Analysis of the p53-mediated G1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoprotein
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Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600The causal relation between human papillomavirus and cervical cancer.The structure and regulation of Cullin 2 based E3 ubiquitin ligases and their biological functionsThe papillomavirus E1 helicase activates a cellular DNA damage response in viral replication fociHuman keratinocytes are efficiently immortalized by a Rho kinase inhibitorThe human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2.The human papillomavirus type 58 E7 oncoprotein modulates cell cycle regulatory proteins and abrogates cell cycle checkpoints.Human papilloma virus E7 oncoprotein abrogates the p53-p21-DREAM pathway.Human T-cell leukemia virus type 1 Tax and cell cycle progression: role of cyclin D-cdk and p110Rb.Anchorage-independent transcription of the cyclin A gene induced by the E7 oncoprotein of human papillomavirus type 16.Repression of the integrated papillomavirus E6/E7 promoter is required for growth suppression of cervical cancer cells.Critical roles for non-pRb targets of human papillomavirus type 16 E7 in cervical carcinogenesisHuman papillomavirus E7 oncoprotein overrides the tumor suppressor activity of p21Cip1 in cervical carcinogenesis.The Epstein-Barr virus protein BRLF1 activates S phase entry through E2F1 induction.Expression signatures of HOX cluster genes in cervical cancer pathogenesis: Impact of human papillomavirus type 16 oncoprotein E7Destabilization of the retinoblastoma tumor suppressor by human papillomavirus type 16 E7 is not sufficient to overcome cell cycle arrest in human keratinocytes.Inactivation of p21 by E1A leads to the induction of apoptosis in DNA-damaged cells.Cyclin E induction by genotoxic stress leads to apoptosis of hematopoietic cells.Examination of the pRb-dependent and pRb-independent functions of E7 in vivo.E2F-Rb complexes assemble and inhibit cdc25A transcription in cervical carcinoma cells following repression of human papillomavirus oncogene expressionDisruption of the G1/S transition in human papillomavirus type 16 E7-expressing human cells is associated with altered regulation of cyclin EInteractions with pocket proteins contribute to the role of human papillomavirus type 16 E7 in the papillomavirus life cycle.The E7 proteins of low- and high-risk human papillomaviruses share the ability to target the pRB family member p130 for degradationInactivation of both the retinoblastoma tumor suppressor and p21 by the human papillomavirus type 16 E7 oncoprotein is necessary to inhibit cell cycle arrest in human epithelial cells.Immortalized keratinocyte lines derived from human embryonic stem cellsInhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein.HPV16-E7 expression causes fluorodeoxyuridine-mediated radiosensitization in SW620 human colon cancer cells.The aqueous extract of Ficus religiosa induces cell cycle arrest in human cervical cancer cell lines SiHa (HPV-16 Positive) and apoptosis in HeLa (HPV-18 positive).Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivoRepression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways.Both conserved region 1 (CR1) and CR2 of the human papillomavirus type 16 E7 oncogene are required for induction of epidermal hyperplasia and tumor formation in transgenic mice.Human papillomavirus type 16 E6 and E7 oncogenes abrogate radiation-induced DNA damage responses in vivo through p53-dependent and p53-independent pathways.Mechanisms of human papillomavirus-induced oncogenesis.The Role of Elongin BC-Containing Ubiquitin Ligases.Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressorHuman papillomaviruses activate caspases upon epithelial differentiation to induce viral genome amplification.RNA interference for the treatment of papillomavirus disease.Human cells compromised for p53 function exhibit defective global and transcription-coupled nucleotide excision repair, whereas cells compromised for pRb function are defective only in global repair.Cellular transformation by human papillomaviruses: lessons learned by comparing high- and low-risk virusesRegulation of the retinoblastoma proteins by the human herpesviruses.
P2860
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P2860
Analysis of the p53-mediated G1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoprotein
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Analysis of the p53-mediated G ...... mavirus type 16 E7 oncoprotein
@ast
Analysis of the p53-mediated G ...... mavirus type 16 E7 oncoprotein
@en
type
label
Analysis of the p53-mediated G ...... mavirus type 16 E7 oncoprotein
@ast
Analysis of the p53-mediated G ...... mavirus type 16 E7 oncoprotein
@en
prefLabel
Analysis of the p53-mediated G ...... mavirus type 16 E7 oncoprotein
@ast
Analysis of the p53-mediated G ...... mavirus type 16 E7 oncoprotein
@en
P2860
P1433
P1476
Analysis of the p53-mediated G ...... mavirus type 16 E7 oncoprotein
@en
P2093
P2860
P304
P407
P577
1997-04-01T00:00:00Z