Cleavage susceptibility of reovirus attachment protein sigma1 during proteolytic disassembly of virions is determined by a sequence polymorphism in the sigma1 neck.
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Potential for Improving Potency and Specificity of Reovirus Oncolysis with Next-Generation Reovirus VariantsDiminished reovirus capsid stability alters disease pathogenesis and littermate transmissionCrystal structure of reovirus attachment protein sigma1 reveals evolutionary relationship to adenovirus fiberCrystal Structure of Reovirus Attachment Protein σ1 in Complex with Sialylated OligosaccharidesApoptosis induction influences reovirus replication and virulence in newborn miceMutant cells selected during persistent reovirus infection do not express mature cathepsin L and do not support reovirus disassembly.Identification of carbohydrate-binding domains in the attachment proteins of type 1 and type 3 reovirusesA single mutation in the carboxy terminus of reovirus outer-capsid protein sigma 3 confers enhanced kinetics of sigma 3 proteolysis, resistance to inhibitors of viral disassembly, and alterations in sigma 3 structure.The viral sigma1 protein and glycoconjugates containing alpha2-3-linked sialic acid are involved in type 1 reovirus adherence to M cell apical surfaces.Reovirus receptors and pathogenesis.A novel pathogenic Mammalian orthoreovirus from diarrheic pigs and Swine blood meal in the United StatesThermostabilizing mutations in reovirus outer-capsid protein mu1 selected by heat inactivation of infectious subvirion particles.Mechanisms of reovirus bloodstream dissemination.From touchdown to transcription: the reovirus cell entry pathwayThe oncolytic effect in vivo of reovirus on tumour cells that have survived reovirus cell killing in vitro.Genetic determinants of reovirus pathogenesis in a murine model of respiratory infectionHigh similarity of novel orthoreovirus detected in a child hospitalized with acute gastroenteritis to mammalian orthoreoviruses found in bats in Europe.Junctional adhesion molecule a serves as a receptor for prototype and field-isolate strains of mammalian reovirus.Reduction of virion-associated σ1 fibers on oncolytic reovirus variants promotes adaptation toward tumorigenic cells.Optimum length and flexibility of reovirus attachment protein σ1 are required for efficient viral infection.Complete in vitro assembly of the reovirus outer capsid produces highly infectious particles suitable for genetic studies of the receptor-binding protein.Addition of exogenous protease facilitates reovirus infection in many restrictive cells.Protective immunoglobulin A and G antibodies bind to overlapping intersubunit epitopes in the head domain of type 1 reovirus adhesin sigma1.A molecular dynamics study of reovirus attachment protein sigma1 reveals conformational changes in sigma1 structure.The delta region of outer-capsid protein micro 1 undergoes conformational change and release from reovirus particles during cell entry.Putative autocleavage of outer capsid protein micro1, allowing release of myristoylated peptide micro1N during particle uncoating, is critical for cell entry by reovirus.A plasmid-based reverse genetics system for animal double-stranded RNA viruses.Junctional adhesion molecule-A is required for hematogenous dissemination of reovirus
P2860
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P2860
Cleavage susceptibility of reovirus attachment protein sigma1 during proteolytic disassembly of virions is determined by a sequence polymorphism in the sigma1 neck.
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Cleavage susceptibility of reo ...... lymorphism in the sigma1 neck.
@ast
Cleavage susceptibility of reo ...... lymorphism in the sigma1 neck.
@en
type
label
Cleavage susceptibility of reo ...... lymorphism in the sigma1 neck.
@ast
Cleavage susceptibility of reo ...... lymorphism in the sigma1 neck.
@en
prefLabel
Cleavage susceptibility of reo ...... lymorphism in the sigma1 neck.
@ast
Cleavage susceptibility of reo ...... lymorphism in the sigma1 neck.
@en
P2093
P2860
P1433
P1476
Cleavage susceptibility of reo ...... lymorphism in the sigma1 neck.
@en
P2093
E S Barton
J D Chappell
M L Nibert
T S Dermody
P2860
P304
P577
1998-10-01T00:00:00Z