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A Temporal Model of Human IgE and IgG Antibody FunctionAntibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized miceThe role of the T follicular helper cells in allergic diseaseRegulatory constraints in the generation and differentiation of IgE-expressing B cellsThe Developmental History of IgE and IgG4 Antibodies in Relation to Atopy, Eosinophilic Esophagitis, and the Modified TH2 Response.AID-induced remodeling of immunoglobulin genes and B cell fate.B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans.Suppression of IgE B cells and IgE binding to Fc(epsilon)RI by gene therapy with single-chain anti-IgE.IgE recognition patterns of profilin, PR-10, and tropomyosin panallergens tested in 3,113 allergic patients by allergen microarray-based technology.Limited humoral immunoglobulin E memory influences serum immunoglobulin E levels in blood.Rethinking the role of immunoglobulin E and its high-affinity receptor: new insights into allergy and beyond.IgE-associated IGHV genes from venom and peanut allergic individuals lack mutational evidence of antigen selection.Both the variability and level of mouse allergen exposure influence the phenotype of the immune response in workers at a mouse facility.Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination.Sequential class switching is required for the generation of high affinity IgE antibodies.The Extracellular Domains of IgG1 and T Cell-Derived IL-4/IL-13 Are Critical for the Polyclonal Memory IgE Response In VivoReprogramming IgH isotype-switched B cells to functional-grade induced pluripotent stem cellsImbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination.Intrinsic properties of germinal center-derived B cells promote their enhanced class switching to IgE.Human B-cell isotype switching origins of IgEItch-/- alphabeta and gammadelta T cells independently contribute to autoimmunity in Itchy miceA randomized trial of the efficacy and safety of quilizumab in adults with inadequately controlled allergic asthma.B cells establish, but do not maintain, long-lived murine anti-peanut IgE(a).Immune responses to inhalant allergens.IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice.Immunogenetic characteristics of immunoglobulin E in allergic disease.The distinctive germinal center phase of IgE+ B lymphocytes limits their contribution to the classical memory response.Ontogeny of human IgE-expressing B cells and plasma cellsDiminished allergic disease in patients with STAT3 mutations reveals a role for STAT3 signaling in mast cell degranulation.Regulation of B cell fate by chronic activity of the IgE B cell receptor.IgE immunotherapy: a novel concept with promise for the treatment of cancer.Heterogeneity in the differentiation and function of memory B cellsInnate B cell helpers reveal novel types of antibody responses.What is the source of serum allergen-specific IgE?Genetic regulation of immunoglobulin E level in different pathological states: integration of mouse and human genetics.Local immunoglobulin e in the nasal mucosa: clinical implications.Regulation of IgE Responses by γδ T Cells.T follicular helper (Tfh ) cells in normal immune responses and in allergic disorders.Nonallergic rhinitis and lower airway disease.Human memory B cells.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Unique maturation program of the IgE response in vivo
@ast
Unique maturation program of the IgE response in vivo
@en
type
label
Unique maturation program of the IgE response in vivo
@ast
Unique maturation program of the IgE response in vivo
@en
prefLabel
Unique maturation program of the IgE response in vivo
@ast
Unique maturation program of the IgE response in vivo
@en
P2093
P2860
P1433
P1476
Unique maturation program of the IgE response in vivo
@en
P2093
Agustin Erazo
Ana P Guarnieri Christ
Juan J Lafaille
Maria A Curotto de Lafaille
Monica Leung
Nino Kutchukhidze
P2860
P304
P356
10.1016/J.IMMUNI.2006.12.006
P407
P577
2007-02-08T00:00:00Z