Thermostabilizing mutations in reovirus outer-capsid protein mu1 selected by heat inactivation of infectious subvirion particles.
about
Peroxisomes are signaling platforms for antiviral innate immunity3.3 A cryo-EM structure of a nonenveloped virus reveals a priming mechanism for cell entry.Determinants of strain-specific differences in efficiency of reovirus entryRequirements for the formation of membrane pores by the reovirus myristoylated micro1N peptide.Recruitment of cellular clathrin to viral factories and disruption of clathrin-dependent trafficking.Independent regulation of reovirus membrane penetration and apoptosis by the mu1 phi domainA novel pathogenic Mammalian orthoreovirus from diarrheic pigs and Swine blood meal in the United StatesThermolabilizing pseudoreversions in reovirus outer-capsid protein micro 1 rescue the entry defect conferred by a thermostabilizing mutation.Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes.From touchdown to transcription: the reovirus cell entry pathwayA positive-feedback mechanism promotes reovirus particle conversion to the intermediate associated with membrane penetration.Interferon-inducible transmembrane protein 3 (IFITM3) restricts reovirus cell entry.Reovirus μ1 Protein Affects Infectivity by Altering Virus-Receptor Interactions.Conformational changes required for reovirus cell entry are sensitive to pH.The μ1 72-96 loop controls conformational transitions during reovirus cell entry.Optimum length and flexibility of reovirus attachment protein σ1 are required for efficient viral infection.Reovirus apoptosis and virulence are regulated by host cell membrane penetration efficiency.The reovirus μ1 340-343 loop controls entry related conformational changes.
P2860
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P2860
Thermostabilizing mutations in reovirus outer-capsid protein mu1 selected by heat inactivation of infectious subvirion particles.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Thermostabilizing mutations in ...... nfectious subvirion particles.
@ast
Thermostabilizing mutations in ...... nfectious subvirion particles.
@en
type
label
Thermostabilizing mutations in ...... nfectious subvirion particles.
@ast
Thermostabilizing mutations in ...... nfectious subvirion particles.
@en
prefLabel
Thermostabilizing mutations in ...... nfectious subvirion particles.
@ast
Thermostabilizing mutations in ...... nfectious subvirion particles.
@en
P2093
P2860
P1433
P1476
Thermostabilizing mutations in ...... nfectious subvirion particles.
@en
P2093
Jason K Middleton
Max L Nibert
Melina A Agosto
Tonya F Severson
P2860
P304
P356
10.1016/J.VIROL.2006.11.024
P407
P577
2007-01-17T00:00:00Z