Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules.
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Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase–dependent DC functions and regulates experimental graft-versus-host disease in miceSecretion without GolgiP2X7 receptors regulate multiple types of membrane trafficking responses and non-classical secretion pathwaysNew Therapeutic Approaches in Polycythemia VeraCysteine Oxidation Targets Peroxiredoxins 1 and 2 for Exosomal Release through a Novel Mechanism of Redox-Dependent SecretionThe pannexin 1 channel activates the inflammasome in neurons and astrocytesMonocyte derived microvesicles deliver a cell death message via encapsulated caspase-1.Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury.Microtubule acetylation and stability may explain alcohol-induced alterations in hepatic protein trafficking.The microtubule-associated protein EB1 links AIM2 inflammasomes with autophagy-dependent secretion.The histone deacetylase inhibitor ITF2357 selectively targets cells bearing mutated JAK2(V617F).Increased PRAME-specific CTL killing of acute myeloid leukemia cells by either a novel histone deacetylase inhibitor chidamide alone or combined treatment with decitabine.Specific inhibition of histone deacetylase 8 reduces gene expression and production of proinflammatory cytokines in vitro and in vivoHistone deacetylase inhibitors for treating a spectrum of diseases not related to cancerEffects of the histone deacetylase inhibitor ITF2357 in autoinflammatory syndromes.Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat).The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet β cells in vivo and in vitro.NLRP7, a nucleotide oligomerization domain-like receptor protein, is required for normal cytokine secretion and co-localizes with Golgi and the microtubule-organizing center.Givinostat inhibition of hepatic stellate cell proliferation and protein acetylation.Trichostatin A abrogates airway constriction, but not inflammation, in murine and human asthma models.Tissue factor pathway inhibitor attenuates the progression of malignant pleural mesothelioma in nude mice.Mononuclear Phagocyte-Derived Microparticulate Caspase-1 Induces Pulmonary Vascular Endothelial Cell Injury.The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro.ITF2357 transactivates Id3 and regulate TGFβ/BMP7 signaling pathways to attenuate corneal fibrosis.ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1beta and IL-18 secretion in an autocrine wayVASCULAR INFLAMMATION AND ATHEROGENESIS ARE ACTIVATED VIA RECEPTORS FOR PAMPs AND SUPPRESSED BY REGULATORY T CELLS.Protective responses to sublytic complement in the retinal pigment epitheliumEpigenetic therapy in myeloproliferative neoplasms: evidence and perspectives.Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?Therapy for latent HIV-1 infection: the role of histone deacetylase inhibitors.HDAC inhibition in rheumatoid arthritis and juvenile idiopathic arthritis.Understanding the mechanism of IL-1β secretionNon-classical membrane trafficking processes galore.Arrivals and departures at the plasma membrane: direct and indirect transport routes.P2X7 receptor regulation of non-classical secretion from immune effector cellsInflammasomes in wound healing and fibrosis.Toxicological and metabolic considerations for histone deacetylase inhibitors.The Roles of Lysosomes in Inflammation and Autoimmune Diseases.N-Alkyl-Substituted Isatins Enhance P2X7 Receptor-Induced Interleukin-1β Release from Murine Macrophages.Histone deacetylase inhibitor givinostat: the small-molecule with promising activity against therapeutically challenging haematological malignancies.
P2860
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P2860
Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Histone deacetylase inhibitors ...... sosomes: role of microtubules.
@ast
Histone deacetylase inhibitors ...... sosomes: role of microtubules.
@en
type
label
Histone deacetylase inhibitors ...... sosomes: role of microtubules.
@ast
Histone deacetylase inhibitors ...... sosomes: role of microtubules.
@en
prefLabel
Histone deacetylase inhibitors ...... sosomes: role of microtubules.
@ast
Histone deacetylase inhibitors ...... sosomes: role of microtubules.
@en
P2093
P2860
P1433
P1476
Histone deacetylase inhibitors ...... sosomes: role of microtubules.
@en
P2093
Claudia Semino
Gianluca Fossati
Paolo Mascagni
Sara Tassi
Sonia Carta
P2860
P304
P356
10.1182/BLOOD-2006-03-014126
P407
P577
2006-05-09T00:00:00Z