Linkage between reovirus-induced apoptosis and inhibition of cellular DNA synthesis: role of the S1 and M2 genes.
about
Apoptosis in animal models of virus-induced diseaseSerotype-Specific Killing of Large Cell Carcinoma Cells by Reovirus.Independent regulation of reovirus membrane penetration and apoptosis by the mu1 phi domainBid regulates the pathogenesis of neurotropic reovirus.Reovirus-induced apoptosis is preceded by increased cellular calpain activity and is blocked by calpain inhibitors.Reovirus growth in cell culture does not require the full complement of viral proteins: identification of a sigma1s-null mutant.Reovirus-induced apoptosis is mediated by TRAILReovirus-induced G(2)/M cell cycle arrest requires sigma1s and occurs in the absence of apoptosis.Reovirus binding to cell surface sialic acid potentiates virus-induced apoptosisReovirus infection activates JNK and the JNK-dependent transcription factor c-Jun.Reovirus-induced sigma1s-dependent G(2)/M phase cell cycle arrest is associated with inhibition of p34(cdc2).Reovirus-induced alterations in gene expression related to cell cycle regulation.Rotavirus genome segment 7 (NSP3) is a determinant of extraintestinal spread in the neonatal mouse.Reovirus-induced apoptosis requires mitochondrial release of Smac/DIABLO and involves reduction of cellular inhibitor of apoptosis protein levels.Reovirus infection and tissue injury in the mouse central nervous system are associated with apoptosis.Reovirus-induced apoptosis of MDCK cells is not linked to viral yield and is blocked by Bcl-2.Reverse Genetics for Fusogenic Bat-Borne Orthoreovirus Associated with Acute Respiratory Tract Infections in Humans: Role of Outer Capsid Protein σC in Viral Replication and Pathogenesis.Mechanisms of apoptosis during reovirus infection.Mechanisms of reovirus-induced cell death and tissue injury: role of apoptosis and virus-induced perturbation of host-cell signaling and transcription factor activation.Construction and characterization of a reovirus double temperature-sensitive mutant.From touchdown to transcription: the reovirus cell entry pathwayReovirus receptors, cell entry, and proapoptotic signaling.Down-regulation of cFLIP following reovirus infection sensitizes human ovarian cancer cells to TRAIL-induced apoptosis.Experimental reovirus-induced acute flaccid paralysis and spinal motor neuron cell deathInhibition of NF-kappa B activity and cFLIP expression contribute to viral-induced apoptosis.Reovirus activates a caspase-independent cell death pathway.JNK regulates the release of proapoptotic mitochondrial factors in reovirus-infected cells.Reovirus μ1 Protein Affects Infectivity by Altering Virus-Receptor Interactions.Nonstructural protein σ1s mediates reovirus-induced cell cycle arrest and apoptosis.Reovirus infection or ectopic expression of outer capsid protein micro1 induces apoptosis independently of the cellular proapoptotic proteins Bax and Bak.Thermostability of reovirus disassembly intermediates (ISVPs) correlates with genetic, biochemical, and thermodynamic properties of major surface protein mu1.Reovirus apoptosis and virulence are regulated by host cell membrane penetration efficiency.JAK-STAT signaling pathways are activated in the brain following reovirus infection.The reovirus μ1 340-343 loop controls entry related conformational changes.Reovirus outer capsid protein micro1 induces apoptosis and associates with lipid droplets, endoplasmic reticulum, and mitochondria.The delta region of outer-capsid protein micro 1 undergoes conformational change and release from reovirus particles during cell entry.Nonstructural protein sigma1s is a determinant of reovirus virulence and influences the kinetics and severity of apoptosis induction in the heart and central nervous system.Viral gene expression potentiates reovirus-induced necrosis.Genes Induced by Reovirus Infection Have a Distinct Modular Cis-Regulatory ArchitectureReovirus infection of the CNS enhances iNOS expression in areas of virus-induced injury.
P2860
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P2860
Linkage between reovirus-induced apoptosis and inhibition of cellular DNA synthesis: role of the S1 and M2 genes.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Linkage between reovirus-induc ...... : role of the S1 and M2 genes.
@ast
Linkage between reovirus-induc ...... : role of the S1 and M2 genes.
@en
type
label
Linkage between reovirus-induc ...... : role of the S1 and M2 genes.
@ast
Linkage between reovirus-induc ...... : role of the S1 and M2 genes.
@en
prefLabel
Linkage between reovirus-induc ...... : role of the S1 and M2 genes.
@ast
Linkage between reovirus-induc ...... : role of the S1 and M2 genes.
@en
P2093
P2860
P1433
P1476
Linkage between reovirus-induc ...... : role of the S1 and M2 genes.
@en
P2093
M K Squier
S M Oberhaus
T S Dermody
P2860
P304
P407
P577
1996-11-01T00:00:00Z