The delta region of outer-capsid protein micro 1 undergoes conformational change and release from reovirus particles during cell entry.
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Potential for Improving Potency and Specificity of Reovirus Oncolysis with Next-Generation Reovirus VariantsDiminished reovirus capsid stability alters disease pathogenesis and littermate transmissionReovirus polymerase λ3 localized by cryo-electron microscopy of virions at a resolution of 7.6 ÅThe reovirus sigma1 aspartic acid sandwich: a trimerization motif poised for conformational changeApoptosis induction influences reovirus replication and virulence in newborn miceDeterminants of strain-specific differences in efficiency of reovirus entryRequirements for the formation of membrane pores by the reovirus myristoylated micro1N peptide.Reovirus mu1 structural rearrangements that mediate membrane penetrationTransport to late endosomes is required for efficient reovirus infectionSimilar uptake but different trafficking and escape routes of reovirus virions and infectious subvirion particles imaged in polarized Madin-Darby canine kidney cells.Independent regulation of reovirus membrane penetration and apoptosis by the mu1 phi domainAdenovirus protein VI mediates membrane disruption following capsid disassembly.Features of reovirus outer capsid protein mu1 revealed by electron cryomicroscopy and image reconstruction of the virion at 7.0 Angstrom resolution.Virus-mediated compartmentalization of the host translational machinery.VP2 cleavage and the leucine ring at the base of the fivefold cylinder control pH-dependent externalization of both the VP1 N terminus and the genome of minute virus of mice.Reovirus variants selected for resistance to ammonium chloride have mutations in viral outer-capsid protein sigma3.Mammalian reovirus, a nonfusogenic nonenveloped virus, forms size-selective pores in a model membrane.Assembly of highly infectious rotavirus particles recoated with recombinant outer capsid proteins.Primed for Discovery: Atomic-Resolution Cryo-EM Structure of a Reovirus Entry IntermediateImpact of host proteases on reovirus infection in the respiratory tract.Mutations at the base of the icosahedral five-fold cylinders of minute virus of mice induce 3'-to-5' genome uncoating and critically impair entry functions.Thermostabilizing mutations in reovirus outer-capsid protein mu1 selected by heat inactivation of infectious subvirion particles.Thermolabilizing pseudoreversions in reovirus outer-capsid protein micro 1 rescue the entry defect conferred by a thermostabilizing mutation.From touchdown to transcription: the reovirus cell entry pathwayReovirus receptors, cell entry, and proapoptotic signaling.NPXY motifs in the beta1 integrin cytoplasmic tail are required for functional reovirus entry.A role for molecular chaperone Hsc70 in reovirus outer capsid disassemblyA positive-feedback mechanism promotes reovirus particle conversion to the intermediate associated with membrane penetration.Interferon-inducible transmembrane protein 3 (IFITM3) restricts reovirus cell entry.Secretory immunoglobulin A antibodies against the sigma1 outer capsid protein of reovirus type 1 Lang prevent infection of mouse Peyer's patches.Genetic determinants of reovirus pathogenesis in a murine model of respiratory infectionViroporins customize host cells for efficient viral propagation.Modulatory mechanisms of enterocyte apoptosis by viral, bacterial and parasitic pathogens.High-resolution 3D structures reveal the biological functions of reoviruses.Reovirus μ1 Protein Affects Infectivity by Altering Virus-Receptor Interactions.Conformational changes required for reovirus cell entry are sensitive to pH.Reduction of virion-associated σ1 fibers on oncolytic reovirus variants promotes adaptation toward tumorigenic cells.The μ1 72-96 loop controls conformational transitions during reovirus cell entry.Optimum length and flexibility of reovirus attachment protein σ1 are required for efficient viral infection.Cell entry-associated conformational changes in reovirus particles are controlled by host protease activity.
P2860
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P2860
The delta region of outer-capsid protein micro 1 undergoes conformational change and release from reovirus particles during cell entry.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
The delta region of outer-caps ...... s particles during cell entry.
@en
type
label
The delta region of outer-caps ...... s particles during cell entry.
@en
prefLabel
The delta region of outer-caps ...... s particles during cell entry.
@en
P2093
P2860
P1433
P1476
The delta region of outer-caps ...... us particles during cell entry
@en
P2093
Kartik Chandran
Marcelo Ehrlich
Max L Nibert
Tomas Kirchhausen
P2860
P304
13361-13375
P356
10.1128/JVI.77.24.13361-13375.2003
P407
P577
2003-12-01T00:00:00Z