Revisiting the role of cystic fibrosis transmembrane conductance regulator and counterion permeability in the pH regulation of endocytic organelles.
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Role of Sphingolipids in the Pathobiology of Lung InflammationMycobacterium tuberculosis responds to chloride and pH as synergistic cues to the immune status of its host cellSecond-hand cigarette smoke impairs bacterial phagocytosis in macrophages by modulating CFTR dependent lipid-raftsLysosomal Re-acidification Prevents Lysosphingolipid-Induced Lysosomal Impairment and Cellular ToxicitySodium/hydrogen exchanger NHA2 is critical for insulin secretion in β-cellsThe cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in maturation stage ameloblasts, odontoblasts and bone cellsDysfunctional CFTR alters the bactericidal activity of human macrophages against Pseudomonas aeruginosa.Functional vacuolar ATPase (V-ATPase) proton pumps traffic to the enterocyte brush border membrane and require CFTR.Chloride channels of intracellular membranesListeria monocytogenes exploits cystic fibrosis transmembrane conductance regulator (CFTR) to escape the phagosome.Degradation of Alzheimer's amyloid fibrils by microglia requires delivery of ClC-7 to lysosomes.Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis.Pseudomonas aeruginosa-induced bleb-niche formation in epithelial cells is independent of actinomyosin contraction and enhanced by loss of cystic fibrosis transmembrane-conductance regulator osmoregulatory function.Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia.The rs3737964 single-nucleotide polymorphism of the chloride channel-6 gene as a risk factor for coronary heart disease.Intracellular chloride channel protein CLIC1 regulates macrophage function through modulation of phagosomal acidification.Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis.Low levels of insulin-like growth factor-1 contribute to alveolar macrophage dysfunction in cystic fibrosis.Impaired endolysosomal function disrupts Notch signalling in optic nerve astrocytesTALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs.Disease-causing mutations in the cystic fibrosis transmembrane conductance regulator determine the functional responses of alveolar macrophages4-Aminopyridine promotes functional recovery and remyelination in acute peripheral nerve injuryInfluenza Virus Overcomes Cellular Blocks To Productively Replicate, Impacting Macrophage FunctionGenotype-specific alterations in vascular smooth muscle cell function in cystic fibrosis piglets.Mycobacteria and the intraphagosomal environment: take it with a pinch of salt(s)!Functional Rescue of F508del-CFTR Using Small Molecule CorrectorsRepairing mutated proteins--development of small molecules targeting defects in the cystic fibrosis transmembrane conductance regulator.Chloride transport.Determination of cell uptake pathways for tumor inhibitor lysyl oxidase propeptide.Cystic Fibrosis Lung Immunity: The Role of the MacrophageCFTR Folding Consortium: methods available for studies of CFTR folding and correctionStaphylococcus aureus Survives in Cystic Fibrosis Macrophages, Forming a Reservoir for Chronic Pneumonia.Endocytic sorting of CFTR variants monitored by single-cell fluorescence ratiometric image analysis (FRIA) in living cells.Intracellular survival of Burkholderia cepacia complex in phagocytic cells.Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell.A cation counterflux supports lysosomal acidification.Ceramide in cystic fibrosis: a potential new target for therapeutic intervention.Lysosomal pH and analysis of the counter ion pathways that support acidification.Optimal complement-mediated phagocytosis of Pseudomonas aeruginosa by monocytes is cystic fibrosis transmembrane conductance regulator-dependent.Acidification-dependent activation of CD1d-restricted natural killer T cells is intact in cystic fibrosis.
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Revisiting the role of cystic fibrosis transmembrane conductance regulator and counterion permeability in the pH regulation of endocytic organelles.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 06 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Revisiting the role of cystic ...... ation of endocytic organelles.
@en
Revisiting the role of cystic ...... ation of endocytic organelles.
@nl
type
label
Revisiting the role of cystic ...... ation of endocytic organelles.
@en
Revisiting the role of cystic ...... ation of endocytic organelles.
@nl
prefLabel
Revisiting the role of cystic ...... ation of endocytic organelles.
@en
Revisiting the role of cystic ...... ation of endocytic organelles.
@nl
P2093
P2860
P50
P356
P1476
Revisiting the role of cystic ...... ation of endocytic organelles.
@en
P2093
Dieter Gruenert
Florian Bossard
Gabriella Wojewodka
Herve Barriere
Miklos Bagdany
P2860
P304
P356
10.1091/MBC.E09-01-0061
P577
2009-05-06T00:00:00Z