C/EBPalpha directs monocytic commitment of primary myeloid progenitors. - Wikidata - awgldk - TriplyDB

C/EBPalpha directs monocytic commitment of primary myeloid progenitors.

C/EBPalpha directs monocytic commitment of primary myeloid progenitors.

http://www.wikidata.org/entity/Q35849912

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C/EBPα Dysregulation in AML and ALL Reintroduction of CEBPA in MN1-overexpressing hematopoietic cells prevents their hyperproliferation and restores myeloid differentiation Epigenetic Regulation of Immunological Alterations Following Prenatal Exposure to Marijuana Cannabinoids and its Long Term Consequences in Offspring Twist-2 controls myeloid lineage development and function The Epstein-Barr virus BZLF1 protein inhibits tumor necrosis factor receptor 1 expression through effects on cellular C/EBP proteins Bcl3 prevents acute inflammatory lung injury in mice by restraining emergency granulopoiesis.The multifaceted functions of C/EBPα in normal and malignant haematopoiesis.Proteomic discovery of Max as a novel interacting partner of C/EBPalpha: a Myc/Max/Mad link.A Comprehensive Profile of ChIP-Seq-Based PU.1/Spi1 Target Genes in Microglia Differential effects of nitrostyrene derivatives on myelopoiesis involve regulation of C/EBPα and p38MAPK activity.Granulopoiesis requires increased C/EBPα compared to monopoiesis, correlated with elevated Cebpa in immature G-CSF receptor versus M-CSF receptor expressing cells.SHP2 tyrosine phosphatase stimulates CEBPA gene expression to mediate cytokine-dependent granulopoiesis IL-32θ inhibits monocytic differentiation of leukemia cells by attenuating expression of transcription factor PU.1.Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis.CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer binding protein alpha Sex, stroke, and inflammation: the potential for estrogen-mediated immunoprotection in stroke.C/EBPalpha binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment.Genome-scale definition of the transcriptional programme associated with compromised PU.1 activity in acute myeloid leukaemia.Transcriptional repression of c-Myb and GATA-2 is involved in the biologic effects of C/EBPalpha in p210BCR/ABL-expressing cells.C/EBPalpha induces PU.1 and interacts with AP-1 and NF-kappaB to regulate myeloid development Socs3 maintains the specificity of biological responses to cytokine signals during granulocyte and macrophage differentiation.Transcriptional dysregulation during myeloid transformation in AML.NF-kappa B p50 regulates C/EBP alpha expression and inflammatory cytokine-induced neutrophil production.M-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification.Distinct microRNA expression profile and targeted biological pathways in functional myeloid-derived suppressor cells induced by Δ9-tetrahydrocannabinol in vivo: regulation of CCAAT/enhancer-binding protein α by microRNA-690.The versatility of haematopoietic stem cells: implications for leukaemia.Regulation of monocyte differentiation by specific signaling modules and associated transcription factor networks.C/EBP alpha:AP-1 leucine zipper heterodimers bind novel DNA elements, activate the PU.1 promoter and direct monocyte lineage commitment more potently than C/EBP alpha homodimers or AP-1 C/EBPα in normal and malignant myelopoiesis.The generation and properties of human macrophage populations from hemopoietic stem cells.Understanding chronic neutropenia: life is short.2014 Jeffrey M. Hoeg Award Lecture: Transcriptional Control of Monocyte Development.C/EBPα deregulation as a paradigm for leukemogenesis.C/EBPalpha and C/EBPvarepsilon induce the monocytic differentiation of myelomonocytic cells with the MLL-chimeric fusion gene.C/EBPalpha or C/EBPalpha oncoproteins regulate the intrinsic and extrinsic apoptotic pathways by direct interaction with NF-kappaB p50 bound to the bcl-2 and FLIP gene promoters.The role of translation initiation regulation in haematopoiesis.The effects of 1,25-dihydroxyvitamin D3 on in vitro human NK cell development from hematopoietic stem cells.Dysregulated gene expression during hematopoietic differentiation from human embryonic stem cells.BCR-ABL promotes neutrophil differentiation in the chronic phase of chronic myeloid leukemia by downregulating c-Jun expression.

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P2860

C/EBPalpha directs monocytic commitment of primary myeloid progenitors.

http://www.wikidata.org/entity/Q35849912

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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2006年论文

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2006年论文

@zh-cn

name

C/EBPalpha directs monocytic commitment of primary myeloid progenitors.

@ast

C/EBPalpha directs monocytic commitment of primary myeloid progenitors.

@en

type

label

C/EBPalpha directs monocytic commitment of primary myeloid progenitors.

@ast

C/EBPalpha directs monocytic commitment of primary myeloid progenitors.

@en

prefLabel

C/EBPalpha directs monocytic commitment of primary myeloid progenitors.

@ast

C/EBPalpha directs monocytic commitment of primary myeloid progenitors.

@en

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BLOOD-2005-12-008763

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C/EBPalpha directs monocytic commitment of primary myeloid progenitors.

@en

P2093

Alan D Friedman

http://www.w3.org/2001/XMLSchema#string

Curt I Civin

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Dehua Wang

http://www.w3.org/2001/XMLSchema#string

Jenice D'Costa

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P2860

A novel human CCAAT/enhancer binding protein gene, C/EBPepsilon, is expressed in cells of lymphoid and myeloid lineages and is localized on chromosome 14q11.2 close to the T-cell receptor alpha/delta locus

Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells

C/EBPalpha deficiency results in hyperproliferation of hematopoietic progenitor cells and disrupts macrophage development in vitro and in vivo

Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors

Stepwise reprogramming of B cells into macrophages.

Downregulation of c-Jun expression by transcription factor C/EBPalpha is critical for granulocytic lineage commitment

C/EBPalpha determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiation

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice

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1223-1229

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10.1182/BLOOD-2005-12-008763

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4

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