The adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection.
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The adeno-associated virus type 2 regulatory proteins rep78 and rep68 interact with the transcriptional coactivator PC4.Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirusEfficient replication of adeno-associated virus type 2 vectors: a cis-acting element outside of the terminal repeats and a minimal sizeNovel cis-acting replication element in the adeno-associated virus type 2 genome is involved in amplification of integrated rep-cap sequences.Adeno-associated virus: from defective virus to effective vectorThe effect of DNA-dependent protein kinase on adeno-associated virus replicationAdeno-associated virus RNAs appear in a temporal order and their splicing is stimulated during coinfection with adenovirus.Rescue and autonomous replication of adeno-associated virus type 2 genomes containing Rep-binding site mutations in the viral p5 promoter.Conditional site-specific integration into human chromosome 19 by using a ligand-dependent chimeric adeno-associated virus/Rep protein.A chimeric protein containing the N terminus of the adeno-associated virus Rep protein recognizes its target site in an in vivo assay.Productive replication of adeno-associated virus can occur in human papillomavirus type 16 (HPV-16) episome-containing keratinocytes and is augmented by the HPV-16 E2 protein.Mechanism of Rep-mediated adeno-associated virus origin nicking.Factors affecting the terminal resolution site endonuclease, helicase, and ATPase activities of adeno-associated virus type 2 Rep proteinsRep-mediated nicking of the adeno-associated virus origin requires two biochemical activities, DNA helicase activity and transesterification.High mobility group chromosomal protein 1 binds to the adeno-associated virus replication protein (Rep) and promotes Rep-mediated site-specific cleavage of DNA, ATPase activity and transcriptional repression.The expression strategy of goose parvovirus exhibits features of both the Dependovirus and Parvovirus genera.Four-dimensional visualization of the simultaneous activity of alternative adeno-associated virus replication origins.The adeno-associated virus type 2 Rep protein regulates RNA processing via interaction with the transcription templateA pseudo-plaque method for infectious particle assay and clonal isolation of adeno-associated virus.Scalable generation of high-titer recombinant adeno-associated virus type 5 in insect cells.Characterization of the transcription profile of adeno-associated virus type 5 reveals a number of unique features compared to previously characterized adeno-associated virusesAdeno-associated virus: a key to the human genome?Inhibition of S-phase progression by adeno-associated virus Rep78 protein is mediated by hypophosphorylated pRbExpression profiles of bovine adeno-associated virus and avian adeno-associated virus display significant similarity to that of adeno-associated virus type 5Adeno-associated virus rep protein-mediated inhibition of transcription of the adenovirus major late promoter in vitro.Gene therapy using adeno-associated virus vectorsImproving clinical efficacy of adeno associated vectors by rational capsid bioengineering.A Comprehensive RNA Sequencing Analysis of the Adeno-Associated Virus (AAV) Type 2 Transcriptome Reveals Novel AAV Transcripts, Splice Variants, and Derived ProteinsThe cellular transcription factor SP1 and an unknown cellular protein are required to mediate Rep protein activation of the adeno-associated virus p19 promoter.The adeno-associated virus type 2 p40 promoter requires a proximal Sp1 interaction and a p19 CArG-like element to facilitate Rep transactivation.Encapsidation of adeno-associated virus type 2 Rep proteins in wild-type and recombinant progeny virions: Rep-mediated growth inhibition of primary human cellsComprehensive Small RNA-Seq of Adeno-Associated Virus (AAV)-Infected Human Cells Detects Patterns of Novel, Non-Coding AAV RNAs in the Absence of Cellular miRNA Regulation.Structural Studies of AAV2 Rep68 Reveal a Partially Structured Linker and Compact Domain ConformationIdentification of cellular proteins that interact with the adeno-associated virus rep proteinIdentification of a Functionally Relevant Adeno-Associated Virus Rep68 Oligomeric InterfaceNeonatal gene transfer leads to widespread correction of pathology in a murine model of lysosomal storage disease.Viral and Cellular Components of AAV2 Replication Compartments.Transcriptional analysis of the adeno-associated virus integration site.Promyelocytic leukemia protein is a cell-intrinsic factor inhibiting parvovirus DNA replication.Identification of an adeno-associated virus Rep protein binding site in the adenovirus E2a promoter.
P2860
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P2860
The adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
The adeno-associated virus (AA ...... during a productive infection.
@ast
The adeno-associated virus (AA ...... during a productive infection.
@en
type
label
The adeno-associated virus (AA ...... during a productive infection.
@ast
The adeno-associated virus (AA ...... during a productive infection.
@en
prefLabel
The adeno-associated virus (AA ...... during a productive infection.
@ast
The adeno-associated virus (AA ...... during a productive infection.
@en
P2093
P2860
P1433
P1476
The adeno-associated virus (AA ...... during a productive infection.
@en
P2093
D J Pereira
D M McCarty
N Muzyczka
P2860
P304
P407
P577
1997-02-01T00:00:00Z