease.The role of DJ-1 in the oxidative stress cell death cascade after strokeAstrocytes in neurodegenerative disease.Computational genomic analysis of PARK7 interactome reveals high BBS1 gene expression as a prognostic factor favoring survival in malignant pleural mesothelioma.The emerging role of Nrf2 in mitochondrial functionNrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001A myristoylated cell-penetrating peptide bearing a transferrin receptor-targeting sequence for neuro-targeted siRNA delivery.The Parkinson's-associated protein DJ-1 regulates the 20S proteasome.Knocking out DJ-1 attenuates astrocytes neuroprotection against 6-hydroxydopamine toxicity.HO-1 Induction in Cancer Progression: A Matter of Cell Adaptation.Global stress response in a prokaryotic model of DJ-1-associated Parkinsonism.Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease.The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease.DJ-1 ameliorates ischemic cell death in vitro possibly via mitochondrial pathway.Evidence of oxidative stress in young and aged DJ-1-deficient mice.The Multifaceted Roles of DJ-1 as an Antioxidant.DJ-1 Protects Breast Cancer Cells Against 2'-Benzoyloxycinnamaldehyde-induced Oxidative Stress Independent of Nrf2.
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P2860
Keap1-Nrf2 activation in the presence and absence of DJ-1.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Keap1-Nrf2 activation in the presence and absence of DJ-1.
@ast
Keap1-Nrf2 activation in the presence and absence of DJ-1.
@en
type
label
Keap1-Nrf2 activation in the presence and absence of DJ-1.
@ast
Keap1-Nrf2 activation in the presence and absence of DJ-1.
@en
prefLabel
Keap1-Nrf2 activation in the presence and absence of DJ-1.
@ast
Keap1-Nrf2 activation in the presence and absence of DJ-1.
@en
P2093
P2860
P1476
Keap1-Nrf2 activation in the presence and absence of DJ-1.
@en
P2093
Delinda A Johnson
Jeffrey A Johnson
P2860
P304
P356
10.1111/J.1460-9568.2010.07138.X
P407
P577
2010-03-03T00:00:00Z