Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes. - Wikidata - awgldk - TriplyDB

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes.

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes.

http://www.wikidata.org/entity/Q33656152

about

Sequences of human immunoglobulin switch regions: implications for recombination and transcription T-bet regulates IgG class switching and pathogenic autoantibody production Interleukin 5 (IL-5) provides a signal that is required in addition to IL-4 for isotype switching to immunoglobulin (Ig) G1 and IgE.Somatic mutations in the Ig variable region genes and expression of novel Cmu-germline transcripts in a B-lymphoma cell line ("Farage") not producing Ig polypeptide chains.Molecular characterization of germ-line immunoglobulin A transcripts produced during transforming growth factor type beta-induced isotype switching The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins Synthesis of germ-line gamma 1 immunoglobulin heavy-chain transcripts in resting B cells: induction by interleukin 4 and inhibition by interferon gamma.Transcription through a simple DNA repeat blocks replication elongation CD300f:IL-5 cross-talk inhibits adipose tissue eosinophil homing and subsequent IL-4 production Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination.Nippocystatin, a cysteine protease inhibitor from Nippostrongylus brasiliensis, inhibits antigen processing and modulates antigen-specific immune response.One cytokine, two isotypes: a trojan horse, pandora's box, and an evolving paradigm.Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.Human antibodies from transgenic mice.IgE secretion by Epstein-Barr virus-infected purified human B lymphocytes is stimulated by interleukin 4 and suppressed by interferon gamma Negative regulation of activation-induced cytidine deaminase in B cells Downstream boundary of chromosomal R-loops at murine switch regions: implications for the mechanism of class switch recombination.Accessibility control and machinery of immunoglobulin class switch recombination.What role for AID: mutator, or assembler of the immunoglobulin mutasome?Clonal variants of hybridoma cells that switch isotype at a high frequency Isotype switching in CD5 B cells.T-cell receptor V elements regulate murine IgE production and airways responsiveness.The lamina propria: a dynamic, complex mucosal compartment. An overview.Demonstration of a divergent transcript from the bidirectional heavy chain immunoglobulin promoter VH441 in B-cells.Unique maturation program of the IgE response in vivo Mice lacking Sμ tandem repeats maintain RNA polymerase patterns but exhibit histone modification pattern shifts linked to class switch site locations.The phosphoinositide 3-kinase signaling pathway in normal and malignant B cells: activation mechanisms, regulation and impact on cellular functions.An antisense oligonucleotide complementary to a sequence in I gamma 2b increases gamma 2b germline transcripts, stimulates B cell DNA synthesis, and inhibits immunoglobulin secretion.Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching.Combinatorial mechanisms regulating AID-dependent DNA deamination: interacting proteins and post-translational modifications.Interleukin 4 induces changes in the chromatin structure of the gamma 1 switch region in resting B cells before switch recombination.Ordered rearrangement of variable region genes of the T cell receptor gamma locus correlates with transcription of the unrearranged genes.Interleukin 5 induces S mu-S gamma 1 DNA rearrangement in B cells activated with dextran-anti-IgD antibodies and interleukin 4: a three component model for Ig class switching.Independent regulation of DNA recombination and immunoglobulin (Ig) secretion during isotype switching to IgG1 and IgE Anti-immunoglobulin E treatment decreases worm burden and egg production in Schistosoma mansoni-infected normal and interferon gamma knockout mice.Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50.Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse.Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers.Diversity of cytokine synthesis and function of mouse CD4+ T cells.Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter.

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P2860

Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes.

http://www.wikidata.org/entity/Q33656152

description

1988 nî lūn-bûn

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1988 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1988 թվականի հոտեմբերին հրատարակված գիտական հոդված

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1988年の論文

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1988年論文

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1988年論文

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1988年論文

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1988年論文

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1988年論文

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1988年论文

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name

Immunoglobulin heavy-chain swi ...... ts from constant-region genes.

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Immunoglobulin heavy-chain swi ...... ts from constant-region genes.

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Immunoglobulin heavy-chain swi ...... ts from constant-region genes.

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Immunoglobulin heavy-chain swi ...... ts from constant-region genes.

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Immunoglobulin heavy-chain swi ...... ts from constant-region genes.

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Immunoglobulin heavy-chain swi ...... ts from constant-region genes.

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PNAS.85.20.7704

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Proceedings of the National Academy of Sciences of the United States of America

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Immunoglobulin heavy-chain swi ...... ts from constant-region genes.

@en

P2093

E Severinson

http://www.w3.org/2001/XMLSchema#string

G Radcliffe

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J Nietupski

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J Stavnezer

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L Berggren

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R Sitia

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Y C Lin

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P2860

Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching.

Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter.

Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II.

Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes.

Cloning of mouse immunoglobulin epsilon gene and its location within the heavy chain gene cluster.

T cell-derived B cell differentiation factor(s). Effect on the isotype switch of murine B cells

Clonal analysis of B cells induced to secrete IgG by T cell-derived lymphokine(s)

Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes.

Purification to homogeneity of B cell stimulating factor. A molecule that stimulates proliferation of multiple lymphokine-dependent cell lines.

Differential regulation of IgG1 and IgE synthesis by interleukin 4.

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7704-7708

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10.1073/PNAS.85.20.7704

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20

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85

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1988-10-01T00:00:00Z

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20695849

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2459714

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282261

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