Nanomolar CFTR inhibition by pore-occluding divalent polyethylene glycol-malonic acid hydrazides
about
Chloride channels as drug targets.Antidiarrheal efficacy and cellular mechanisms of a Thai herbal remedyCrofelemer, an antisecretory antidiarrheal proanthocyanidin oligomer extracted from Croton lechleri, targets two distinct intestinal chloride channelsCFTR inhibitors.Poly(ethylene glycol) as a scaffold for high-affinity open-channel blockers of the mouse nicotinic acetylcholine receptor.Benzopyrimido-pyrrolo-oxazine-dione (R)-BPO-27 Inhibits CFTR Chloride Channel Gating by Competition with ATPConvective washout reduces the antidiarrheal efficacy of enterocyte surface-targeted antisecretory drugsSecretory diarrhoea: mechanisms and emerging therapies.Thiazolidinone CFTR inhibitors with improved water solubility identified by structure-activity analysisABSOLUTE CONFIGURATION AND BIOLOGICAL PROPERTIES OF ENANTIOMERS OF CFTR INHIBITOR BPO-27Revisiting the role of cystic fibrosis transmembrane conductance regulator and counterion permeability in the pH regulation of endocytic organelles.Chloride channel-targeted therapy for secretory diarrheasRecent advances and new perspectives in targeting CFTR for therapy of cystic fibrosis and enterotoxin-induced secretory diarrheas.Transport and function of chloride in vascular smooth muscles.Cholera: pathophysiology and emerging therapeutic targets.Cystic fibrosis transmembrane regulator correctors and potentiators.CFTR pharmacology.Nanomolar potency pyrimido-pyrrolo-quinoxalinedione CFTR inhibitor reduces cyst size in a polycystic kidney disease model.Potent, metabolically stable benzopyrimido-pyrrolo-oxazine-dione (BPO) CFTR inhibitors for polycystic kidney disease.Aquaporin 9 phosphorylation mediates membrane localization and neutrophil polarization.Benzopyrimido-pyrrolo-oxazine-dione CFTR inhibitor (R)-BPO-27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins.
P2860
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P2860
Nanomolar CFTR inhibition by pore-occluding divalent polyethylene glycol-malonic acid hydrazides
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Nanomolar CFTR inhibition by p ...... glycol-malonic acid hydrazides
@ast
Nanomolar CFTR inhibition by p ...... glycol-malonic acid hydrazides
@en
type
label
Nanomolar CFTR inhibition by p ...... glycol-malonic acid hydrazides
@ast
Nanomolar CFTR inhibition by p ...... glycol-malonic acid hydrazides
@en
prefLabel
Nanomolar CFTR inhibition by p ...... glycol-malonic acid hydrazides
@ast
Nanomolar CFTR inhibition by p ...... glycol-malonic acid hydrazides
@en
P2093
P2860
P1476
Nanomolar CFTR inhibition by p ...... glycol-malonic acid hydrazides
@en
P2093
A S Verkman
N D Sonawane
Olga Zegarra-Moran
P2860
P304
P356
10.1016/J.CHEMBIOL.2008.05.015
P577
2008-07-01T00:00:00Z